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295 results about "Drug extraction" patented technology

Chinese medicinal preparation for treating facial chloasma and preparation method thereof

The invention relates to a Chinese medicinal preparation for treating facial chloasma, which is the medicinal preparation prepared from 77 raw material medicaments such as peach seed, safflower, danshen root, red paeony root and hawthorn fruit. The medicinal preparation is powder, tablets, pills, capsules, electuary or oral liquid. A preparation method of the Chinese medicinal preparation comprises the following steps of: (1) sieving and crushing the raw material medicaments; (2) sieving, and taking screening; (3) disinfecting and sterilizing to obtain medicinal raw powder; and (4) preparing the medicinal raw powder into tablets, granules, pills or capsules. The preparation method also can comprise the following steps of: (1) preparing the raw material medicaments into medicinal water extracting solution; (2) preparing the medicinal water extracting solution into the oral liquid; (3) drying, crushing and sieving the medicinal water extracting solution, taking screening, disinfecting and sterilizing to obtain medicinal extracting powder; and (4) preparing the medicinal extracting powder into tablets, granules, electuary or capsules. The Chinese medicinal preparation has a formula based on Chinese medicinal theory, and makes five internal organs healthy, and Yin and Yang balanced. The Chinese medicinal preparation mainly treats facial chloasma, freckles and facial pigmentation, treats hair loss caused by vitality stagnation and blood stasis, and has good curative effect on irregular cycles and infertility. The Chinese medicinal preparation is prepared from pure Chinese medicaments and has the advantages of diversiform formulations, convenient use, safety, reliability, no toxic or side effects, and suitability for long term usage.
Owner:卢速江

Method for preparing functional polymer material

The invention discloses a method for preparing a functional polymer material, and belongs to the field of fiber material and plastic processing. The invention aims at solving the shortcomings of low efficiency and high cost of carrying out functionalization on traditional polymer materials by blending and surface chemical grafting. The method disclosed by the invention comprises the following steps: acting an alternating electric field on functional material particles to be physically embedded on the surface of an extruded base material of the polymer material, carrying out chemical crosslinking and physical blending on a crosslinking group and the surface of the base material of the polymer material, and blowing cold air to the base material of the polymer material for curing or blowing cold air to the base material of the polymer material for curing after stretching to obtain the functional polymer material. The selection range of functional substances in the method disclosed by the invention is very wide, the utilization rate is high, the effect is good, the dosage is small, the preparation procedure of the material is short, and the efficiency is high, so that the method can be widely used in the fields of the textile and garment industry, plastic industry, environmental management, drug extraction and the like.
Owner:WUYI UNIV +1

Method for filtering and separating suspended maters from water and filtering device used in method

The invention relates to a method for filtering and separating suspended maters from water and a filtering device used in the method. According to the concrete technology, a filter screen of the filtering device is directly arranged in water flow in a water flow channel; the included angle a is formed between the filtering surface of the filter screen and the water flow direction of the surface of the filtering surface, wherein the included angle a can be an acute angle between 0 and 70 DEG or an obtuse angle between 110 DEG C and180 DEG; and the filter screen of the device and different water flow channels form different cross flow filtering systems. The method and device provided by the invention can be widely applied to lake blue-green algae, sewer liquid dung, sewage treatment plants and vegetable drug extraction.
Owner:郑向东

Lung clearing oral liquid preparation for treating viral pneumonia in Children and preparing method thereof

A Chinese medicine "Qingfei oral liquid" for treating baby's viral pneumonitis is prepared from 10 Chinese-medicinal materials including ephedra, gypsum, bitter apricot kernel, red sage etc through grinding and distilling bitter apricot kernel to obtain liquid, decocting its dregs along with others twice, concentrating, depositing in alcohol, taking supernatant, recovering alcohol, adding water, boiling, filtering, mixing with cane sugar solution and said distilled liquid, adding water, and sterilizing. Its advantage is higher curative effect.
Owner:SICHUAN JISHENGTANG PHARMLS

