Novel mangiferin calcium salts, the method for its preparation and its use
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- CHANGZHOU DEZE MEDICAL SCI CO LTD
- Publication Date
- 2010-09-29
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
technical field
[0001] The invention relates to a mangiferin calcium salt, a preparation method thereof and an application as an insulin sensitizer for treating diabetes and its complications. Background technique
[0002] Insulin resistance (IR) refers to a series of pathological and clinical manifestations caused by the decrease or loss of the responsiveness of the target organs and tissues of insulin to the biological effects of insulin. A large number of studies have shown that IR runs through the development of type 2 diabetes and is a prominent feature of type 2 diabetes. With IR at its core, it can lead to hyperglycemia, hypertension, microalbuminuria, inflammation, hyperfibrinolytic state, abnormal lipid metabolism, endothelial dysfunction, atherosclerosis, and cardiovascular disease. Therefore, by enhancing the action of insulin and improving the sensitivity of insulin receptors, develop insulin sensitizers to treat diabetes and its complications (diabetic complica...