Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method of patrimia scabiosaefolia extract

The technology of Huanghuabaijian and extract is applied in the field of preparation of preparations, and can solve the problems of incapable of qualitative and quantitative detection of products, incomplete extraction of volatile oils, and difficulty in guaranteeing the quality of medicines. rate increase effect

Active Publication Date: 2012-07-18
云南云河药业股份有限公司
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The applicant's first Paijiang Tablets with Huanghua Paijiang as the main ingredient was first included in the 1977 edition of "Chinese Pharmacopoeia", but limited to the conditions at that time, the prescription only pointed out under the preparation method of the Chinese Pharmacopoeia Using 60% ethanol as a solvent for percolation extraction, there is no clear process conditions such as immersion time, percolation speed and percolation liquid collection dose in the percolation process, so it cannot be used as a standard production process to guide the production of drugs, as an active ingredient The volatile oil is not all extracted
At the same time, in the "Pharmacopia Standards" of Paijiang Tablets produced, there are only three large categories of color reactions of plant ingredients that are not very specific, and the product cannot be qualitatively and quantitatively tested, making it difficult to guarantee the quality of the drug.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of patrimia scabiosaefolia extract
  • Preparation method of patrimia scabiosaefolia extract
  • Preparation method of patrimia scabiosaefolia extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Weigh 1000g of the raw material of Huanghua Paijiang, pass it through a 40-mesh sieve after purification, and pulverize it into a coarse powder for later use; use the steam distillation method, put the raw material coarse powder on the sieve plate of the distillation pot for distillation, and the resulting mixture steam along the The gooseneck on the top of the pot is introduced into the condenser and cooled to obtain a liquid mixture of water and volatile oil, which is separated to obtain the volatile oil of Huanghuapaijiang; dry the distilled raw material of Huanghuapaijiang (or use a concentration of 95% after measuring the water content) The ethanol is adjusted to have an ethanol content of 60%), and the ethanol with a concentration of 60% is used as a solvent to fully wet the above-mentioned raw material coarse powder and let it stand for 60 minutes; the wet raw material coarse powder is placed in a percolator, and the concentration is 60%, the ethanol solution whos...

Embodiment 2

[0023] Repeat Example 1 with the following differences: the concentration temperature is 60° C., and the steam heating pressure is 0.15 MPa.

Embodiment 3

[0025] Repeat Example 1 with the following differences: the concentration temperature is 50° C., and the steam heating pressure is 0.1 MPa.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a preparation method of a patrimia scabiosaefolia extract. The preparation method comprises the steps of: pulverizing cleaned patrimia scabiosaefolia raw materials into coarse powder; preparing a liquid mixture of water and volatile oil by adopting a stream distillation method; separating the liquid mixture to obtain patrimia scabiosaefolia volatile oil; drying the raw material coarse powder and immersing with an ethanol solution; adding an ethanol solution the weight of which is 15 times of the weight of the raw material coarse powder for percolation; collecting the percolate, decompressing and concentrating, and recovering ethanol; and adding the extracted volatile oil, and uniformly mixing to obtain the patrimia scabiosaefolia extract. The preparation method disclosed by the invention optimizes the percolation process, the yield of the obtained patrimia scabiosaefolia extract is increased greatly, and the content and the transfer rate of oleanolic acid are increased effectively and obviously. The patrimia scabiosaefolia extract has obvious effect on tranquilizing central nerves.

Description

technical field [0001] The invention relates to the technical field of drugs for treating central nervous system, in particular to a method for preparing a preparation for central nervous system sedation extracted from the crude drug of Patrinia officinalis. Background technique [0002] With the rapid development of social economy and the improvement of people's living standards, social competition is also intensifying. The severe employment situation and increasing work pressure. People are prone to enter the "sub-health" state under such tense environmental pressure for a long time. Among them, the most obvious manifestation is neurasthenia or mental illness with insomnia as the main symptom. According to statistics, the incidence of insomnia in the Chinese population is about 30%. [0003] At present, there are many kinds of central nervous system sedative drugs for the treatment of insomnia. Western medicines mainly focus on benzodiazepines such as diazepam, barbiturate...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61P25/20A61K125/00
Inventor 刘剑胡松谋
Owner 云南云河药业股份有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products