Niuhuangshangqing soft capsule and preparation method thereof

The invention relates to a Niuhuangshangqing soft capsule and a preparation method thereof, as well as a quality control method of capsule contents. The Niuhuangshangqing soft capsule comprises contents and capsule shell. The contents include an extent of Chinese medicinal materials in Niuhuangshangqing prescription and a dispersion medium with a weight ratio of 1:(1-2), wherein, the dispersion medium is vegetable oil. The soft capsule is prepared by extracting effective components from Chinese medicinal materials in Niuhuangshangqing prescription in accordance with the properties of the effective components by using different modern extraction techniques and making into soft capsule. The soft capsule has embedding and masking effects, and can prevent volatilization loss of oil components and oxygenation or photodecomposition of effective components. The soft capsule also has the advantages of rapid disintegration, uniform dispersion, high bioavailability, good stability of effective components, low liability of moisture absorption, good air tightness, direct intestinal absorption after disintegration, masking of unpleasant odors of effective components, convenience for administration and carrying, and so on.
Owner:TAIJI GROUP

Kit for detecting anti-psychosis drugs in serum and plasma by liquid chromatography tandem mass spectrometry method and application thereof

The invention provides a kit for detecting anti-psychosis drugs in a serum and plasma by a liquid chromatography tandem mass spectrometry method. The kit comprises drug standards: amsulpiride, aripiprazole, dehydroaripiprazole, chlorpromazine, clozapine, n-desmethylclozapine, risperidone, 9-hydroxyrisperidone, quetiapine, olanzapine, ziprasidone; drug internal standard compounds: amplepiride-d5, aripiprazole-d8, chlorpromazine-d3, clozapine-d8, risperidone-d4, 9-hydroxyrisperidone-d4, quetiapine-d8, olanzapine-d8, ziprasidone-d8; drug extraction compounds: methanol solution 60% (volume ratio),acetonitrile solution 20%, isopropanol solution 10%, purified water 10%; negative plasma; and a diluent: 50% aqueous methanol solution. The kit can be used to simultaneously detect anti-psychosis drugs and active metabolites thereof, the detection time is short and the flux is large.
Owner:HANGZHOU BAICHEN MEDICAL INSTR CO LTD +1

Method for extraction of paclitaxel from taxus chinensis

InactiveCN102838568ASolve the technical problems existing in the clinical application of medicineAvoid the disadvantages of difficult industrial production such as strict operating conditionsOrganic chemistryChemical treatmentChloroform methanol
Belonging to the technical field of medicine extraction, the invention discloses a method for extraction of paclitaxel from taxus chinensis. The extraction method provided in the invention consists of: using a methanol solution to conduct warm soaking extraction of taxus chinensis bark or branch and leaf powder, then carrying out chloroform extraction, performing silica gel column chromatography twice, implementing elution with a chloroform-methanol gradient solution and an n-hexane-acetic acid gradient elution respectively, and removing polar impurities so as to obtain a paclitaxel crude product; and further, carrying out third normal phase column chromatography, taking chemically treated silica gel as a stationary phase to effectively separate paclitaxel, recrystallizing the paclitaxel obtained from the column chromatography, thus obtaining a paclitaxel pure product with purity of over 98% pure product, with a process transfer rate being more than 80%. All the reagents used in the extraction method belong to the industrial grade, and the method provided in the invention has the advantages of wide applicability, strong innovation, simple process, low separation cost, high product yield, thus having innovative production value for industrial separation and production of paclitaxel.
Owner:JILIN PAIGAO BIOLOGICAL PHARMA

Chinese medicinal preparation for nourishing heart and tranquilizing mind and preparation method thereof

