Unlock instant, AI-driven research and patent intelligence for your innovation.

Chinese medicinal composition for treating arthritic and its preparation method

A composition and arthritis technology, applied in the field of traditional Chinese medicine composition and its preparation, can solve the problems of large side effects, multiple contraindications, difficult long-term use and tolerance of patients

Active Publication Date: 2011-10-19
JIANGSU KANION PHARMA CO LTD
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Anti-inflammatory and analgesic drugs and non-steroidal steroid drugs are mostly used, which have large side effects and many contraindications, and are difficult for patients to take and tolerate for a long time

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Chinese medicinal composition for treating arthritic and its preparation method
  • Chinese medicinal composition for treating arthritic and its preparation method
  • Chinese medicinal composition for treating arthritic and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1 ointment

[0041] [Prescription] Yanhusuo 107.5g Chuanxiong 86g Clematis 86g Fangfeng 107.5g Zanthoxylum bungeanum 107.5g Achyranthes bidentata 86g Carbomer 20g Triethanolamine 16g Glycerin 100g

[0042] [Preparation method] Zanthoxylum bungeanum, Rhizoma Chuanxiong, add 10 times the amount of water to distill and extract the volatile oil for 8 hours, and collect the distilled aqueous solution in another device; add 10 times the amount of water to extract the medicinal residues for 1 hour, combine the extract with the distilled aqueous solution, filter, and the filtrate Standby: Yanhusuo, Achyranthes bidentata, and Clematis clematis add 10 times of 70% ethanol to heat and reflux to extract twice, each time for 1 hour, combine the extracts, filter, recover ethanol, combine with the filtrate of the above-mentioned water extraction, and concentrate to relative density 1.20 ~ 1.25 (25 ℃) extract.

[0043] Mix the volatile oil and the extract evenly to obtain a...

Embodiment 2

[0044] Example 2 Gel

[0045] [Prescription] Yanhusuo 107.5g, Chuanxiong 86g, Clematis 86g, Shenjincao 107.5g, Speranthum 107.5g, Passepartout 86g, Pittoga bark 107.5g, Fangfeng 107.5g, Zanthoxylum bungeanum 107.5g, Achyranthes bidentata 86g, menthol 3.6g, borneol 7.2g, carbomer 20g triethanolamine 16g glycerin 100g

[0046] [Preparation method] Zanthoxylum bungeanum, Rhizoma Chuanxiong, add 10 times the amount of water to distill and extract the volatile oil for 8 hours, and collect the distilled aqueous solution in another device; add 10 times the amount of water to extract the medicinal residues for 1 hour, combine the extract with the distilled aqueous solution, filter, and the filtrate Standby: Yanhusuo, Shenjincao, Tougucao, Passepartout, Pittosporum, Achyranthes bidentata, Clematis clematis plus 10 times the amount of 70% ethanol, heated and refluxed twice, 1 hour each time, combined extracts, filtered , recover ethanol, combine with the filtrate of the above-mentioned...

Embodiment 3

[0048] Example 3 Tablet

[0049] [Prescription] Yanhusuo 107.5g, Chuanxiong 86g, Clematis 86g, Fangfeng 107.5g, Zanthoxylum bungeanum 107.5g, Achyranthes bidentata 86g

[0050] [Preparation method] The above six flavors, add 10 times of 60% ethanol to reflux extraction twice, each time for 1-2 hours, combine the ethanol extracts, filter, recover ethanol, and concentrate to extract with a relative density of 1.20-1.25 (25°C). Paste for later use; add 10 times the amount of water to the dregs, heat and reflux to extract twice, each time for 1 to 2 hours, combine the extracts, filter, concentrate under reduced pressure to a solution with a relative density of 1.10 to 1.20 (25°C), add ethanol to make the alcohol concentration to 80%, stand still for 12-36 hours, separate the alcohol precipitation supernatant, recover ethanol, and concentrate to an extract with a relative density of 1.20-1.25 (25°C). Combine the two extracts to obtain a mixed extract, add an appropriate amount of ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a Chinese medicine composite for curing arthritis. The composite mainly comprises the following raw materials by weight proportion: 20-200 portions of fumitory, 10-160 portions of szechuan lovage rhizome, 10-160 portions of clematis root, 20-200 portions of divaricate saposhnikovia root, 20-200 portions of pricklyash berry and 10-160 portions of achyranthes. The invention also discloses a method for preparing external and oral preparations. Pharmacodynamic experiments prove that the composite has strong analgesic effect and can reduce the response intensity of inflammation and the cartilage injury of knee osteoarthritis.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition with a therapeutic effect on arthritis and a preparation method thereof. Background technique [0002] Modern medicine divides osteoarthritis into two categories: one is primary osteoarthritis related to endocrine disorders in middle-aged and elderly people; the other is secondary osteoarthritis caused by local joint damage, inflammation or chronic strain. arthritis. Both have degeneration and degeneration of articular cartilage, bone hyperplasia at the edge of the joint, joint pain, limited mobility, stiffness and deformation as the main clinical features. [0003] Traditional Chinese medicine believes that the pathogenesis of osteoarthritis mainly has the following two modes: (1) Deficiency causes disease: the patient is weak endowed, or is old or seriously ill, resulting in the loss of essence, kidney qi, and bone insuffi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/758A61P19/02A61K31/045
Inventor 孙树椿肖伟张军戴翔翎凌娅王振中尚强刘涛
Owner JIANGSU KANION PHARMA CO LTD
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More