Portable peritoneal dialysis system

Abstract

A portable peritoneal dialysis system for a patient includes an inlet port for providing inflow to the patient's peritoneal cavity, an outlet port for providing outflow from the patient's peritoneal cavity, and a volume of dialysate for flow into and out of the patient's peritoneal cavity, thereby removing from the dialysate uremic waste metabolites that have diffused into the dialysate. The portable peritoneal dialysis system also includes a closed liquid flow loop, including a pump, for flowing the dialysate into and out of the patient's peritoneal cavity, andan organic- and phosphate-removing stage, including at least one replaceable cartridge in the closed liquid flow loop, the cartridge containing material for removing organic compounds and phosphate from dialysate removed from the patient's peritoneal cavity.; The portable peritoneal dialysis system further includes a urea- and ammonia-removing stage, including at least one replaceable cartridge in the closed liquid flow loop, the cartridge containing material for removing urea and ammonia from dialysate removed from the patient's peritoneal cavity, the material being packed around semi-permeable hollow fibers with interior fiber walls that reject cations, thereby retaining cations in the dialysate.

Description

[0001] related application [0002] This application claims priority to US Provisional Application No. 61 / 198,102, filed November 3, 2008. [0003] The entire teachings of the above applications are incorporated herein by reference. Background technique [0004] Kidney dysfunction or failure, especially in advanced kidney disease, causes the body to lose its ability to shed water and minerals, excrete harmful metabolites, maintain acid-base balance, and control electrolyte and mineral concentrations within physiological ranges. Toxic uremic metabolic waste products, including urea, creatinine, uric acid, and phosphorus, accumulate in body tissues and can kill patients if they do not replace the filtering function of the kidneys. [0005] Dialysis is often used to remove these waste toxins and excess water, which replaces kidney function. In one type of dialysis treatment, hemodialysis, toxins are removed from the patient's blood externally in a hemodialysis machine. Blood p...

AI Technical Summary

Problems solved by technology

In general, current sorbent-based hemodialysis machines continuously replace these basic ions using additional pumps and connecting valves and control mechanisms, which add weight and complexity to the hemodialysis machine, and there is a similar analogue for peritoneal dialysis systems. question