The invention provides a Chinese medicinal preparation for nourishing heart and tranquilizing mind, which comprises 12 gouts of raw materials, such as great burdock achene root, astragalus, spine date seeds, Siberian solomonseal rhizome, prepared rehmannia root and the like. The preparation can be powder, tablets, pills, capsules and the like. The preparation method comprises the following steps: crushing the medicaments; filtering the medicament to obtain siftage; sterilizing the siftage to obtain medicinal raw powder; and preparing tablets, pills and capsules by the medicinal raw powder. The preparation method can also comprises the following steps: preparing water extract by the medicaments; preparing oral liquid by the water extract according to a conventional method; drying, crushing and sieving the water extract, sterilizing the siftage to obtain medicinal extract powder; and preparing electuary or capsules by the medicinal extract powder. The method can also comprises the following steps: crushing the medicaments; sieving the medicaments to obtain siftage; sterilizing the siftage; dissolving refined honey with water, and adding the honey into the medicinal powder to prepare honey pills. The preparation has good curative effects in treating diseases of insufficiency of heart and spleen, deficiency of liver-yin and kidney-yin, deficiency of yang and neuradynamia, mainly treats dizziness and tinnitus, headache and dizziness, exhaust and fatigue, insomnia and forgettery, burnout and intake deficiency, depression, anxiety, palpitation, short of breath, night sweat and the like. The preparation is prepared by adopting pure Chinese medicaments, has the advantages of convenient use, safety and reliability and no toxic or side effect, and can be used for long time.
Owner:袁尚礼 +1

Highly effective abstraction method for preparation of high-purity ginko flavonoid

The present invention is high efficiency extracting process of high purity gingko flavone compound, and belongs to the field of natural plant medicine extracting technology. The extracting process includes the following steps: collecting green gingko leaf in autumn and stoving, crushing, extracting with 50-90 % concentration alcohol solution, concentrating the extracted solution to recover alcohol, diluting the concentrate and cooling to precipitate, adsorbing the supernatant with macroporous resin, desorbing with alcohol, vacuum concentrating the eluted solution, vacuum drying, crushing and packing. The process has no harmful matter residue, simple control and high extracting rate, and product has high effective component content and stable quality.
Owner:颜廷和

Effective part of seesile stemona alkaloid and its application

The present invention relates to extraction process and medicinal application of sessile stemona alkaloid. Sessile stemona alkaloid is extracted through the following steps: 1. extracting with alcohol solution or acid aqua; and 2. purifying with cation exchange resin. The sessile stemona alkaloid product has the sessile stemona alkaloid content over 50 %. The extracting process uses alcohol, no toxic organic solvent and reusable cation exchange resin, and has high safety and low cost. The medicine composition with the sessile stemona alkaloid may be used in treating skin diseases and diseases of respiratory tract, and in preventing and controlling plant diseases and pests.
Owner:SHANGHAI UNIV OF T C M

Auto-decocting device for plaster

The invention provides an auto-decocting device for plaster, and relates to the technical field of Chinese medicinal decoction equipment. The device comprises a machine frame, a control cabinet, a drug extraction system and a plaster refining system, wherein the drug extraction system and the plaster refining system are mounted on the machine frame, and the drug extraction system is installed at aposition higher than the plaster refining system; The first cylinder in the drug extraction system is connected with the second cylinder in the plaster refining system through a connecting line, anda first valve switch is installed on the connecting line, and the first cylinder and the bottom of the second cylinder are respectively provided with a heater. In addition, the device also has a medicine oil recovery system and a smoke purification system, realizes the automation of the plaster and the small batch decoction, has the advantages of excellent extraction of traditional Chinese medicine ingredients, high automation degree, low cost, environmental protection and no pollution, and can be widely used in the research and development institutions of traditional Chinese medicine, medicalinstitutions, and traditional Chinese medicine shops for the formulation and decoction of the plaster.
Owner:山东铎文医疗科技有限公司

Kit for detecting anti-depressant drugs in serum and plasma by liquid chromatography tandem mass spectrometry and application thereof

