Ir-Gd metal complex fluorescent nanoparticle and preparation method and application thereof

Abstract

The invention relates to the field of materials and magnetic imaging contrast agents, and discloses an Ir-Gd metal complex fluorescent nanoparticle, which has average diameter of 50-60nm, and a structural formula shown as a formula (I), wherein n = 1-3. The particle has stronger relaxation capacity and phosphorescent light emission property, can be used for preparing magnetic resonance imaging contrast agents and realizing dual functions. The invention also provides a method for preparing the nanoparticle, and the method has simple operation, mild reaction and no pollution.

Description

technical field The invention relates to the fields of materials and magnetic imaging contrast agents, in particular to a novel Ir-Gd metal complex fluorescent nanoparticle with simple preparation, which can be used for multifunctional magnetic imaging. Background technique Lanthanide metals are famous for their narrow emission peaks and high quantum efficiency, but their excitation wavelengths are in the near-infrared region, so how to excite lanthanide metals has become a hot research topic in recent years. A few years ago, a new type of d-f metal compound was synthesized. It transfers the energy of the triplet excited state of the transition metal to the benzene derivative to emit near-infrared light, thereby exciting the lanthanide metal to emit light. The 4f layer electron orbital of lanthanide rare earth ions is not full of electrons, while the 5s and 5p layer orbitals are full of electrons, so the 4f layer electrons are shielded by the outer 5s and 5p layer electron...

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Problems solved by technology

However, as a magnetic functional material with superior performance, the value of gadolinium in d-f metal complexes has not been fully developed

So far, there have been no reports on the use of d-f iridium complexes to excite gadolinium for magnetic functional materials

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