The invention discloses a powder extruding device for medical tablets, which comprises a casing, a driving device, a first extrusion roller, a second extrusion roller, a rib, a scraper and a medicine feeding funnel, and a second extrusion funnel is arranged inside the casing. One extruding roller and the second extruding roller, the first extruding roller and the second extruding roller are arranged in parallel, and the described first extruding roller and the second extruding roller are arranged in parallel; In the process of being involved, the cutting edge between the adjacent ribs cuts the tablet, and the drug is squeezed again by the ribs and the first extrusion roller or the second extrusion roller, so that the tablet is powdered and granulated. Uniformity, improving the powder quality, the scraper scrapes off the powder adhered to the ribs, the first extrusion roller and the second extrusion roller, and finally the powder enters the frame, and the powder particles that do not meet the particle size requirements are filtered Net interception, the invention has simple structure, low manufacturing cost, good powder extrusion effect, and has good practical effects.