The invention provides a kit for detecting anti-depressant drugs in serum and plasma by liquid chromatography tandem mass spectrometry. The kit comprises drug standard substances, drug internal standardization compounds, drug extraction compositions, negative plasma and a diluent. The drug standard substances comprise amfebutamone, oxybupropion, citalopram, Escitalopram, venlafaxine, O-desmethylvenlafaxine, duloxetine, fluoxetine, norfloxetine, fluvoxamine, mirtazapine, paroxetine, sertraline and trazodone. The drug internal standardization compounds comprise amfebutamone-d9, oxybupropion-d6,citalopram-d6, venlafaxine-d6, O-desmethylvenlafaxine-d6, duloxetine-d3, fluoxetine-d6, norfloxetine-d6, fluvoxamine-d4, mirtazapine-d3, paroxetine-d6, sertraline-d3 and trazodone-d6. The drug extraction compositions comprise, by volume, 60% of methanol solution, 20% of acetonitrile solution, 10% of isopropyl alcohol solution and 10% of purified water. The diluent comprises 50 % of methanol waterfluid. The kit can be used for simultaneous detection of the anti-depressant drugs and active metabolites, the detection time is short, and flux is high.
Owner:HANGZHOU BAICHEN MEDICAL INSTR CO LTD +1

Centrifugal device for extracting drug ingredients and method thereof

The invention provides a centrifugal device for extracting drug ingredients and a method thereof. The centrifugal device for extracting the drug ingredients comprises a cylinder body, a base, a centrifugal extraction basket, a rotary driving device and a control part, wherein the cylinder body is used for containing drug extraction solvent and is fixed on the base; the centrifugal extraction basket is supported and arranged in the cylinder body by a transmission shaft connected with the centrifugal extraction basket, and is connected with the rotary driving device by the transmission shaft and other transmission mechanisms; by applying rotary driving force to the centrifugal extraction basket, the rotary driving device enables the centrifugal extraction basket to rotate by the transmission shaft and other transmission mechanisms, animals and plants can be arranged in the centrifugal extraction basket, and the drug extraction solvent in the cylinder body flows into the periphery wall of the extraction basket through a plurality of through holes arranged on the periphery wall of the centrifugal extraction basket; according to an externally inputted running instruction, the control part controls the soak time and the rotational speed and the rotation time of an electromotor so that the centrifugal device for extracting the drug ingredients can sequentially carry out the working procedures of soaking, centrifugal extraction and centrifugal liquid removal; and by enabling the centrifugal extraction basket to rotate at a high speed, the working procedure of centrifugal liquid removal enables the centrifugal extraction basket to generate the centrifugal force on the animals and the plants so that liquid removal can be carried out on the animals and the plants.
Owner:BEIJING COLLAB PHARMA +1

On-line ultraviolet analysis method for dynamic tendency during extraction process of traditional Chinese medicines

ActiveCN104122221AEnsure safetyImprove the level of online quality controlColor/spectral properties measurementsNon destructiveUltraviolet
The invention discloses an on-line ultraviolet analysis method for the dynamic tendency during extraction process of traditional Chinese medicines. The method comprises the steps of sampling in real time, detecting an ultraviolet reference spectrum and an extracting solution spectrum, obtaining the absorbancy, carrying out spectroscopy data pretreatment, calculating the absorbancy gradient, and the like; the method can be used for analyzing the dynamic tendency during the extraction process of the Chinese traditional medicines by analyzing the change situation of the absorbancy. According to the method, later off-line ultraviolet and the contents of solids are detected, so that the progress of the extraction process of the traditional Chinese medicines can be accurately reflected, the on-line quality control level during the process can be improved, quality information during the extraction can be quickly obtained in a non-destructive and real-time manner, the abnormal operation can be timely found and corrected, and the traditional Chinese medicines are safe, stable and effective.
Owner:BEIJING KANGRENTANG PHARMA +1

Hydroxy-beta-sanshool monomer preparation method

The invention provides a hydroxy-beta-sanshool monomer preparation method and belongs to the technical field of natural drug extraction. The preparation method effectively realizes extraction of a high-concentration hydroxy-beta-sanshool monomer from a Chinese prickly ash raw material. The preparation method comprises 1, extracting a hydroxysanshool mixture, 2, carrying out enrichment and pressure reduction condensation on the hydroxysanshool mixture to obtain hydroxysanshool mixture extract, 3, transforming hydroxy-beta-sanshool to improve hydroxy-beta-sanshool content of the hydroxysanshool mixture extract solution, 4, purifying the hydroxy-beta-sanshool to obtain a hydroxy-beta-sanshool monomer with purity of 70% or more, and 5, carrying out recrystallization to obtain a hydroxy-beta-sanshool monomer with purity of 98% or more. The preparation method is mainly used for preparing the hydroxy-beta-sanshool monomer.
Owner:SOUTHWEST JIAOTONG UNIV

