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Preparation method of hypericum perforatum extract

A technology of Hypericum perforatum and extract, applied in the field of medicine to achieve the effects of improving sleep, simple preparation method and restoring self-confidence

Inactive Publication Date: 2010-01-20
RHK GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

There are few reports on the preparation method of Hypericum perforatum extract

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  • Preparation method of hypericum perforatum extract

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Effect test

Embodiment 1

[0020] refer to figure 1 , the preparation method steps of Hypericum perforatum extract in the present embodiment are: (1) medicinal material pretreatment: remove weeds from the above-ground part of Hypericum perforatum in full flowering stage, cut into the length of 1cm; (2) Extract: use 90% by weight % of ethanol, reflux extraction for 3 times, the first reflux extraction for 1 hour, wherein the amount of medicinal materials was 5 times that of the solution, and the second to third reflux extraction for 1.5 hours, wherein the amount of medicinal materials was 7 times that of the solution, combined The above extract is filtered, and the ethanol is recovered under reduced pressure until the alcohol content is 30%. The mass ratio of the medicinal material and the solution in the filtrate is 1:7, and it is left to stand. After clarification, filter to obtain the filtrate; (3) put it on the column Elution: Pass the obtained filtrate through the treated macroporous resin, and when...

Embodiment 2

[0023] refer to figure 1 , the preparation method steps of Hypericum perforatum extract in the present embodiment are: (1) medicinal material pretreatment: remove weeds from the above-ground part of Hypericum perforatum in full flowering stage, cut into the length of 1.5cm; (2) extract: use mass percentage as 60% ethanol, reflux extraction for 5 times, the first reflux extraction for 2 hours, wherein the amount of medicinal materials is 7 times that of the solution, the second to fifth reflux extraction for 1 hour, wherein the amount of medicinal materials is 4 times that of the solution, Combine the above extracts, filter, and reclaim ethanol under reduced pressure until the alcohol content is 55%, the mass ratio of the medicinal materials and the solution in the filtrate is 1:8, let stand, and after clarification, filter to obtain the filtrate; (3) Column elution: pass the obtained filtrate through the treated macroporous resin, and when the liquid level of the filtrate is 3...

Embodiment 3

[0026] refer to figure 1 , the preparation method step of the Hypericum perforatum extract in the present embodiment is: (1) medicinal material pretreatment: remove the weeds from the above-ground part of Hypericum perforatum in full flowering stage, cut into the length of 2cm; (2) extract: use 70% by weight % of ethanol, reflux extraction 2 times, the first reflux extraction for 3 hours, wherein the amount of medicinal materials is 5 times the amount of the solution, the second reflux extraction for 2 hours, wherein the amount of medicinal materials is 8 times the amount of the solution, combined the above extraction Liquid, filtered, ethanol is recovered under reduced pressure until the alcohol content is 80%, the mass ratio of medicinal materials and solution in the filtrate is 1:7, let stand, after clarification, filter to obtain the filtrate; (3) column elution : the resulting filtrate flows through the treated macroporous resin, and when the liquid level of the filtrate ...

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Abstract

The invention discloses a preparation method of a hypericum perforatum extract, belonging to the field of medical technology. The preparation method comprises five steps of medicine material pre-treatment, refining, upper column elution, extraction and drying. The prepared hypericum perforatum extract can prevent and treat tristimania, regulate affective disorder and emotional dissonance, eliminate tension and dump, recover confidence and improve sleeping.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a preparation method of an extract. Background technique [0002] Depression is a serious mental disorder, and its incidence rate has leapt to the fourth among the top ten common diseases in the world. Experts predict that depression will rise to the second most common disease in the next 20 years. According to statistics, about 5-6% of the population suffers from depression to varying degrees, and the incidence of depression among the elderly is about 11-25%. With the accelerating pace of life, social pressure is increasing , my country's mental illness has reached 16 million people, and the incidence of depression is also increasing year by year. There are three main types of antidepressant drugs: tricyclic drugs, monoamine oxidase inhibitors (MAOIs) and selective 5HT reuptake inhibitors (SSRIs). Although these drugs do not have a relatively definite curative effe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P25/24
Inventor 谢圣明张廷璧杨崇琪
Owner RHK GROUP
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