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Medicament compound for treating acute gout arthritis and preparing method thereof

A technology of acute gout and composition, which is applied in the field of traditional Chinese medicine preparation, can solve the problems of large side effects, etc., and achieve the effect of small side effects, simple production and quick effect

Inactive Publication Date: 2008-06-18
BEIJING ZHONGKE YONGHE PHARMA TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, Western medicine such as indomethacin, colchicine, allopurinol and glucocorticoids have a certain effect on this disease, but the side effects are large

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 2

[0050] Cangzhu 100g Phellodendron 130g Coix seed 300g Achyranthes bidentata 100g Gardenia 100g

[0051] Alisma 150g, Scutellaria 150g, Radix Paeoniae Rubra 130g, Fang 100g, Smilax tuckahoe 300g

[0052] Dilong 150g

[0053] Grind Earthworm into fine powder for later use; Atractylodes atractylodes, Phellodendron Phellodendri, Alisma, Azalea, and Fangji are crushed into coarse powder, heated and refluxed with 6 times the amount of 60-80% ethanol for 3 times, each time for 1.5 hours, combined extracts, filtered, Recover ethanol, concentrate to a relative density of 1.30-1.35 extract (heated at 50-60°C), and set aside; use 8-10 times the amount of water for the other five traditional Chinese medicines such as Coix seed, Gardenia, Achyranthes bidentata, Radix Paeoniae Rubra, and Smilax tuckahoe Decoct three times, followed by 2 hours, 1.5 hours, and 1 hour, filter, and concentrate the filtrate to a relative density of 1.15-1.20 extract (50-60°C heat test); combine the two extracts...

specific Embodiment 3

[0054] Cangzhu 300g Phellodendron 380g Coix seed 900g Achyranthes bidentata 300g Gardenia 300g

[0055] Alisma 450g, Scutellaria 450g, Radix Paeoniae Rubra 380g, Fangji 300g, Smilax 900g

[0056] Dilong 450g

[0057] Grind Earthworm into fine powder for later use; Atractylodes atractylodes, Phellodendron Phellodendri, Alisma, Azalea, and Fangji are crushed into coarse powder, heated and refluxed with 6 times the amount of 60-80% ethanol for 3 times, each time for 1.5 hours, combined extracts, filtered, Recover ethanol, concentrate to a relative density of 1.30-1.35 extract (heated at 50-60°C), and set aside; use 8-10 times the amount of water for the other five traditional Chinese medicines such as Coix seed, Gardenia, Achyranthes bidentata, Radix Paeoniae Rubra, and Smilax tuckahoe Decoct three times, followed by 2 hours, 1.5 hours, and 1 hour, filter, and concentrate the filtrate to a relative density of 1.15-1.20 extract (50-60°C heat test); combine the two extracts, add e...

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PUM

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Abstract

The invention discloses a drug combination for treating acute gouty arthritis. The combination is prepared by Rhizoma Atractylodis, Cortex Phellodendri, Semen Coicis, Radix Achyranthis Bidentatae, Fructus Gardeniae, Rhizoma Alismatis, Rhizoma Dioscoreae Hypoglaucae, Radix Paeoniae Rubra, Radix Stephaniae Tetrandrae, Smilax Glbra Roxb and Senecio pendulus. The medicine combination of the invention has the functions of removing heat and dampness, freeing channels and relieving pain and is used for treating the acute gouty arthritis which causes rubefaction, turgescence, heat, pain and limited activity of the ankles, the knees, the elbows, the wrists, the hands and the other joints of the feet, and the accompanying fever, chill, fatigue, anorexia and headache. The invention has the advantages of no atoxic effects and side effects, convenient materials collection, low cost, good cure effect, quick efficiency and simple preparation and has wide application values.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparation, and specifically relates to a traditional Chinese medicinal preparation for treating acute gouty arthritis and a preparation method thereof. Background technique [0002] Gouty arthritis is a disease caused by long-term purine metabolic disorders and increased blood uric acid, resulting in the deposition of uric acid crystals in joints and subcutaneous tissue. The main manifestations are recurrent joint redness, swelling, heat, pain and the formation of tophi, which can lead to joint deformity and dysfunction in severe cases. With the improvement of living standards and the change of dietary structure, the incidence of the disease is increasing every year, especially in middle-aged and elderly men. It is the most common arthritis among men over 40 years old, and it tends to become younger. The onset of the disease is rapid, the pain is severe, and recurrent, diff...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61K9/16A61K9/20A61K9/48A61P19/06A61P19/02A61K35/64A61K35/62
Inventor 程华鄢良张韬
Owner BEIJING ZHONGKE YONGHE PHARMA TECH
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