Extraction process of paeoniflorin

The invention provides an extraction process of paeoniflorin, which relates to the field of drug extraction and solves the problems of low production efficiency, poor product purity and inapplicability of industrial production and large-scale production in the prior art. The extraction process of paeoniflorin adopts the combination of an enzymatic method and a non-alcoholic liquid phase extraction process and comprises the following steps: firstly adding enzyme into Chinese herbal medicines containing paeoniflorin active ingredients to carry out enzymolysis, adding appropriate amount of water to decoct the Chinese herbal medicines after enzymolysis and standing the Chinese herbal medicines for cooling; centrifugally separating extract at high speed, collecting and filtering supernatant liquid, collecting and concentrating filtrate, eluting condensate for decolourization on macroporous adsorption resin columns to prepare crude paeoniflorin products and refining the crude paeoniflorin products to obtain the paeoniflorin with purity of more than 98 percent. Because of adopting the enzymatic method, the extraction process of the paeoniflorin enables the active ingredients in the raw materials to be extracted sufficiently and easily. Because of adopting the non-alcoholic liquid phase extraction process, the whole extraction process of the paeoniflorin has the obvious advantages of high product purity, high yield, low costs of construction and production, simple and convenient operation, and the like.
Owner:张守力

Medicament for treating senile dementia and preparation method thereof

The invention discloses a medicament for treating senile dementia and a preparation method thereof. The medicament consists of active ingredients or pharmaceutically acceptable carriers. The medicament is prepared from the following active ingredients in part by weight: 1 to 15 parts of pinellia tuber, 1 to 15 parts of bamboo shavings, 1 to 15 parts of immature bitter orange, 1 to 15 parts of grassleaf sweelflag rhizome, 1 to 15 parts of thinleaf milkwort root-bark, 1 to 10 parts of ginseng, 1 to 15 parts of ligusticum wallichii and 1 to 20 parts of prepared rehmannia rhizome. The medicament is also prepared from one or more raw materials in part by weight: 1 to 15 parts of Japanese ginseng, 1 to 15 parts of tuckahoe, 1 to 15 parts of dried orange peel, 1 to 10 parts of white mustard seed, 1 to 10 parts of leech and 1 to 20 parts of prepared multiflower knotweed tuber. The medicament can be prepared into formulations such as powder, tablets, capsules, dispersible tablets, pellets, injection, oral liquid and granules. The preparation method comprises the following steps of: chopping raw materials into small pieces or crushing the raw materials into coarse powder, mixing extracts of the raw materials, which are obtained by using water or ethanol, or continuing concentrating to form dry extractum, or mixing the mixture of the extracts and the carriers. Clinical application proves that the medicament is an effective medicament for treating alzheimer's diseases and improving the memory, cognitive disorder and living abilities of patients.
Owner:HUBEI UNIV OF CHINESE MEDICINE

Kit for determining antianxiety/hypnotic type drugs in serum and plasma through liquid chromatography tandem mass spectrometry and application thereof

The invention provides a kit for determining antianxiety / hypnotic type drugs in serum and plasma through liquid chromatography tandem mass spectrometry. The kit comprises the following constituents: drug standards comprising bromazepam, clonazepam, diazepam, lorazepam, midazolam, nitrazepam, oxazepam and Temazepam; drug internal standard compounds comprising alprazolam-d5, clonazepam-d4, diazepam-d5, lorazepam-d4, midazolam-d4, nitrazepam-d5, oxazepam-d5 and Temazepam-d5; drug extraction compositions comprising, by volume, 60% of methanol solution, 20% of acetonitrile solution, 10% of isopropanol solution and 10% of purified water; negative plasma; and diluent: 50% of carbinol water solution. The kit can be used for simultaneously determining antianxiety / hypnotic type drugs and active metabolites thereof, and has the advantages of short determination time and high flux.
Owner:HANGZHOU BAICHEN MEDICAL INSTR CO LTD +1

