A dehumidification device of a power cabinet comprises a bottom plate, an isolating frame, the power cabinet, an exhaust device, a drying device and a pipeline device. A first inclined rod is arranged on the bottom plate, a first through hole, a second through hole, a first fixed block, second inclined rods, first cross rods, a second cross rod, first springs and a first baffle are arranged on the isolating frame, and a third through hole, a fourth through hole, a first sponge block, a second sponge block, a first filter screen and a first pipeline are arranged on the power cabinet. The exhaust device comprises a first support, a third inclined rod, a second support, a second pipeline, a draught fan, first connecting rods and a second connecting rod. The drying device comprises a drying box, a second filtering screen, a second baffle, a third filtering screen, third sponge blocks, a fourth filtering screen, second springs, a fifth filtering screen, a cover plate and fixed frames. The pipeline device comprises a third pipeline, a valve and fixed rods. According to the dehumidification device, the appropriate temperature in the power cabinet can be kept, and the humidity in the power cabinet can be effectively reduced.