Drug composition with the effect of anti-lung cancer and application in preparing anti-lung cancer drug

Abstract

The invention relates to a drug composition with the effect of anti-lung cancer and an application in preparing anti-lung cancer drug; the raw materials of the drug are as follows by weight portions: 10 to 30 of common selfheal fruit-spike, 10 to 50 of spreading hedyotis herb, 10 to 50 of hairyvein agrimonia herb and bud, 10 to 30 of yerbadetajo herb and 6 to 20 of dogwood. The drug extract is prepared by the following method which comprises the steps of: (1) extracting with 75 percent to 95 percent of alcohol for 1 to 4 times with 1 to 3 hours for each time; (2) carrying out extraction to the drug dreg extracted by the step (1) with 50 percent to 75 percent of alcohol for 1 to 4 times with 1 to 3 hours for each time; (3) combining the extracts of the (1) and (2), recovering the alcohol, reducing pressure and concentrating to obtain macroporous absorption resin column on the concentrated solution, using 40 percent to 60 percent of alcohol for elution to obtain extract I and using 70 percent to 90 percent of alcohol for elution to obtain extract II; and (4) mixing the extract I and the extract II to obtain active components. The application of the drug composition in preparing the drug for anti-lung cancer has stronger capacity to inhibit the proliferative activity of human lung cancer cell SPC-A-1.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a pharmaceutical composition with an anti-lung cancer effect, and an application of the pharmaceutical composition in preparing anti-lung cancer drugs. Background technique [0002] Lung cancer is one of the most common malignant tumors in the world today. Its incidence and mortality rate have ranked first among common tumors, and it has become a major killer of human health. In recent years, the morbidity and mortality of lung cancer have been on the rise from a global perspective, and are increasing at a rate of 0.5% per year. In my country, lung cancer is the most common malignant tumor in cities. In the past 20 years, the mortality rate of lung cancer in cities has more than doubled. With the increase in the number of young people smoking in my country, the incidence and mortality of lung cancer in my country will continue to rise in the next century. At present...

AI Technical Summary

Problems solved by technology

At the same time, most anti-lung cancer compound prescriptions in clinical practice are mostly used as decoctions, which are inconvenient to carry and take; or directly made into oral preparations after extracting extracts, the extraction rate of active ingredients is not high, the preparations are thick, and the quality is difficult to control, which cannot meet international standards. and domestic market demand

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