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Medicament for curing urticaria

A technology of urticaria and medicine, which is applied in the field of medicine for treating urticaria, can solve problems such as difficult treatment, stubborn clinical manifestations, complicated pathogenesis, etc., and achieve the effect of safe taking and less toxic and side effects

Inactive Publication Date: 2009-12-23
三普药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disease is a common and frequently-occurring disease in skin diseases. Due to the complex etiology of the disease, it is difficult to treat, especially chronic urticaria. The clinical manifestations are stubborn and persistent, and there is no ideal drug so far.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0008] Take the raw materials according to the following weight ratio:

[0009] Astragalus 15kg, Poria cocos 15kg, Fangfeng 17kg, Atractylodes macrocephala 17kg, Dabupi 17kg, Morus alba 7kg, Chenpi 4kg, Guizhi 8kg

[0010] The preparation method is as follows:

[0011] A. Take tangerine peel, windproof, Atractylodes macrocephala, cinnamon sticks and other four raw materials to extract volatile oil, set aside, and collect the water decoction in another device;

[0012] B. The dregs, Poria cocos, Cortex Mori, and Dabupi are decocted twice, each time for 2.5 hours, and the decoction is combined with the decoction after oil extraction such as tangerine peel, filtered to remove residue, and the filtrate is concentrated to a relative density of 1.10 (i.e. 1.1 kg / liter) of the clear cream, add ethanol to make the alcohol content reach 55%, stir evenly, let stand overnight, collect the supernatant, and the precipitation is stirred once with 55% ethanol, and the washing liquid and the...

Embodiment 2

[0022] Take the raw materials according to the following weight ratio:

[0023] Astragalus 26kg, Poria cocos 26kg, Fangfeng 7kg, Atractylodes macrocephala 7kg, Dabupi 7kg

[0024] Mulberry bark 17kg Chenpi 6kg Guizhi 4kg

[0025] The preparation method is as follows:

[0026] A. Take tangerine peel, windproof, Atractylodes macrocephala, cinnamon sticks and other four raw materials to extract volatile oil, set aside, and collect the water decoction in another device;

[0027] B. Add water to decoct the dregs of Poria cocos, Cortex Morus alba, and Dabupi 4 times, each time for 0.5 hours, combine the decoction and tangerine peel and other decoctions after oil extraction, filter to remove residue, and concentrate the filtrate to a relative density of 1.20 (i.e. 1.2 kg / liter) of the clear cream, add ethanol to make the alcohol content reach 65%, stir well, let stand overnight, collect the supernatant, and the precipitation is stirred once with 65% ethanol, and the washing liquid ...

Embodiment 3

[0034] Take the raw materials according to the following weight ratio:

[0035] Astragalus 20kg, Poria cocos 15kg, Fangfeng 12kg, Atractylodes macrocephala 15kg, Dabupi 7kg, Morus alba 7kg, Chenpi 12kg, Guizhi 12kg

[0036] The preparation method is as follows:

[0037] A. Take tangerine peel, windproof, Atractylodes macrocephala, cinnamon sticks and other four raw materials to extract volatile oil, set aside, and collect the water decoction in another device;

[0038] B. The dregs, Poria cocos, Cortex Morus albicans, and Dabupi are decocted with water for 4 times, each time for 0.5 hours, combined with the decoction and dried tangerine peel decoction after oil extraction, filtered to remove residue, and the filtrate is concentrated to a relative density of 1.20 (i.e. 1.2 kg / liter) clear paste, add ethanol to make the alcohol content reach 65%, stir evenly, let stand overnight, collect the supernatant, precipitate with 65% ethanol and stir wash once, combine the washing liqui...

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PUM

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Abstract

The invention belongs to the technical field of pharmaceuticals and particularly relates to a medicament for curing urticaria. The medicament is characterized by including the following materials by mass percent: 15-26% radix astragali, 15-26% of poria cocos, 7-17% of radices sileris, 7-17% of Chinese atractylodes, 7-17% of pericarpium arecae, 7-17% of white mulberry root-bark, 4-12% of tangerine peel and 4-12% of cassia twig. The preparation technology of the medicaments comprises the steps of: extracting volatile oil from the tangerine peel, the radices sileris, the Chinese atractylodes and the cassia twig; mixing medicament dregs with the other three materials for decoction extraction; and carrying out ethanol reflux extraction on the radix astragali and then preparing extractum or extractum powder thereof together with the volatile oil into solid, liquid or semi-solid medicament products acceptable on pharmacy. Proven by clinical test, the medicament has a curative rate of 23% for urticaria, a total effective rate of 72.3%, pharmaceutical effect obviously better than the existing medicament, low toxic and side effects, and safe taking.

Description

1. Technical field: [0001] The invention belongs to the technical field of medicines, in particular to a medicine for treating urticaria. 2. Technical background: [0002] Urticaria is caused by external attack of rheumatism. Symptoms include white rash, swelling, itching, onset and disappearance, aversion to wind, and spontaneous sweating. This disease is common disease, frequently-occurring disease in skin disease, because the pathogenesis of this disease is complicated, and treatment is more difficult, especially chronic urticaria, and clinical manifestation is obstinate, persistent, so far there is no ideal medicine. 3. Contents of the invention: [0003] The purpose of the present invention is to exist above-mentioned problem at prior art, and develop a kind of medicine that curative effect is better for the treatment of urticaria, this medicine is through hospital clinical trial research, and its cure rate reaches 23%, and total effective rate reaches 72.3%, and The...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61P17/00A61P37/08
Inventor 贺生玲牛蓉马俊仓
Owner 三普药业有限公司
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