Ginkgolides K and compound thereof as well as preparation method and use thereof
A technology of ginkgolides and complexes, which is applied in the field of ginkgolides and their complexes, to achieve the effect of reducing the degree of nuclear dissolution and softening focus
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0085] Example 1. A preparation method of ginkgolide K, the steps of which are as follows: add ginkgolide B to an alkaline aqueous solution, heat and dissolve in a water bath, and keep warm; after testing that the ginkgolide B is basically completely transformed, then adjust the pH value with an acidic aqueous solution Until the solution becomes acidic, let it stand still, filter to obtain a precipitate, take the precipitate and wash it with water, then dissolve it with an organic solvent, concentrate, and recrystallize until the purity reaches more than 90%.
Embodiment 2
[0086] Example 2. A preparation method of ginkgolide K, the steps of which are as follows: add ginkgolide extract containing ginkgolide B to a mixed solution of alkaline water and alcohol, heat and dissolve in a water bath, and keep warm; after testing, ginkgolide B is basically After the transformation is complete, adjust the pH value with an acidic aqueous solution until the solution is acidic, let it stand still, and centrifuge to obtain a precipitate. The precipitate is washed with water, dissolved in an organic solvent, concentrated, and recrystallized until the purity reaches more than 90%.
Embodiment 3
[0087] Example 3. A preparation method of ginkgolide K, the steps of which are as follows: add ginkgolide B to a water-alcohol mixed solution, heat and dissolve in a water bath, and keep warm; after testing that the ginkgolide B has basically transformed completely, concentrate and crystallize, and obtain The crystals are then dissolved in an organic solvent, concentrated, and recrystallized until the purity reaches more than 90%.
PUM
Property | Measurement | Unit |
---|---|---|
particle diameter | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com