Method for preparing biological organism optical bionic material and model prepared by thereof

A technology for biological tissue and biomimetic materials, applied in the field of preparation of biological tissue biomimetic materials, can solve the problems of complex preparation process and expensive equipment, and achieve the effects of easy operation, low cost, and time and cost saving.

Inactive Publication Date: 2010-06-09
BEIJING NORMAL UNIVERSITY
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its preparation process is relatively complex and the equipment is relatively expensive
Moreover, there are few rep

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for preparing biological organism optical bionic material and model prepared by thereof
  • Method for preparing biological organism optical bionic material and model prepared by thereof
  • Method for preparing biological organism optical bionic material and model prepared by thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0026] As mentioned above, the preparation process of solid biological tissue optical biomimetic materials is rarely disclosed, and there is still a lack of stable production methods for such materials and commercially available biological tissue biomimetic materials or models in China. Therefore, the present invention provides a preparation method of biological tissue optical biomimetic material.

[0027] According to literature reports, the absorption coefficient of biological tissue ranges from 0.1 to 10 cm -1 , the scattering coefficient ranges from 1 to 1000cm -1 . The present invention aims to provide a method for preparing biological tissue optical biomimetic material with any given optical constant within the above range and a biological tissue optical bionic model prepared by the method. The method comprises the following steps: firstly, a matrix resin is provided, and the matrix resin has a light transmittance greater than or equal to 80% when measured with a thin ...

Embodiment approach

[0044] According to one embodiment of the present invention, the matrix resin may be a curable resin, and preferably the curing time is in the range of 15-30 minutes, preferably about 20 minutes. The optimal curing time can be determined by simple experiments according to the nature of the light absorber and scattering agent added. Within the above curing time range, on the one hand, sufficient time can be provided for uniform dispersion operations such as stirring, and on the other hand, the sedimentation of the absorbing agent and / or scattering agent can be prevented, so as to obtain a biomimetic material with uniform optical properties.

[0045] The curable resin can be any suitable thermosetting resin, UV curable resin, room temperature curable resin, and the like. A room temperature curing resin is preferably used, wherein the curing agent and the accelerator are preferably added in an amount of 3-5 μL of curing agent: accelerator: 5-10 μL per gram of the room temperature...

Embodiment 1

[0069] Embodiment 1 prepares absorption coefficient μ a =5.0cm -1 , scattering coefficient μ s =20cm -1 Optical biomimetic model matrix resin:

[0070] The HR-8142 crystal resin produced by Changzhou Huarun Composite Materials Co., Ltd. was used as the matrix material of the bionic model. Its main components are unsaturated polyester and styrene with a weight ratio of 7:3, and the dynamic viscosity is 0.31-0.52Pa. s (25°C), the gel time is 5.0-9.0min (25°C), and the heat distortion temperature is ≥55°C.

[0071] Accelerator:

[0072] The HR-E5 type accelerator produced by Changzhou Huarun Composite Materials Co., Ltd. is used. Its main components are cobalt isooctanoate styrene and styrene in a weight ratio of 1:9, and the gel time is 7.0-13.0min (25C°).

[0073] Hardener:

[0074] The HR-M type curing agent produced by Changzhou Huarun Composite Materials Co., Ltd. is used. Its main components are methyl ethyl ketone peroxide and styrene in a weight ratio of 1:9 or 2:8,...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Absorption coefficientaaaaaaaaaa
Particle sizeaaaaaaaaaa
Dynamic viscosityaaaaaaaaaa
Login to view more

Abstract

The invention discloses a method for preparing a biological organism optical bionic material and a model prepared by thereof. The material has an absorbing coefficient within 0.1-10 cm<-1> and a scattering coefficient within 1-10000 cm<-1>. The method comprises the following steps of: A. providing matrix resin with the transmittance greater than or equal to 60% by measuring a thin plate with the thickness of 1.0 mm on a 600-1000 nm near-infrared light area; B. preparing an absorption body by mixing the matrix resin and an absorbing agent, and determining the value of an absorption constant Ka; C. preparing a scattering body by mixing the matrix resin and a scattering agent, and determining the value of a scattering constant Ks; D, preparing the biological organism optical bionic material according to the determined values of Ka and Ks. The invention has the advantages of simple process and convenient operation; and the prepared model has uniform and stable optical property, is easy to process into various shapes, and can be repetitively used.

Description

technical field [0001] The invention relates to a preparation method of a biological tissue bionic material, in particular to a preparation method of a biological tissue bionic material with any given optical constant. Background technique [0002] Studying near-infrared light (600-1000nm) imaging methods for early diagnosis of cancer is an important topic in biomedical optics at present, because imaging biological tissues with near-infrared light has the characteristics of non-destructive, living and real-time. In order to use near-infrared light for imaging, it is necessary to understand the interaction rules between near-infrared light and tissues, and this is an important field of research in the current academic circle. Only on the basis of understanding the basic law of the interaction between light and tissue can further imaging research be done. The organism itself is a living body that changes in real time. Any change in the external environment will change its ori...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C08L101/12C08J3/22C08L51/08C08K3/04C08K3/22
Inventor 孙萍杨润秋刘剑丁嘉琪张付强谢风华
Owner BEIJING NORMAL UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap