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Chinese medicine composition for treating kidney disease syndrome and preparing method

A technology of nephrotic syndrome and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., and can solve problems such as elevated

Active Publication Date: 2007-11-14
CONSUN PHARML NEI MENG GU
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, Professor Chen Yiping believes that the edema of hypoalbuminemia is caused by spleen deficiency and dampness. He reported that the method of replenishing qi and invigorating the spleen is used to treat hypoalbuminemia edema. , astragalus, yam, and atractylodes, clinically treated 107 patients with nephrotic syndrome hypoalbuminemia, and achieved a total effective rate of 92.5%. The serum albumin increased from 21.3 ± 12.6 before treatment to 36.8 ± 1 after treatment. 12.4, there is a significant difference before and after treatment, and there is also a significant difference compared with the prednisone control group

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The preparation of embodiment 1 capsule of the present invention

[0028] Take 50g of Radix Astragali, crush it into fine powder, and sieve it for later use; add 6 times the amount of 70% ethanol to 350g of black beans, 150g of atractylodes, and 100g of angelica, soak for 60 minutes, reflux for 2 hours, filter, and recover the ethanol from the filtrate for later use; add 200g of Chinese yam and 150g Astragalus, add 10 times the amount of water, extract once, 3 hours each time, filter, and concentrate the filtrate to a weight-volume ratio of medicinal materials to medicinal liquid of 1:2. 1-Type II clarifier B with a weight-to-volume ratio of 1:1, add 1% concentration of ZTC1+1-II clarifier B, stir once every 10 minutes, and after 1 hour, mix the total medicinal materials with ZTC1+1-II Type clarifier A with a weight-to-volume ratio of 1:1, add 1% concentration of ZTC1+1-II type clarifier A, stir once every 10 minutes, keep warm for 1 hour, remove impurities by high-spee...

Embodiment 2

[0029] The preparation of embodiment 2 capsules of the present invention

[0030] Take 100g of astragalus and grind it into fine powder, sieve it for later use; add 8 times the amount of 50% ethanol to 600g of black beans, 300g of atractylodes atractylodes, and 180g of angelica, soak for 30 minutes, reflux for 1 hour, filter, recover the ethanol from the filtrate, and set aside; add 300g of Chinese yam to the filter residue and 200g Astragalus membranaceus, add 8 times the amount of water respectively, extract 2 times, each time for 1 hour, filter, and the filtrate is concentrated to a weight-volume ratio of medicinal materials and medicinal liquid of 1:5. +1-Type II clarifier B with a weight-to-volume ratio of 1.4:1, add 1% concentration of ZTC1+1-Type II clarifier B, stir once every 30 minutes, and after 2 hours, mix according to the total medicinal materials and ZTC1+1- Type II clarifier A with a weight-to-volume ratio of 2.8:1, add 1% concentration of ZTC1+1-Type II clarifie...

Embodiment 3

[0031] The preparation of embodiment 3 capsules of the present invention

[0032] Take 50g of Radix Astragali, crush it into fine powder, and sieve it for later use; add 8 times the amount of 55% ethanol to 400g of black beans, 200g of herb atractylodes, and 70g of angelica, soak for 50 minutes, reflux for 3 hours, filter, recover the ethanol from the filtrate, and set aside; add 150g of Chinese yam to the filter residue and 100g Astragalus membranaceus, add 8 times the amount of water respectively, extract 3 times, each time for 1 hour, filter, and the filtrate is concentrated to a weight-volume ratio of medicinal materials and medicinal liquid of 1:3. +1-Type II clarifying agent B weight volume ratio 2: 1, add ZTC1+1-II type clarifying agent B of 1% concentration, stir 2 times every 20 minutes, after 2 hours, according to total medicinal materials and ZTC1+1- Type II clarifying agent A weight volume ratio is 4:1, add 1% concentration of ZTC1+1-Type II clarifying agent A, sti...

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Abstract

The present invention relates to a Chinese medicine composition for curing nephritic syndrome. Said Chinese medicine composition includes 5 Chinese medicinal materials of black soybean, astragalus root, atractylodes root, Chinese yam and Chinese angelica root. Said Chinese medicine composition can be made into tablet, capsule and granules preparation.

Description

field of invention [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating nephrotic syndrome and a preparation method thereof. Background technique [0002] Nephrotic syndrome is a common clinical syndrome, which is caused by glomerular lesions caused by various etiologies. Abnormal distribution of water (tissue edema, serous cavity effusion), hyperlipidemia. Severe hypoproteinemia can lead to body edema, peritoneal effusion, pleural effusion, pericardial effusion, gastrointestinal mucosal edema, cerebral edema, effective circulating blood volume decline, and severe cases endanger the life of the patient. At present, Western medicine mainly uses immunosuppressants and cytotoxic drugs to intervene in renal lesions to reduce the excretion of protein in the urine. At the same time, intravenous infusion of plasma and albumin is used to correct hypoalbuminemia. The toxic and side effec...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61K9/16A61K9/20A61K9/48A61P13/12
Inventor 黎倩熊祥安陈胜名黄云斌钟瑾黄晓玲石兴华
Owner CONSUN PHARML NEI MENG GU
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