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Inflammation diminishing capsules prepared from baical skullcap root and golden thread and preparation method thereof

A technology for anti-inflammatory capsules and capsules, applied in the directions of capsule delivery, anti-inflammatory agents, digestive system, etc., can solve the problems of uneven content, long production cycle, easy damage, etc., and achieve good content uniformity, uniform loading difference, and production The effect of cycle shortening

Inactive Publication Date: 2010-07-07
JIANGXI BAISHEN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The traditional production process of Shuanghuang Xiaoyan Capsules has many extracts, and after mixing the extracts and powder, it is difficult to granulate, and secondary granulation and crushing are required, and the sieve is easily damaged; and the traditional process has a long production cycle and the product Particles are not uniform; the volume difference is not easy to control when the capsule is filled, and the content is not uniform

Method used

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  • Inflammation diminishing capsules prepared from baical skullcap root and golden thread and preparation method thereof
  • Inflammation diminishing capsules prepared from baical skullcap root and golden thread and preparation method thereof

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Embodiment Construction

[0014] The technological process of Shuanghuang Xiaoyan Capsules preparation of the present invention is:

[0015] 1. crush

[0016] Get Scutellaria baicalensis 257.1g and grind into fine powder;

[0017] 2. Decocting - extracting the decoction of Scutellaria baicalensis

[0018] (1) The first decoction: Weigh 171.5g of Scutellaria baicalensis into a multi-functional extraction tank, add water about 10 times the amount of medicinal materials, heat to boil, decoct for 3 hours, and take out the decoction.

[0019] (2) The second decoction: add about 10 times the amount of water to the dregs of the first decoction, heat to boil, decoct for 1 hour, and take out the decoction.

[0020] (3) The third decoction: add water about 10 times the amount of medicinal materials to the dregs decocted for the second time, heat to boil, decoct for 0.5 hour, and take out the decoction liquid.

[0021] (4) Filtration: Combine three decoctions, and filter the decoction with a 200-mesh stainless...

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Abstract

The invention discloses inflammation diminishing capsules prepared from baical skullcap root and golden thread and a preparation method thereof. The method is characterized in that a granulating process adopts spray drying one-step granulating technology, liquor is used as adhesive, the medicinal powder is blown to be stuck with the liquor together and directly prepared into dry grains with even size, and the dry grains are filled into capsules. The process of one-step granulating technology comprises the following steps: weighing a proper amount of baical skullcap root powder serving as an auxiliary material and feeding the baical skullcap root powder into a fluidized bed granulating chamber of a spray drying granulator, and blowing hot air into the fluidized bed granulating chamber to preheat the baical skullcap root powder; starting an air blower to make the air enter the granulating chamber through a filter device and a heat exchanger from an air inlet, make a negative pressure formed in the granulating chamber, and make the medicinal powder float up and down for preheating and drying; spraying a proportional quantity of medicinal extract concentrated solution to the granulating chamber through a spray nozzle to form fog drops, and agglomerating the fog drops and the baical skullcap root powder to form porous grains; blowing the hot air to dry the grains while spraying, and vibrating a powder catching bag at regular intervals; and repeating the operation till the specified amount of medicinal extract concentrated solution is completely sprayed. The method is suitable for the preparation and production of the inflammation diminishing capsules prepared from the baical skullcap root and the golden thread.

Description

technical field [0001] The invention relates to a Shuanghuang Xiaoyan capsule and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Shuanghuang Xiaoyan Capsule is a traditional Chinese medicine product made of Scutellaria chinensis and three needles (also known as Cihuanglian). Diarrhea, Dysentery Chronic dysentery, etc. [0003] Publication No. CN1709334 discloses a Shuanghuang Xiaoyan dispersible tablet and its preparation method, using three needles, Scutellaria baicalensis and polyvinyl alcohol as raw materials. Authorized notification number CN100341487 discloses a Shuanghuang Xiaoyan dripping pill for anti-inflammatory. The invention is an oral preparation of a pharmaceutical composition prepared from two traditional Chinese medicines such as three needles and Scutellaria baicalensis. Shuanghuang Xiaoyan Capsules have been included in the Chinese Pharmacopoeia. [0004] The traditional produ...

Claims

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Application Information

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IPC IPC(8): A61K36/539A61K9/48A61P29/00A61P11/04A61P1/12A61P31/04
Inventor 付志高
Owner JIANGXI BAISHEN PHARMA
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