Sterile, drop-forming, multi-phase, emulsifier-free ophthalmic product

An emulsifier and preparation technology, which is applied in the direction of non-active ingredient medical preparations, aerosol delivery, emulsion delivery, etc., can solve the problems of patient discomfort and high viscosity, and achieve comfortable compatibility, low viscosity and good phase capacitive effect
CN101227891AInactive Publication Date: 2008-07-23BAUSCH & LOMB INC
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
BAUSCH & LOMB INC
Publication Date
2008-07-23
Estimated Expiration
Not applicable · inactive patent
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Abstract

The invention relates to a sterile, drop-forming, multi-phase, emulsifier-free ophthalmic product, in particular a gel product, comprising at least one liquid aqueous phase and at least one liquid hydrophobic phase, the product comprising at least one phosphate salt and having a viscosity in the range from > 200 mPa<.>s to < 2000 MPA<.>s.
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Description

technical field

[0001] The present invention relates to a sterile, instillable, multiphase, emulsifier-free ophthalmic preparation, especially a gel preparation. Said ophthalmic preparations can be used, for example, as artificial tears and for the treatment of "dry eyes". Background technique

[0002] It is known in the art that irritated or inflamed eyes, especially "dry eyes", Keratokonjunktivitis sicca, are treated with aqueous preparations for the ailment. The formulations are usually in the form of a liquid, gel, cream or ointment.

[0003] Disadvantageously, the solutions incorporate various contents that may cause allergies, produce irritation, or cause eye sensitization or incompatibility with the contents. It is also known that aqueous solutions often produce itching, burning or other unpleasant side effects when in contact with the eyes.

[0004] In addition, formulations in particular in the form of gels, creams or ointments have the disadvantage of causing ad...

Claims

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