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Application of yeast dextran injection for improving immune efficiency of foot-and-mouth disease vaccine of dairy cow

A technology of yeast glucan and injection, which is applied in the direction of medical preparations containing active ingredients, drug delivery, organic active ingredients, etc. It can solve the problems of immune effect impact and small immune stimulation of cells, so as to enhance immune efficacy, Enhanced stimulating effect, good safety effect

Inactive Publication Date: 2012-05-30
天津市农业科学院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this vaccine is an inactivated vaccine, which can only stimulate the body to produce humoral immunity, and has little stimulating effect on cellular immunity, and its immune effect is affected to a certain extent.

Method used

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  • Application of yeast dextran injection for improving immune efficiency of foot-and-mouth disease vaccine of dairy cow
  • Application of yeast dextran injection for improving immune efficiency of foot-and-mouth disease vaccine of dairy cow
  • Application of yeast dextran injection for improving immune efficiency of foot-and-mouth disease vaccine of dairy cow

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Carboxymethyl yeast dextran 2g, sterilized, dissolved in 98ml of distilled water for injection, sub-packed and sealed is the injection.

Embodiment 2

[0065] Carboxymethyl yeast dextran 3g, sterilized, dissolved in 97ml of distilled water for injection, subpackaged and sealed to form injection.

Embodiment 3

[0067] Carboxymethyl yeast dextran 4g, sterilized, dissolved in 96ml of distilled water for injection, sub-packed and sealed is the injection.

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PUM

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Abstract

The invention discloses an application of a yeast dextran injection for improving the immune efficiency of a foot-and-mouth disease vaccine of a dairy cow. Simultaneously, the invention also discloses an application of the yeast dextran injection for enhancing the cellular immune function of the dairy cow, wherein the yeast dextran injection is a 2%-6% carboxymethyl yeast dextran water solution. The yeast dextran injection prepared by the invention is safe, does not have adverse reaction, can effectively enhance the cellular immune function of the dairy cow organism and improve the antibody level of the dairy cow inoculated with an foot-and-mouth disease inactivated vaccine, and can enhance the disease resistance of animals.

Description

technical field [0001] The invention belongs to the technical field of veterinary pharmaceutical preparations, and relates to the application of water-soluble yeast glucan in livestock and poultry, more specifically, the application of yeast glucan injection in improving the immune efficacy of milk cow foot-and-mouth disease vaccine. technical background [0002] Yeast glucan is a pure natural active immune regulator extracted and refined from yeast, which can effectively activate macrophages and induce a series of immune responses in the body, thereby improving the body's immune function. In addition, dextran has the functions of scavenging free radicals, anti-radiation, anti-tumor, dissolving cholesterol, preventing hyperlipidemia and infection caused by viruses, fungi, bacteria, etc., so it is widely used in medicine, food, cosmetics, feed and other industries. [0003] Yeast glucan extracted from yeast cell wall is insoluble in water. Adding water-insoluble yeast glucan ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/08A61K31/716A61P37/04
Inventor 鄢明华孙英峰王英珍王东池晶晶张健李秀丽任卫科王建国张莉韩伟王成龙
Owner 天津市农业科学院
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