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Hiccup treating medicine and its prepn process

A drug and weight ratio technology, applied in the field of medicine, can solve the problems of reducing curative effect, inconvenience for doctors and patients, and volatile loss

Inactive Publication Date: 2007-11-07
JINAN KANGZHONG PHARMA TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

"Dingxiang Shidi Decoction" comes from "Syndrome Causes and Pulse Treatment". It is a traditional Chinese medicine compound. At present, there is no Chinese patent medicine. Only decoction can be used to treat hiccup patients. The decoction has the following shortcomings. First, the prescription of "Dingxiang Shidi Decoction" contains Clove and ginger, one of the active ingredients of the two medicinal materials contains volatile oil, which is easily volatile and lost during the preparation of the decoction, reducing the curative effect
Second, the preparation of decoction requires patients to decoct it themselves, which brings a lot of inconvenience to doctors and patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Take the following Chinese medicine raw materials

[0022] Clove 208g, persimmon stalk 525g, ginseng 258g, ginger 525g.

[0023] (1) Take cloves and ginger and add 4 times the amount of water to extract the volatile oil. The obtained volatile oil is clathrated with β-cyclodextrin with 6 times the amount of volatile oil, dried below 40°C, and sieved to obtain the volatile oil inclusion compound . Filter the liquid medicine, concentrate to a thick paste to obtain a thick paste 1;

[0024] (2) Take ginseng and persimmon stalks and add 10 times and 8 times the amount of water to decoct twice, the first time is 2 hours, the second time is 1 hour, the two liquid medicines are combined, filtered, concentrated to a thick paste, and thickened ointment 2;

[0025] (3) Combine thick cream 1 and thick cream 2, dry and pulverize to make dry cream powder;

[0026] (4) Add 6 g of micropowder silica gel and 20 g of sodium starch glycolate to the dry cream powder to make granules, a...

Embodiment 2

[0028] Take the following Chinese medicine raw materials

[0029] Clove 208g, persimmon stalk 525g, ginseng 258g, ginger 525g.

[0030] (1) Take cloves and ginger and add 5 times the amount of water to extract the volatile oil, and store the volatile oil separately; filter the medicinal solution, concentrate to a thick paste to obtain thick paste 1;

[0031] (2) Take ginseng and persimmon stalks, add 12 times and 10 times of water respectively, decoct twice, each time for 1.5 hours, combine the two liquid medicines, filter, concentrate to a thick paste, and obtain thick paste 2;

[0032] (3) Combine thick paste 1 and thick paste 2, dry and pulverize to make dry paste powder.

[0033] (4) Add 20g of starch and 16g of micropowdered silica gel to dry cream powder to make granules, add volatile oil and mix well to make 1000 capsules.

Embodiment 3

[0035] Take the following Chinese medicine raw materials

[0036] Clove 208g, persimmon stalk 525g, ginseng 258g, ginger 525g.

[0037] (1) Take cloves and ginger and add 6 times the amount of water to extract the volatile oil, and store the volatile oil separately; filter the medicinal solution, concentrate to a thick paste to obtain thick paste 1;

[0038] (2) Take ginseng and persimmon stalks and add 12 and 10 times the amount of water to decoct twice, each time for 2 hours and 1.5 hours respectively, combine the two liquid medicines, filter, and concentrate to a thick paste to obtain thick paste 2;

[0039] (3) Combine thick cream 1 and thick cream 2, dry and pulverize to make dry cream powder;

[0040] (4) Add sucrose powder and dextrin to the dry cream powder to make granules, dry, granulate, take the volatile oil obtained in (1), dissolve it with an appropriate amount of ethanol and spray it into granules to obtain 1000 g of granules.

[0041] List the applicant's cli...

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Abstract

The present invention discloses one kind of hiccup treating medicine and its preparation process, and belongs to the field of medicine technology. The medicine is prepared with clove, calyx and receptacle of persimmon, ginseng and ginger, and through extracting volatile oil with clove and ginger, decocting and concentrating the decoction, drying the extractum, adding supplementary material and other steps to form tablet, capsule, granule, etc. The hiccup treating medicine of the present invention has high curative effect and convenient taking.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a medicine for treating hiccups and a preparation method thereof. Background technique [0002] Hiccup is a clonic involuntary contracture of auxiliary respiratory muscles such as the diaphragm and intercostal muscles, accompanied by sudden locking of the door during inspiration, air rapidly flowing into the trachea, and specific sounds. Hiccups that are frequent or last for more than 24 hours are called intractable hiccups, which mostly occur in certain diseases. [0003] Healthy people may have transient hiccups, which are mostly related to diet, especially eating too fast, overeating, consuming overheated or cold food and beverages, drinking alcohol, drinking carbonated beverages, etc. It can also be caused by changes in external temperature and excessive smoking. [0004] Traditional Chinese medicine believes that hiccups refer to stomach qi moving upwards and moving the ...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/16A61K9/20A61K9/48A61P43/00
Inventor 张为胜李诗标许竹梅张晶许翠萍
Owner JINAN KANGZHONG PHARMA TECH DEV
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