Surgical suture material with an antimicrobial surface and process for providing an antimicrobial coating on surgical suture material

A technique for surgical sutures and suture materials, applied to devices, coatings, surgical instruments, etc. that coat liquid on the surface, and can solve problems such as non-adhesion

Inactive Publication Date: 2008-04-30
HERAEUS MEDICAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, octenidine dichloride and dequalinium chloride did not show any significant adhesion to the surfaces of commonly used suture materials

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] 300 mg dequalinium chloride (Solmag) and 300 mg palmitic acid (Fluka) were dissolved in 28.800 g methanol (Fluka) at room temperature. A clear solution formed. A 50 cm length of braided polyglycolide filament (USP 2.0) was dipped into the solution. Methanol was then evaporated at room temperature. Coating quality was determined gravimetrically. The coating mass was 0.6 mg.

Embodiment 2

[0015] Octenidine dichloride (Dishman Pharmaceuticals) 600 mg and palmitic acid (Fluka) 600 mg were dissolved in 28.800 g methanol (Fluka) at room temperature. A clear solution formed. A 50 cm length of braided polyglycolide filament (USP 2.0) was dipped into the solution. Methanol was then evaporated at room temperature. Coating quality was determined gravimetrically. The coating mass was 1.4 mg.

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PUM

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Abstract

The present invention describes a surgical suture material having an antimicrobial surface exhibiting a coating comprising: at least one fatty acid, octenidine dichloride and / or diquinidine ammonium, and optionally oligolactate. Furthermore, the invention describes a method for coating surgical suture materials, characterized in that the filamentary material is wetted with a homogeneous methanolic solution containing octenidine dichloride and / or dequalinium chloride, And then methanol is evaporated to form a coating on the surface of the silk.

Description

technical field [0001] The subject matter of the present invention consists of two parts, a surgical suture material with an antimicrobial coating and a method for providing an antimicrobial coating on a surgical suture material. Background technique [0002] Based on the structure of surgical suture materials, they can be divided into monofilament and multifilament. Multifilaments can exhibit the so-called wicking effect. This refers to the migration of interstitial fluid along the filaments by capillary action. Microorganisms may also migrate with them, allowing the infection to spread along the filamentous material. Therefore, it is desirable to provide a finishing layer on surgical suture materials so that microorganisms are immobilized on the surface of the silk, thereby effectively preventing the migration of microorganisms along the silk. [0003] Braided polyglycolide multifilaments are of particular practical importance for absorbable suture materials. So far, o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L17/10
CPCA61B2017/00893A61L2300/606A61B17/06166A61L2300/208B05D2256/00A61L2300/802B05D1/18A61L2300/404A61L17/145A61L17/005A61B2017/00889
Inventor S·福格特K·D·屈恩H·比希纳
Owner HERAEUS MEDICAL
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