A kind of Xiaoer Qingrening traditional Chinese medicine granule

A technology of traditional Chinese medicine granules and children, which is applied in the direction of antipyretics, drug combinations, pharmaceutical formulas, etc., can solve the problems affecting the product quality of Xiaoer Qingrening granules, the quality of material powder, and the heat-sensitive components are easily damaged, so as to achieve the protection Destroyed, improved quality control, good fluidity effects

Active Publication Date: 2014-10-15
HENAN FURENTANG MEDICINES +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, in the national drug standard of Xiaoer Qingrening Granules, the preparation of precious animal powders such as antelope horns and buffalo horns uses ordinary crushing technology, which affects the powder quality of the materials, and the current preparation process is easy to cause the materials to soften and melt. , even discoloration, coking, etc., heat-sensitive components are easily damaged, difficult to dry, high hygroscopicity, poor fluidity, long drying time, uneven powder color, etc., which affect the product quality of Xiaoer Qingrening Granules
[0005] At present, in the national drug standard of Xiaoer Qingrening Granules, there is no content determination item recorded, only the TLC identification of baicalin in Scutellaria baicalensis is a quality control index, which increases chlorogenic acid in honeysuckle, baicalin in Scutellaria baicalensis and bilirubin in bezoar It is very necessary to improve the quality of Xiaoer Qingrening Granules by HPLC content determination of active ingredients such as

Method used

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  • A kind of Xiaoer Qingrening traditional Chinese medicine granule
  • A kind of Xiaoer Qingrening traditional Chinese medicine granule
  • A kind of Xiaoer Qingrening traditional Chinese medicine granule

Examples

Experimental program
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Effect test

Embodiment 1

[0014] Selection: 2.5g of antelope horn powder, 2.5g of bezoar, 300g of honeysuckle, 250g of baicalin, 250g of Radix Bupleurum, 350g of Radix Isatidis, 25g of concentrated buffalo horn powder, 0.5g of borneol, and an appropriate amount of apple flavor as raw materials for the traditional Chinese medicine composition of the present invention. The preparation method is as follows:

[0015] Take the antelope horns and buffalo horns of the formula amount and use the low-temperature ultra-fine pulverization technology to pulverize (temperature: -20°C, time: 50min, particle size: 600 mesh), wash and moisten the Bupleurum bupleuri in the formula amount, cut into thick slices, Add 8 times the amount of water, soak in warm (60°C) for 2 hours, extract the volatile oil, distill for 6.5 hours, filter the distilled aqueous solution, collect in another device, remove impurities from honeysuckle, scutellaria, and Radix Radix (scutellaria, Radix Radix) and mix well. Add water to decoct twice,...

Embodiment 2

[0035] Selection: 5g of antelope horn powder, 5g of bezoar, 600g of honeysuckle, 500g of skullcap, 500g of Radix Bupleuri, 700g of Radix Isatidis, 50g of concentrated buffalo horn powder, 1g of borneol, and an appropriate amount of apple essence are the raw materials of the traditional Chinese medicine composition of the present invention. The preparation method is as follows:

[0036] Take the antelope horns and buffalo horns of the formula amount and use the low-temperature ultrafine pulverization technology to pulverize (temperature: -15°C, time: 40min, particle size: 500 mesh), wash and moisten the Bupleurum bupleuri in the formula amount, cut into thick slices, Add 8 times the amount of water, soak in warm (50°C) for 2 hours, extract the volatile oil, distill for 6.5 hours, filter the distilled aqueous solution, and collect it in another device, remove impurities from honeysuckle, scutellaria baicalensis, and Radix Radix, slice Scutellaria baicalensis and Radix Radix, mix ...

Embodiment 3

[0040] Selection: 10g of antelope horn powder, 10g of bezoar, 1200g of honeysuckle, 1000g of Scutellaria baicalensis, 1000g of Radix Bupleurum, 1400g of Radix Radix, 100g of concentrated buffalo horn powder, 2g of borneol, and an appropriate amount of apple essence are the raw materials of the traditional Chinese medicine composition of the present invention. The preparation method is as follows:

[0041] Take the antelope horns and buffalo horns of the formula amount and use the low-temperature ultra-fine grinding technology to pulverize (temperature: -25°C, time: 50min, particle size: 600 mesh), wash and moisten the Bupleurum bupleuri in the formula amount, cut into thick slices, Add 8 times the amount of water, soak in warm (50°C) for 2 hours, extract the volatile oil, distill for 6.5 hours, filter the distilled aqueous solution, and collect it in another device, remove impurities from honeysuckle, scutellaria baicalensis, and Radix Radix, slice Scutellaria baicalensis and R...

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Abstract

The present invention disclosed a kind of children's Qing Rein Chinese medicine particles, which belong to the field of traditional Chinese medicine.It is made of gold and silver flowers, scutellaria baicalensis, Bupleurum, Banlangen, Antelope horn powder, beef, cattle horn concentrated powder, and borneol as raw materials., Improve the powder quality of the material; effectively protect the thermist component of spray drying technology, which is not destroyed, and overcomes the problems of traditional drying difficulties, large hygroscopicity, poor liquidity, long drying time, and uneven pink pink. In a short time, in a short timeInternal granules with good liquidity, low water content, and uniform size are consistent, which greatly improves the quality of Qing Ning Ning Granules.And to increase the measurement items of the content of drugs such as Huangpinyl, custodonin, tinyl flowers, and beef and bilirubin in the formula, so that the quality control of the children's clearing the Jining particles is significantly improved.After clinical application, the total effective rate reached 94.29%, and the significant efficiency reached 80%.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, which belongs to the field of traditional Chinese medicines, in particular to Xiaoer Qingrening traditional Chinese medicine granules. Background technique [0002] Acute upper respiratory tract infection in children is one of the common diseases in children, and its incidence rate accounts for the first place in pediatric diseases. The main symptoms are fever, cough, nasal congestion, runny nose, sore throat, headache, etc. If not treated in time, serious complications such as pneumonia, myocarditis, encephalitis, etc. will be life-threatening. Drug therapy is the main means of pediatric disease prevention and treatment. Since children are in the stage of rapid growth and development, the various systems and organs of the body are not fully developed, individual differences are large, tolerance is poor, side effects of Western medicine are large, and the symptoms are not cured. Med...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K36/539A61P29/00
Inventor 吴亚李精云丁红强朱成功孟庆乐黄占海方永霞杨蕾朱来峰付晓宁满喜霞罗琦马芳
Owner HENAN FURENTANG MEDICINES
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