6 results about "Sodium chloroacetate" patented technology

The present application relates to a kind of preparation method of trifluoromethyl pyrazole compound, belong to the technical field of organic synthesis.The specific method is: (1) trifluoroacetyl ethyl acetate is first with hydrazine hydrate cyclization reaction and generates compound of formula III;(2) under the catalysis of base, compound of formula III is reacted with difluoromethylation reagent and generates compound of formula II;(3) compound of formula II is reacted with methylating agent and obtains compound of formula I;The difluoromethylation reagent is difluoro-monochloromethane or sodium difluoro-monochloroacetate;The methylating agent is chloromethane, bromomethane, iodomethane, dimethyl sulfate or dimethyl carbonate.The present application is prepared by changing reaction route, and the higher-priced raw material methylhydrazine is replaced, and isomer impurity is no longer generated in the product prepared.Not only raw material cost is reduced, but also the purity of product is improved.

The application discloses a cationic modified rosin anion rosin size with charge reversal stability and a preparation method and application thereof, and belongs to the technical field of anion rosin size. The rosin size is composed of the following raw materials in parts by mass: rosin 100-200 parts; epichlorohydrin 30-90 parts; trimethylamine 3-7 parts; tetrabutylammonium bromide 0.5-1 part; anion starch emulsifier 5-8 parts, sodium dioctyl sulfosuccinate 5-8 parts; defoaming agent 0.5-2 parts; and water 100-240 parts; wherein the anion starch emulsifier is prepared by reacting cassava starch and sodium chloroacetate under alkaline conditions. The modified rosin liquid and the anion emulsifier are emulsified by using a high-temperature normal-pressure phase inversion method to prepare the cationic modified rosin anion rosin size based on the charge reversal stability, and the cationic modified rosin anion rosin size has the characteristics of no chloropropanol, no organic chlorine and good stability, and can realize acid to neutral sizing.

The application discloses a preparation method of 2,4-dichlorophenoxyacetic acid synthesized by composite molecular sieve ZSM-5 and a water-reducing process, and relates to the following steps: under alkaline conditions, 2,4-dichlorophenol is reacted with a sodium chloroacetate solution under the catalysis of a composite molecular sieve catalyst to obtain 2,4-dichlorophenoxyacetic acid sodium salt crude product through condensation; and then hydrolysis and hydrochloric acid acidification are carried out to obtain 2,4-dichlorophenoxyacetic acid product. The process can reduce energy consumption, shorten reaction time and reduce production cost in obtaining 2,4-dichlorophenoxyacetic acid, and can improve the conversion rate and yield of the product and the color of the product. When a new batch of 2,4-dichlorophenoxyacetic acid sodium salt crude product is dissolved in the acidification reaction, the washing water of the last batch of 2,4-dichlorophenoxyacetic acid is used as the solvent reaction liquid, and the washing water of the last batch is used for the first water washing of the final product and is used in turn. The water consumption is reduced, the wastewater treatment cost is reduced, the conversion rate and yield of the product are improved, the product has high purity, the process is simple, the conditions are mild, and the raw materials can be recycled.

The application provides a method for preparing sodium N,N-dimethylglycinate. The method comprises the following steps: (1) adding a sodium chloroacetate solution into a dimethylamine solution and reacting to obtain a reaction solution; wherein the pH of the reaction is controlled to be greater than 10.5 by adding alkali before or during the reaction; (2) mixing the reaction solution with hydrochloric acid after deamination treatment to obtain a solution containing N,N-dimethylglycinate; (3) reacting the solution containing N,N-dimethylglycinate with sodium hydroxide after impurity removal, solvent crystallization and drying to obtain a sodium N,N-dimethylglycinate product. The method can obtain sodium N,N-dimethylglycinate with high purity, high yield and good stability, and by controlling the drying temperature of the wet product of sodium N,N-dimethylglycinate, the sodium N,N-dimethylglycinate hydrate with good stability can be obtained.

The present application relates to functional COFs cellulose membrane, and in particular to a kind of bifunctional COFs cellulose membrane and its preparation method and application.The preparation method of the bifunctional COFs material includes:1) in water / isopropyl alcohol mixed solvent, under the action of sodium hydroxide and sodium chloroacetate, cotton fiber is carboxymethylated, and carboxymethylated cotton fiber is obtained;2) in acetonitrile solution, under the action of TFTA, TAPM, aniline and acetic acid, the carboxymethylated cotton fiber is prepared to obtain solid I, i.e.FCOF@CMCF;3) in toluene, the solid I is reacted with 1,3-propane sulfonic acid lactone, and the bifunctional COFs material is prepared.The removal rate of the bifunctional COFs material of the present application to fluoroquinolone antibiotic is up to 90% or more.