Recombinant rubella virus protein and uses thereof
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- 北京英诺特生物技术股份有限公司
- Publication Date
- 2009-08-19
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Abstract
Description
technical field
[0001] The invention relates to the fields of genetic engineering, vaccine development, diagnostic reagents and the like, in particular to a recombinant rubella virus protein and its application. Background technique
[0002] Rubella virus is the only member of the genus Rubellavirus in the Togaviridae family. The spherical rubella virus (RUBELLA VIRUS, RUV) is the pathogen of rubella, and humans are its only host. Rubella is an acute respiratory infectious disease with fever, respiratory tract sputum and rash as the main symptoms. Rubella virus infection in pregnant women, especially in early pregnancy, can lead to fetal congenital rubella syndrome (CONGENITAL RUBELLASYNDROME, CRS). Rubella and CRS occur all over the world, and the infection rate is high in Asia. After pregnant women suffer from rubella, especially within the first 3 to 4 months of pregnancy, rubella virus can invade the placenta and infect the fetus, causing congenital rubella as high as ...