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Preparation method of granules for treating nephrolith

The technology of kidney stone pass and granule is applied in the field of preparation of traditional Chinese medicine preparations, which can solve the problems of increasing the dosage of raw materials, increasing production costs, low yield of extracts, etc., and achieves shortening production time, saving energy consumption, and reducing production costs. Effect

Active Publication Date: 2012-12-26
JIANGSU SUNAN PHARMA IND CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The dosage forms of medicines for treating kidney stones are basically tablets or capsules, and its functions are to clear away heat and dampness, promote blood circulation and relieve pain, fossilize and expel stones; but there is no report of granules at present
In the process of preparing tablets or capsules, the yield of the extract is low, generally around 60%. If the yield of the extract is increased, the consumption of raw materials will inevitably be increased, thereby increasing the production cost

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Embodiment 1: A preparation method of Shenshitong granules, the method is:

[0016] The first step is to pre-treat each API; the specific method is: remove the impurities of Lysimachia serrata, slightly wash, cut into sections, and dry; remove the impurities from the sage, wash, cut into sections, and dry; remove the woody incense from impurities, Soak, moisten thoroughly, cut into thick slices, and dry; remove impurities, wash, slightly moisturize, cut into sections, and dry the dianthus; remove impurities, wash, moisturize, remove reed, cut into sections, and dry; Remove impurities and remaining stems of Salvia, wash, moisten thoroughly, cut into thick slices, and dry; bag, weigh, label, and put the dried medicinal materials into the clean medicinal material warehouse;

[0017] The second step is the extraction process; weigh the pure medicinal materials according to the following prescription, and count them in parts by weight: 100 parts of Lysimachia, 60 parts of Lysimac...

Embodiment 2

[0020] Example 2: Basically the same as Example 1, but the difference is the prescription, in parts by weight: 90 parts of Lysimachia japonicus, 30 parts of yusuke, 50 parts of sea sand, 20 parts of broiled chicken, 15 parts of achyranthes, Stir-fried King Buliu line 110 parts, dianthus 40 parts, salvia miltiorrhiza 30 parts, vinegar Corydalis 20 parts, wood incense 30 parts; the yield of the extract in the preparation process is 90%.

Embodiment 3

[0021] Example 3: Basically the same as Example 1, the difference is the prescription, in parts by weight: 95 parts of Lysimachia, 50 parts of Lysimachia, 45 parts of Haijinsha, 60 parts of Hot Gallus gallus, 25 parts of Achyranthes, 70 parts of Fried King Buliu, 30 parts of dianthus, 50 parts of Salvia miltiorrhiza, 40 parts of Corydalis made from vinegar, and 10 parts of Muxiang; the yield of the extract during the preparation process was 88%.

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PUM

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Abstract

The invention discloses a preparation method of granules for treating nephrolith, which comprises the following steps of: putting climbing fern spore and fried cowherb seed into a cloth bag; then, putting the cloth bag together with lysimachia, polygonum aviculare, baked gizzard pepsin, achyranthes, fringed pink, red sage root, vinegar prepared corydalis tuber and costus root into an extracting tank; adding water for decocting twice; mixing the decoctions; filtering; concentrating the filtered solution to obtain extract for treating nephrolith; mixing sucrose and dextrin in a trough type mixing machine; adding the extract for treating nephrolith; mixing for 15-20 minutes to obtain soft materials; then granulating; drying; and controlling the moisture within 2.0% to obtain the granules fortreating nephrolith. By adopting the invention, the extract yield can be increased by 20% under the condition that the same amount of raw medicines are used, thus the production cost can be greatly lowered; by adopting a double-effect concentrator for concentrating, the production time can be shortened; and moreover, no pollution is caused, the medicinal odor is thick, the cleaning operation is convenient, and the energy sources are saved.

Description

Technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine preparation, in particular to a preparation method of Shenshitong granules for treating kidney stones. Background technique [0002] Kidney stones refer to stones that occur in the renal calyx, renal pelvis, and the junction between the renal pelvis and the ureter. Most are located in the renal pelvis and calyces, and renal parenchymal stones are rare. Plain film shows that there are single or multiple round, oval or blunt triangular dense shadows in the kidney area, with high and uniform density. The edges are smooth, but some are not smooth and mulberry-like. The kidney is the main part of the urinary tract that forms stones. Stones in any other part can originate in the kidney. Almost all ureteral stones come from the kidney, and kidney stones are more likely to directly damage the kidneys than stones in any other part. Therefore, early diagnosis and treatment are very impo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K36/704A61P13/04A61K35/37A61K35/57
Inventor 俞洋
Owner JIANGSU SUNAN PHARMA IND CO LTD
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