Method for Producing a Drug Extract That Contains Hydroxystilbene

The invention relates to a method for producing drug extracts that contain hydroxystilbene from a vegetable drug and to the use of various agents for pharmaceutical and non-pharmaceutical purposes.
Owner:HEGER PETER

Compound traditional Chinese medicine extract for preventing poultry coccidiosis and application of extract

ActiveCN103860715ASolve the problem of chemical resistanceSolve the disease problemAntiparasitic agentsPlant ingredientsCelluloseCoccidiosis
The invention relates to the technical field of compound traditional Chinese medicines for animals and particularly discloses a compound traditional Chinese medicine extract for preventing poultry coccidiosis, a preparation method and an application of the extract. The compound traditional Chinese medicine extract is prepared from six medicines such as antifebrile dichroa, sweet wormwood, hairyvein agrimony, golden cypress, Chinese pulsatilla root and radix sophorae flavescentis according to certain matching ratio and certain process. The compound traditional Chinese medicine is applicable to prevention and treatment of the poultry coccidiosis and effectively avoids medicine residue and medicine resistance caused by antibiotics; according to the physiological characteristics of the poultry, especially the characteristic of short genital tract of the poultry, for the problem of difficult digestion and absorption of cellulose of the traditional Chinese medicine, the medicines are made into the traditional Chinese medicine extract which can be taken by drinking water, so that the convenient effect and the convenience in absorption are achieved, the purpose of rapid treatment can be achieved, and the economic benefit and the social benefit are good.
Owner:湖北欣华生态畜禽开发有限公司

Medicine extraction device and technique thereof

The invention discloses a medicine extraction device. The liquid outlet of a first extraction tank is communicated with the liquid inlet of a first concentrator; and a concentrate outlet of the first concentrator is communicated with a concentrate inlet of an alcohol precipitation tank. The medicine extraction device is characterized in that in a liquid collector of the first concentrator, the position of the outlet of a liquid outlet pipe is lower than and far away from the position of a vacuum pipe in the liquid collector; condensate, flowing outlet from the liquid outlet pipe, directly flows in a liquid accommodating cavity at the bottom of the liquid collector, and then flows in a liquid reception tank for preservation to avoid or reduce the material leakage problem due to leadout of the condensate by a vacuum system; and at the same time, the collected condensate can be directly discharged through a water drainage pump without implementing the device evacuation and the secondary vacuum pumping, so that the operation is easy, the energy consumption is reduced, and the medicine extraction efficiency of the medicine extraction device is improved. Meanwhile, the invention further discloses a technique for extracting medicines by using the device; and the technique is suitable for extracting natural medicines.
Owner:HUNAN NUOZ BIOLOGICAL TECH CO LTD

Aplotaxis carminative sustained-release preparation and preparation method thereof

The invention relates to an aplotaxis carminative sustained-release preparation and a preparation method thereof. The preparation method comprises the following steps: according to the traditional proportion, preparing aplotaxis, amomum fruit, vinegared rhizoma cyperi, Areca catechu, licorice root, dried orange peel, Mangnolia officinalis, stir-fried fructus aurantii, stir-fried rhizoma atractylodis, stir-fried green tangerine orange peel and ginger into an aplotaxis carminative medicine extract; and preparing 5-50 parts of aplotaxis carminative medicine extract, 10-200 parts of filler, 10-100 parts of sustained-release material, 0-30 parts of disintegrant, 0-10 parts of lubricant, 0-10 parts of flow aid and 10-200 parts of hot-melt extrusion auxiliary material into the aplotaxis carminative sustained-release preparation by using a conventional preparation technique or hot-melt extrusion preparation technique. The aplotaxis carminative sustained-release preparation provided by the invention has the advantages of unique technique, high stability and stable and long-lasting preparation release, and can be continuously and stably released in vivo for 12 hours, so that the active pharmaceutical ingredients can last in vivo for a long time and can be absorbed continuously by human bodies, thereby achieving the goal of long-acting.
Owner:山西振东五和堂制药有限公司

