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Method for preparing novel triterpene saponin prunelloside A and prunelloside B

A technology of Prunella vulgaris and triterpenoids, which is applied in the field of triterpenoids and can solve the problems of no Prunella vulgaris new glycoside compounds and the like

Inactive Publication Date: 2008-05-28
石任兵 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report of new glycosides from Prunella vulgaris with 29 carbon atom triterpenoids as the core

Method used

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  • Method for preparing novel triterpene saponin prunelloside A and prunelloside B
  • Method for preparing novel triterpene saponin prunelloside A and prunelloside B
  • Method for preparing novel triterpene saponin prunelloside A and prunelloside B

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0074] Embodiment 1: new prunella glycoside A, B separation and purification process 1 (see Figure 13 )

Embodiment 2

[0075] Embodiment 2: new prunella glycoside A, B separation and purification process 2 (see Figure 14 )

Embodiment 3

[0076] Embodiment 3: new prunella glycoside A, B separation and purification process 3 (see Figure 15 )

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PUM

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Abstract

The invention discloses a new triterpenoid saponin compound as prunella spike glycoside A, and prunella spike glycoside B, which parent nucleus is 29 carbon atoms, and a relative separation and preparation method. The chemical formulas of the A and B are represented as right.

Description

technical field [0001] The present invention relates to a class of triterpenoid compound prunella glucoside with a new parent nucleus and a separation and identification method thereof. Background technique [0002] Prunella vulgaris is the dried fruit ear of Prunella vulgaris L., a plant of the Lamiaceae Prunella genus. It is bitter, pungent, cold in nature, and has the effects of clearing heat and improving eyesight, purging liver-fire, clearing heat and dispelling stagnation, etc. [1] . It can be used to treat headache and dizziness, crooked mouth and eyes, muscle and bone pain, red eyes and swelling, photophobia, tearing, mastitis, breast cancer, high blood pressure, lymphatic tuberculosis, infiltrating tuberculosis, simple goiter, mumps, blood metrorrhagia, leukorrhea, Pig, cattle, sheep infectious conjunctivitis, keratitis, etc. Modern pharmacological studies have confirmed that Prunella vulgaris has the functions of lowering blood pressure, lowering blood sugar, lo...

Claims

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Application Information

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IPC IPC(8): C07J63/00A61K36/536
Inventor 张兰珍石任兵郭亚健刘斌
Owner 石任兵
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