Medulla biopsy slice hematopoiesis cell characteristic recognizing method

A technology of bone marrow cells and hematopoietic cells, applied in the field of image processing, can solve the problems of personnel fatigue, error and high intensity

Inactive Publication Date: 2008-10-01
SHANGHAI JIAO TONG UNIV
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Problems solved by technology

[0004] The purpose of the present invention is to address the deficiencies of the prior art, to provide a method for identifying the characteristics of hematopoietic cells in bone marrow biopsy slices, so as to solve the problems of personnel fatigue and errors caused by the original id

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  • Medulla biopsy slice hematopoiesis cell characteristic recognizing method
  • Medulla biopsy slice hematopoiesis cell characteristic recognizing method
  • Medulla biopsy slice hematopoiesis cell characteristic recognizing method

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Embodiment Construction

[0019] The embodiments of the present invention are described in detail below in conjunction with the accompanying drawings: this embodiment is implemented on the premise of the technical solution of the present invention, and detailed implementation methods and specific operating procedures are provided, but the protection scope of the present invention is not limited to the following the described embodiment.

[0020] The cell slices used in the embodiments are derived from bone marrow biopsy hematopoietic cell slices. The whole implementation process is as follows:

[0021] 1. Establish a computer graphical interface (GUI). Computer Graphics Interface (GUI) is the abbreviation of Graphical User Interface, that is, Graphical User Interface. To be precise, GUI is the visual experience and interactive operation part of screen products. Since the image processing and recognition parts of the present invention all adopt the mathematical processing software MATLAB, the designed...

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Abstract

A feature identifying method for marrow biopsy slice hematopoietic cell of the field of image process technology, the step is following: the first step: processing t eh read, detection and data storage for the marrow cell biopsy slice at the interface window; the second step: diving the area for the integral marrow cell biopsy slice according to the size of the cells to distinguish the cells in the different area and processing counting, locating the position of the cell and processing pre-diving for the build of the last three-dimensional model; the third step, uses the canny operator to process edge detection for the marrow cell biopsy slice, and separating the individual cell from the cell set of the integral slice; the fourth step, using the grey histogram to process grey treatment for the marrow cell biopsy slice, and distinguishing the proportion that the cell accounting for the divided grid via the grey grade of the chromosome cell. The invention solves the exhaustion of the stuffs caused by the original identification and the error problems, and enhances the precision of the cell feature identification.

Description

technical field [0001] The invention relates to a method in the technical field of image processing, in particular to a method for identifying hematopoietic cell features of a bone marrow biopsy section. Background technique [0002] Bone marrow biopsy (bone marrow biopsy) is a science that has made breakthrough progress in the past 10 years at home and abroad, and is the "gold standard" for clinical diagnosis of blood diseases and judgment of the progress or remission of bone marrow lesions. This method mainly relies on experienced pathologists to identify the number and location of abnormal cells in each microscopic field of view. The intensity of manual analysis is high, operators are prone to fatigue, and human errors are inevitable. Therefore, it is necessary to develop a computer-aided diagnosis model. [0003] Through the retrieval of prior art documents, it is found that Pu Quan and Yang Meiru (Color Atlas of Bone Marrow Histopathology in Hematological Diseases. Sha...

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Application Information

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IPC IPC(8): G01N15/10G01N33/48G01N21/84G06T7/60
Inventor 胡洁李晟石军王伟明彭颖红
Owner SHANGHAI JIAO TONG UNIV
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