The invention relates to a traditional Chinese medicine composition for treating urinary system stones. The traditional Chinese medicine composition is prepared by longhairy antenoron herb, Japanese climbing fern spore, clematis root, cassia seed, chicken's gizzard-membrane, officinal magnolia bark, reed rhizome, Chinese thorowax root, giant knotweed rhizome, talc, bitter orange, virgate wormwood herb, rhubarb, pyrrosia leaf, cluster mallow fruit, medicinal cyathula root and/or a pharmaceutically acceptable carrier. The invention further relates to a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition has the efficacies of clearing heat, promoting diuresis, invigorating spleen and kidney, removing dampness, relieving masses, regulating qi, activating stagnancy, softening hardness, resolving stones, treating stranguria and expelling stones and is used for treating kidney stones, gall-stones, ureteral stones, bladder stones and the like.