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Particles for invigorating the spleen, oral liquid and condensed pills and method for preparing the same and the quality control method

A technology for concentrating pills and oral liquids, which can be used in medical preparations containing active ingredients, pill delivery, liquid delivery, etc., and can solve the problems of large dosage, rough quality, and inconvenient taking.

Active Publication Date: 2008-01-02
ZHEJIANG ASEN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Guipi Decoction comes from "Jisheng Fang". , polygala (made), jujube seed (stir-fried), longan meat, angelica, woody, jujube (pitted) and other traditional Chinese medicines, which are recorded in the "Pharmacopoeia of the People's Republic of China" (1995 edition), and are big honey pills , small honeyed pills or water honeyed pills, which have the functions of nourishing qi, invigorating the spleen, nourishing blood and calming the nerves, and are used for symptoms such as deficiency of the heart and spleen, shortness of breath, palpitations, insomnia and dreaminess, dizziness, fatigue, loss of appetite, metrorrhagia, hematochezia, etc. , because the original preparations, such as large honeyed pills, small honeyed pills, water honeyed pills and watered pills, are directly crushed from Chinese herbal medicines, the quality is rough, the content of impurities is large, the dosage is large, it is inconvenient to take, the absorption is slow, the quality is difficult to control, and the curative effect is limited.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] Codonopsis 140g Atractylodes macrocephala (fried) 280g Astragalus (honey-roasted) 140g Licorice (honey-roasted) 70g

[0091] Poria cocos 280g Polygala (made) 280g Suanzaoren (fried) 140g Longan meat 280g

[0092] Angelica 280g Woody Fragrance 70g Jujube (pitted) 70g

[0093] [Technology] The above eleven flavors are crushed or chopped into suitable granules, and extracted twice with water under slight boiling and dynamic reflux. For the first time, add 10 times the amount of water to extract for 1 hour, and for the second time, add 5 times the amount of water to extract for 0.5 hours, and combine The medicinal solution is filtered, the filtrate is concentrated under reduced pressure to the extract with a relative density of 1.05-1.15 (50°C), filtered, an appropriate amount of dextrin is added to the filtrate, mixed evenly, and made into 1000g of granules to obtain the product.

Embodiment 2

[0095] Codonopsis 70g Atractylodes macrocephala 140g Astragalus 70g Licorice 35g

[0096] Poria 140g Polygala 140g Suanzaoren 70g Longan meat 140g

[0097] Angelica 140g Woody Fragrance 35g Jujube 35g

[0098] Its preparation method is as follows:

[0099] The above eleven flavors are crushed or chopped into suitable granules, extracted twice under dynamic reflux with water, adding 10 times the amount of water for 1 hour, and adding 5 times the amount of water for 0.5 hours for the second time, combining the liquid medicine, Filtrate, concentrate the filtrate under reduced pressure to an extract with a relative density of 1.05-1.15 (50°C), filter, add an appropriate amount of dextrin to the filtrate, mix well, and make 1000g of granules to obtain.

Embodiment 3

[0101] Codonopsis 280g Atractylodes macrocephala 560g Astragalus 280g Licorice 140g

[0102] Poria cocos 560g Polygala 560g Suanzaoren 280g Longan meat 560g

[0103] Angelica 560g Woody Fragrance 140g Jujube 140g

[0104] Its preparation method is as follows:

[0105] The above eleven flavors are crushed or chopped into suitable granules, extracted twice under dynamic reflux with water, adding 10 times the amount of water for 1 hour, and adding 5 times the amount of water for 0.5 hours for the second time, combining the liquid medicine, Filtrate, concentrate the filtrate under reduced pressure to an extract with a relative density of 1.05-1.15 (50°C), filter, add an appropriate amount of dextrin to the filtrate, mix well, and make 1000g of granules to obtain.

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PUM

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Abstract

The invention relates to a medicinal granule, oral liquid and concentrated pill, their preparation and quality control method, wherein the medicament is prepared from Chinese herbal materials including pilose asiabell root, white atractylodes rhizome, astragalus root, licorice root, poria cocos, polygala root, wild jujuba seeds, euphoria longan steud, Chinese angelica root, banksia rose and jujube.

Description

Technical field: [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a medicine with the functions of nourishing qi, invigorating the spleen, nourishing blood and calming the nerves. It is a traditional Chinese medicine preparation for heart and spleen deficiency, shortness of breath and palpitations, insomnia and dreaminess, dizziness, dizziness, fatigue and weakness, and loss of appetite. The preparation is made from traditional Chinese medicine raw materials such as Codonopsis pilosula, Atractylodes macrocephala, Radix Astragali, licorice, Poria cocos, polygala, jujube seed, longan meat, angelica, woody fragrance, and jujube. Background technique: [0002] Guipi Decoction comes from "Jisheng Fang". Guipi Pills are composed of Codonopsis, Atractylodes macrocephala (stir-fried), Astragalus (honey-roasted), licorice (honey-roasted), Poria cocos, Polygala (made), Suanzaoren (stir-fried), longan meat, Angelica, woody, jujub...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/77A61K9/20A61K9/16A61K9/10A61K9/08A61P1/14A61P25/20
Inventor 邓金明吴海英
Owner ZHEJIANG ASEN PHARMA
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