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Composition for reducing blood pressure

A composition and plant technology, applied in the direction of drug combination, cardiovascular system diseases, organic active ingredients, etc., can solve problems such as unseen research data

Active Publication Date: 2011-05-04
北京化药科创医药科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] For the combination of the two drugs, there is no relevant research data

Method used

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  • Composition for reducing blood pressure
  • Composition for reducing blood pressure
  • Composition for reducing blood pressure

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Preparation of tablets (prescription of 1000 tablets)

[0036] Berberine 300g, gastrodin 100g, lactose 80g, povidone 15g, magnesium stearate 5g, 70% ethanol in proper amount;

[0037] Take raw materials and auxiliary materials, crush them through a 100-mesh sieve, mix berberine, gastrodin, and lactose evenly, use povidone previously dispersed in 70% ethanol as a binder, prepare soft materials, sieve to make granules, and dry at 60°C , whole grains, added magnesium stearate, compressed into 1000 tablets.

Embodiment 2

[0039] Preparation of capsules (prescription of 1000 capsules)

[0040] Berberine 400g, gastrodin 50g, starch 50g

[0041] Take raw materials and auxiliary materials, pulverize, mix evenly, fill in 1000 hard capsules, and obtain capsules.

Embodiment 3

[0043] Preparation of dropping pills

[0044] 20g of berberine, 5g of gastrodin, appropriate amount of the usual drop pill base in pharmaceuticals

[0045] The raw material medicine and the drop pill base are prepared into drop pills according to the preparation process of drop pills in pharmaceuticals.

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Abstract

The invention relates to a compound hypotensive preparation formed by raw medicines of berberine and gastrodin. The research of the invention proves that the combination of the berberine and the gastrodin has the blood pressure reduction effect which is obviously better than that of the berberine or the gastrodin which is singly used.

Description

technical field [0001] The invention relates to an antihypertensive composition, in particular to an antihypertensive composition composed of plant extract components gastrodin and berberine, belonging to the field of pharmaceutical preparations. Background technique [0002] Gastrodia elata belongs to the Orchidaceae plant. It is a precious medicinal material in my country. It is pungent, warm, non-toxic, and has the function of calming the liver and calming the wind. It is often used for headaches, dizziness, and numbness of the body. Its chemical components include gastrodin and gastrodin , vanillyl alcohol, gastrodin, p-hydroxybenzaldehyde, citric acid, succinic acid, etc. Among them, the effective monomer component with the highest content of active ingredients is gastrodin, which has various pharmacological activities, such as sedative hypnosis, anticonvulsant, Pain relief, protection of hypoxic brain cell damage, reduction of peripheral vascular resistance, etc., are co...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7034A61K31/4375A61P9/12
Inventor 关屹闫冬
Owner 北京化药科创医药科技发展有限公司
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