Pharmaceutical composition for treating spleen deficiency and preparation method thereof

The invention provides a pharmaceutical composition for treating spleen deficiency and a preparation method thereof. Based on parts by weight, the preparation method of the pharmaceutical composition comprises the following steps of: mixing 3-5 parts of ginseng, 3-5 parts of dangshen, 5-10 parts of astragalus membranaceus and 15-25 parts of angelica, and adding ethanol for extracting; mixing 15-25 parts of radix paeoniae alba, 8-13 parts of pericarpium citri reticulatae, 8-13 parts of elecampane, 8-13 parts of yam, 8-13 parts of hyacinth bean, 8-13 parts of licorice, 15-25 parts of ligusticum wallichii, 5-10 parts of cinnamon, 1-3 parts of rattletop, 1-3 parts of radix bupleuri, 1-3 parts of fructus alpiniae oxyphyllae, 1-3 parts of Sichuan pepper,1-3 parts of monkshood, 1-3 parts of rhizoma zingiberis and 10-15 parts of dogwood, and adding pure water for extracting; mixing 15-25 parts of poria cocos, 15-25 parts of bighead atractylodes rhizome and 5-10 parts of cassia twig, adding cellulose, extracting through water, inactivating the extracting solution for later use, mixing the extracting solutions, carrying out vacuum freeze drying to obtain solid dry paste of a drug extract, and carrying out superfine grinding and pelletizing to prepare the necessary pharmaceutical composition. The pharmaceutical composition provided by the invention is scientific in formula, suitable for mass production, free of untoward effect, strong in potency, quick to become effective and convenient to take.
Owner:ZHEJIANG IND & TRADE VACATIONAL COLLEGE

Preparation method of radix salviae miltiorrhizae extracting solution by taking tanshinol as target object

The invention relates to a preparation method of a radix salviae miltiorrhizae extracting solution by taking tanshinol as a target object, and belongs to the technical field of medicine extraction methods. The method comprises the following steps of processing by using a water extracting lime-sulphur method, as well as alcohol precipitation and water precipitation processing, removing macromolecular substances, such as a large number of protein and tannin, in an extracting solution, and then performing hydrolysis at proper temperature under the alkaline condition, so as to obtain a radix salviae miltiorrhizae extract which contains high concentration of the tanshinol, for preparing injection or medicines of other preparation forms containing the tanshinol. The preparation method provided by the invention has the advantages that the conversion ratio from salvianolic acids to the tanshinol is greatly improved, the target object taking the tanshinol as a main ingredient in the extract is realized, the extraction process is simple and easy to operate, the dosage of organic solvent is less, and the equipment requirements are simple; meanwhile, the macromolecular substances, such as the large number of protein and the tannin, in the extracting solution are removed, the prepared radix salviae miltiorrhizae extract is high in tanshinol content, is easy to store, the tanshinol content in the storage process is stable, and an effective raw material for preparing tanshinol preparations is provided.
Owner:吉林四长制药有限公司

Method for increasing purity of extracted hesperidin and hesperidin

InactiveCN108299520AHigh purityDoes not affect extraction efficiencySugar derivativesSugar derivatives preparationFiltrationAurantii fructus immaturus
The invention relates to the field of drug extraction, in particular to a method for increasing the purity of extracted hesperidin and the hesperidin. The method for increasing the purity of the extracted hesperidin includes the following steps that an alkaline substance is adopted to adjust the pH value of aurantii fructus immaturus coarse powder to 8-9, then, the aurantii fructus immaturus coarse powder is soaked for 1-2 hours, then, filtration is carried out to remove mother liquor, and residues obtained through filtration are extracted to obtain the hesperidin. According to the method forincreasing the purity of the extracted hesperidin, by adding the alkaline substance into the aurantii fructus immaturus coarse powder, impurities in aurantii fructus immaturus extract can be largely removed, the purity of the hesperidin is increased, but the extraction efficiency of the hesperidin cannot be influenced. The method for increasing the purity of the extracted hesperidin can be appliedto industrial production in a large scale.
Owner:SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES

