Surgical suture material with an antimicrobial surface and process for providing an antimicrobial coating on surgical suture material

A technique for surgical sutures and suture materials, applied to devices, coatings, surgical instruments, etc. that coat liquid on the surface, and can solve problems such as non-adhesion

A technique for surgical sutures and suture materials, applied to devices, coatings, surgical instruments, etc. that coat liquid on the surface, and can solve problems such as non-adhesion

CN101168071AInactive Publication Date: 2008-04-30HERAEUS MEDICAL
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] 300 mg dequalinium chloride (Solmag) and 300 mg palmitic acid (Fluka) were dissolved in 28.800 g methanol (Fluka) at room temperature. A clear solution formed. A 50 cm length of braided polyglycolide filament (USP 2.0) was dipped into the solution. Methanol was then evaporated at room temperature. Coating quality was determined gravimetrically. The coating mass was 0.6 mg.

Embodiment 2

[0015] Octenidine dichloride (Dishman Pharmaceuticals) 600 mg and palmitic acid (Fluka) 600 mg were dissolved in 28.800 g methanol (Fluka) at room temperature. A clear solution formed. A 50 cm length of braided polyglycolide filament (USP 2.0) was dipped into the solution. Methanol was then evaporated at room temperature. Coating quality was determined gravimetrically. The coating mass was 1.4 mg.

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Abstract

The surgical suture material comprises an antimicrobial surface comprising fatty acid (a), octenidine dichloride and / or dequalinium chloride (b), and optionally oligomeric lactic acid ester (c). The fatty acid is chosen from lauric acid, palmitic acid and stearic acid. The low alcohol used for coating surgical suture material, is chosen from ethanol, propanol and isopropanol. An independent claim is included for coating of surgical suture material.

Description

technical field [0001] The subject matter of the present invention consists of two parts, a surgical suture material with an antimicrobial coating and a method for providing an antimicrobial coating on a surgical suture material. Background technique [0002] Based on the structure of surgical suture materials, they can be divided into monofilament and multifilament. Multifilaments can exhibit the so-called wicking effect. This refers to the migration of interstitial fluid along the filaments by capillary action. Microorganisms may also migrate with them, allowing the infection to spread along the filamentous material. Therefore, it is desirable to provide a finishing layer on surgical suture materials so that microorganisms are immobilized on the surface of the silk, thereby effectively preventing the migration of microorganisms along the silk. [0003] Braided polyglycolide multifilaments are of particular practical importance for absorbable suture materials. So far, o...

Claims

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Application Information

Patent Timeline
30 Apr 2008
Publication
CN101168071A
IPC
A61L17/10
CPC
A61B2017/00893; A61L2300/606; A61B17/06166; A61L2300/208; B05D2256/00; A61L2300/802; B05D1/18; A61L2300/404
Inventors
S·福格特; K·D·屈恩