Novel vaginal micro-ecological appraisement system, reagent kit for appraising vaginal micro-ecology

A technology of microecology and kit, which is applied in the field of medical microecology, can solve the problems of no clear guiding significance in the diagnosis of vaginal inflammation, and achieve the effects of convenient application, simple operation method, and simple sample sampling

Inactive Publication Date: 2008-10-29
廖秦平 +1
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  • Application Information

AI Technical Summary

Problems solved by technology

Only in 1991, NugentPR, KrohnMA, and HillerSL put forward the Nugent score for vaginal flora through a large number of precise comparative experiments, which is used to diagnose BV, which has become the gold standard for laboratory diagnosis of BV, but there is no clear guidance for the diagnosis of other vaginal inflammations significance
As far as the domestic situation is concerned, almost no clinical hospitals really use Nugent score to guide clinical work

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Embodiment 1 test sample carries out the evaluation of following three aspects respectively

[0049] 1. Bacterial status:

[0050] 1. Normal flora: Gram-positive large bacteria are the dominant bacteria, the density is +~++, and the diversity is +~++.

[0051] 2. Bacterial flora imbalance: It should be considered comprehensively according to the density, diversity, dominant bacteria and clinical manifestations. specifically,

[0052] (1) Bacteria inhibition: All bacteria are reduced, showing no dominant bacteria, density is +, and diversity is +;

[0053] (2) Gram-positive cocci are the dominant bacteria:

[0054] The density and diversity are ++~+++. If there are no symptoms, the acidic environment of the vagina can be restored and the growth of Lactobacillus is mainly helped. If the density and diversity are +++~++++ and there are certain symptoms , application of antibiotics mainly against Gram-positive cocci;

[0055] (3) Gram-positive small bacilli are dominan...

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Abstract

The invention relates to the field of the medical microecology, in particular to a new vaginal microecological evaluation system and a reagent kit used for measuring and evaluating the vaginal microecology; the vaginal microecological system of the invention comprises the evaluating items that: the intensity of flora, the diversity of flora, dominant bacterium and reason bacterium; by using the system of the invention, three vaginal inflammations of BV, VVC and trichomoniasis which are common in clinic can be diagnosed fast at one time, and the problem existed in the vaginal microenvironment of patients with vaginal inflammation can be found; the most important is that microecological evaluation can be carried out for the patients with vaginal inflammation which comprises symptoms of increasing leucorrhea and pruritus vulvue, etc. without special pathogenic bacteria in the current clinic and is hard to diagnose by the existing method, the clinic drug is guided and evaluation is prognosed, thus achieving the purpose of guiding the clinical treatment.

Description

technical field [0001] The invention relates to the field of medical microecology, in particular to a new vaginal microecology evaluation system and a kit for evaluating vaginal microecology. Background technique [0002] Microecology is a new science. With the rapid development of science and technology in recent years, medical microecology has become an independent marginal subject and has been paid more and more attention by people. In 2001, as a branch of microecology, infection microecology was formally proposed. Subsequently, microecological research on female reproductive tract infection has gradually attracted attention. From the perspective of microecology, vaginal infection is vaginal microecological dysbiosis, and its main manifestation is the imbalance of vaginal flora. More than 20 kinds of microorganisms can be isolated from the vaginal discharge of healthy women, and they form a dynamic micro-ecological balance of mutual restraint, coordination and mutual co...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/48G01N21/84G01N33/50C12Q1/04C12Q1/25
Inventor 廖秦平刘朝晖
Owner 廖秦平
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