Immunosuppressant drug extraction reagent for immunoassays

An improved extractive reagent composition and method for extracting an immunosuppressant drug, such as sirolimus, tacrolimus or cyclosporine, from blood samples while yielding a test sample extract that has low vapor pressure and is compatible with immunoassay components. The inventive reagent composition comprises dimethyl sulfoxide (DMSO), at least one divalent metal salt and water. The sample extracts resulting from use of each of these combinations have low vapor pressure and are compatible with immunochemistry assays.
Owner:ABBOTT LAB INC

A thermal energy utilization device for protein drug extraction

The invention provides a heat energy utilization device for protein drug extraction, which comprises a shell cover fixed on the outer side of the outer shell by bolts, and rubber gaskets are fixed on the inner side of the outer shell and the shell cover by bonding; the inner bottom of the outer shell Both ends are integrated with four sets of column structures; the outer shell and the shell cover are clamped with rubber gaskets and columns to install an inner tank; the back of the shell cover is fixed with a suction valve through screw connection, There is an outer shell and a shell cover, which provides a vacuum installation environment for the inner tank, which greatly improves the heat preservation function of the inner tank, and at the same time provides a convenient installation and replacement function for the inner tank, which is convenient for assembly. The inclined plate structure can straighten out the water flow and ensure that the water is evenly stirred when it is subjected to thermal expansion and contraction.
Owner:山西康必健医疗科技股份有限公司

Natural drug extract and its preparation method

The invention relates to a natural drug extract and its preparation method. The natural drug extract is composed of an astragalus Alpinia katsumadai decocted concentrated extract, astragalus polysaccharides and an Alpinia katsumadai ethyl acetate extract in a ratio of 2-8:3-9:2-3. The composition provided in the invention has excellent efficacy on cancer chemotherapy related diarrhea and simultaneously has a synergistic effect on cancer chemotherapy.
Owner:石强

Drug extraction instrument cleaning device

The invention discloses a drug extraction instrument cleaning device. The drug extraction instrument cleaning device comprises a shell, supporting legs, a cleaning box and a purification chamber. Thesupporting legs are arranged at the bottom of the shell. The cleaning box is fixedly arranged in the shell. A cleaning tank is fixedly arranged in the cleaning box. Ultrasonic generators are uniformlyand fixedly mounted on the outer surface of the cleaning tank and are electrically connected with a controller fixedly arranged on the outer surface of the shell through wires. A stirring shaft is fixedly arranged in the cleaning tank. One end of the stirring shaft penetrates through the bottom of the cleaning tank and is connected with a rotary motor rotary shaft fixedly arranged at the bottom of the cleaning box. The surface of the stirring shaft is fixedly provided with cleaning brushes. A water pipe is fixedly connected to the bottom of the cleaning box. The purification chamber comprisesa disinfection box and a filter. The cleaning box is connected with the disinfection box in the purification chamber through the water pipe. The drug extraction instrument cleaning device is high incleaning efficiency, cleaned sewage is discharged after being purified, and pollution to the environment is reduced.
Owner:王变芝

Washing-free bath dew capable of curing cold and preparation method thereof

The invention discloses washing-free bath dew capable of curing cold and a preparation method thereof, wherein the bath dew is prepared by medicine extracts, such as anionic surfactant, ampholytic surfactant, kudzu root, fructus viticis, etc, humectant and preservative. The bath dew cures cold through active ingredients of pure Chinese herbal preparations; effective ingredients of medicine are adhered to the surface of the skin for a long time in a form of washing-free bath dew; the effective ingredients of Chinese herbal medicine volatilize slowly and has effects for preventing and curing cold in a longer time; the bath dew can moisten and moisturize skin so as to overcome side effect on human caused by chemical agents.
Owner:董根荣
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