Use of particular cationic polymers as anti-oxidant or anti-radical agents

A scavenger and antioxidant technology, applied in the application field of specific cationic polymers as antioxidants or free radical scavengers, can solve the problems of limited effect, unfavorable, ordinary cosmetic effect, etc., to improve free radical scavenging and/or or antioxidant effect

Inactive Publication Date: 2009-09-16
LOREAL SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore their cosmetic effects are usually mediocre or sometimes even unfavorable
[0005] Ultimately, their effectiveness is often limited, especially with regard to oxidation of the composition

Method used

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  • Use of particular cationic polymers as anti-oxidant or anti-radical agents
  • Use of particular cationic polymers as anti-oxidant or anti-radical agents
  • Use of particular cationic polymers as anti-oxidant or anti-radical agents

Examples

Experimental program
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Effect test

Embodiment Construction

[0104] Evaluation of polymers of the invention with respect to UVA oxidative stress induced on keratinocytes Antioxidant / free radical scavenging activity

[0105]Techniques for assessing photoprotection were performed according to known methods (J. of Photochemistry and Photobiology B: Biology 57 (2000) 102-112 TOBI et al.: Glutathione modulates the level of free radicals produced in UVA irradiated cells). The technique uses a fluorescent probe, a marker for intracellular spherical oxidative stress, 2'-7'-dichloro-fluorescein diacetate (DCFH-DA).

[0106] principle

[0107] The use of DCFH-DA as a marker of oxidative stress depends on its physicochemical properties. They are nonpolar and nonionic molecules capable of diffusing through cell membranes. Once inside the cell, DCFH-DA is hydrolyzed by intracellular esterases to non-fluorescent compounds: DCFH or 2,7-dichlorofluorescein. In the presence of reactive oxygen species, DCFH is rapidly oxidized to highly fluorescen...

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Abstract

Use of particular cationic polymers as anti-oxidant or anti-radical agents. The invention relates to application of a quaternary diammonium polycondensate comprising repeat units corresponding to the formula (I), and the invention is able to reduce hair degradation when applying oxide composition.

Description

technical field [0001] The present invention relates to the use of certain cationic polymers as antioxidants or free-radical scavengers, especially in cosmetic compositions, such as hair coloring compositions. Background technique [0002] The use of antioxidants and / or free radical scavengers in cosmetic compositions to combat degradation of the composition itself or of the substrate on which they are applied is known. In particular, the use of antioxidants or free radical scavengers is known to reduce hair damage when applying hair compositions. [0003] For example, patent application WO2004 / 087086 describes a compound containing less than or equal to 10 -14 m 2 / s diffusion constant of free radical scavenging compounds in cosmetic compositions. A number of radical scavenging compounds corresponding to this definition are cited. [0004] Antioxidants or free radical scavenging compounds currently used are sometimes unstable in cosmetic compositions or on the substrate...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/84A61Q5/10
CPCA61K2800/522A61K8/84A61Q5/10
Inventor J·-M·阿斯乔恩D·W·坎内尔
Owner LOREAL SA
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