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Novel medicinal bottle stopper for lyophilized powder formulation

A technology of freeze-drying bottle stoppers and bottle stoppers, which is applied in the field of bottle caps, can solve the problems of not being able to meet the freeze-drying effect of freeze-dried powder injections, and achieve the effects of simple structure, high machine efficiency and convenient use

Inactive Publication Date: 2013-08-21
应城市恒天药业包装有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing medicinal bottle cap structure is relatively simple, as figure 1 The structure shown is generally a common one-time molding structure, which has the advantages of good airtightness, but it cannot meet the conditions of good freeze-drying effect and vacuum rapid aseptic packaging required for the production of freeze-dried powder injections

Method used

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  • Novel medicinal bottle stopper for lyophilized powder formulation
  • Novel medicinal bottle stopper for lyophilized powder formulation
  • Novel medicinal bottle stopper for lyophilized powder formulation

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Embodiment Construction

[0010] The present invention will be further described below in conjunction with the accompanying drawings:

[0011] like figure 2 , image 3 As shown, the present invention includes a bottle cap 1 and a bottle stopper 2, and four circular ventilation grooves 3 are evenly opened on the periphery of the bottle stopper 2. like Figure 4 As shown, the center of the bottle stopper has a circular hole 4; the outer wall of the bottle stopper is provided with protruding teeth 5, and the neck of the bottle stopper is provided with a 3° guide angle.

[0012] In the production process of freeze-dried powder injection, the bottle cap is firstly covered on the medicine bottle to the convex teeth 5. At this time, the medicine bottle is in a semi-sealed state, and the water vapor can evaporate from the four circular ventilation grooves 3, so that both The hygiene of the medicinal liquid is ensured, and the water vapor can be quickly evaporated, thereby shortening the freeze-drying time....

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Abstract

The invention relates to a bottle cap, in particular to a novel medical freeze-dried bottle stopper, which comprises a bottle stopper of which a center is provided with a round hole, and is characterized in that the periphery of the bottle stopper is uniformly provided with four round vent grooves, an outer wall of the bottle stopper is provided with double wedges, and a neck of the bottle stopper is provided with a 3 DEG guide angle. The novel medical freeze-dried bottle stopper has the advantages of simple structure and convenient use, can ensure that a packaging bottle has good air tightness, has the advantages of good freeze-drying effect and high production efficiency during production and packaging processes of freeze-dried powder injection, is favorable for the quick vacuum aseptic packaging of medicines, and improves the quality of products and the efficiency.

Description

technical field [0001] The invention relates to a bottle cap, in particular to a novel medicinal freeze-dried bottle stopper. Background technique [0002] Existing injections and powder medicines are generally bottled, especially freeze-dried powder injections are generally bottled according to national pharmaceutical product standards, and are sealed and stored with rubber caps. The production of freeze-dried powder injection is generally to freeze-dry the medicinal liquid containing the active ingredients of the medicine and then carry out vacuum aseptic packaging, and the production process is generally very long. For example, the production process of a certain product is as follows: first, cool down for 2 hours, then drop the temperature to -40°C, and maintain this temperature for about 6 hours; then gradually increase the temperature to 25°C. During this process, a vacuum state is required, and a vacuum of about 30-35Pa is required. It takes about 48 hours; the freez...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61J1/00
Inventor 石雄安夏汉桥丁安华
Owner 应城市恒天药业包装有限公司
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