Fermentation pharmacy product quality soft measurement method based on GP learning model building
A soft measurement and product technology, which is applied in the field of soft measurement of fermentation and pharmaceutical product quality, can solve the problems of low measurement accuracy and low modeling accuracy.
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[0037] The present invention will be further described below in conjunction with the accompanying drawings.
[0038] refer to Figure 1 ~ Figure 4 , a soft-sensing method for the quality of fermented pharmaceutical products based on GP learning modeling, the steps of the specific method are as follows:
[0039] 1) Collect a batch of process history data sets L of the fermentation process.
[0040] The data set L is composed of no more than 200 data samples {x, y} at the acquisition time, where x is the generalized input vector of the model, and its composition depends on the nonlinear model form adopted on the one hand (such as the serial-parallel structure ), on the other hand also depends on the qualitative process knowledge of biochemical reactions, reaction kinetics, etc. Generally, it is sufficient to take x as a combination of measurable conventional process variables and their delays.
[0041] y is the quality vector to be predicted, that is, the present invention ca...
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