Method and tool for drying hard substrate biological chips

Abstract

The invention discloses a method for drying a hard-substrate biological chip and a drying tool thereof. The method comprises the following technical proposal: (1) the chip drying tool is started; temperature is set between 22 and 37 DEG C and is balanced for 8 to 15 minutes; (2) the hard-substrate biological chip is put to a mould of the drying tool; the centrifugal rotational speed is between 2,000 and 5,000 rmp; and the hard-substrate biological chip is subjected to centrifugal rotation for 5 to 40 minutes. The chip drying tool used in the method for drying the hard-substrate biological chip comprises a shell, an inner liner and a top cover; a motor is arranged between the shell and the inner liner; a rotating shaft of the motor runs through the liner wall of the inner liner, and extends into a chamber of the inner liner; the rotating shaft of the motor is connected with a rotary arm; two ends of the rotary arm are connected with a mould bracket respectively; a mould is arranged on each mould bracket; the mould is provided with densely distributed macropores; and the macropores run through the bottom of the mould through small pylomes running through the bottom. The periphery of the inner liner is provided with a temperature control module. Through the chip drying tool and the matched mould, the drying method utilizes centrifugal force to firstly fully throw closed liquid remained on the surface of the chip off the chip and fully evaporate less moisture remained on the surface of the chip under the centrifugal vacuum environment in order that the chip achieves the drying effect.

Description

technical field

[0001] The invention relates to a drying method for a hard substrate biochip and a drying tool thereof, belonging to the technical field of biochips. Background technique

[0002] The emergence of biochip technology has made it possible to study thousands of genes and gene products in parallel in one experiment. The advantages of biochip technology lie in high detection sensitivity, low sample consumption, and high-throughput analysis. As a unique method for gene expression analysis, sequence analysis, clinical diagnosis, drug discovery, and drug screening, biochip technology has attracted worldwide interest. At present, hard-matrix biochips are still in the laboratory stage, and there is no hard-matrix biochip for industrial mass production. The production efficiency of traditional manual drying methods is low, and there is no drying method applied to industrial-scale production of hard-matrix biochips. Contents of the invention

[0003] The technical pro...

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