Sodium alga acid composition and application thereof

Abstract

The invention relates to application of a hemostasis material of sodium alga acid and sodium alga acid added calcium salt or zinc salt composition in wound surface hemostasis. The sodium alga acid composition comprises 50-100 parts by weight of sodium alga acid and 0.5-50 parts by weight of calcium salt. The invention also provides a hemostasis material prepared from the sodium alga acid composition and at least one pharmaceutically acceptable solvent, carrier and / or excipient. The sodium alga acid composition and the hemostasis material in the invention have the characteristics of rapid hemostasis, good biocompatibility, biodegradation absorbability, simpleness in treatment, no need of debridement, low cost and the like, and is suitable for the hemostasis in the wound surface, especially in war wound surface.

Description

Technical field:

[0001] The invention relates to a new application of sodium alginate directly as a hemostatic material, a sodium alginate composition added with calcium salt and / or zinc salt, a hemostatic material containing the sodium alginate composition and their application in wound surface hemostasis. Background technique:

[0002] The treatment of war wounds focuses on early treatment at the front of the battlefield and on the way to evacuation, prolonging the "golden hour" treatment time limit, and reducing the rate of blood loss and casualties. At present, the main treatment measures for war wounds are physical compression hemostasis (such as gauze, tourniquet, etc.), but the disadvantage of compression hemostasis is that if the tourniquet is too tight, it will easily cause tissue ischemia and necrosis, and excessive force may cause rib fractures; Moreover, when bleeding occurs in a traumatized patient with important organ injury (heart, brain, lung, liver, spleen, ...

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