Traditional Chinese medicine extract for treating ischemic heart disease and arrhythmia, and preparation method thereof

Abstract

The invention provides a traditional Chinese medicine extract for treating ischemic heart disease, and a preparation method thereof. The extract is prepared from 5-800 parts by weight of figwort root and 10-1500 parts by weight of honeysuckle as raw materials. Proven by experiments, the extract provided by the invention has obvious effects, can reduce the infarct size induced by myocardial ischemia after coronary artery ligation of rats, and can relieve arrhythmia caused by aconitine on mice, ouabin on guinea pigs and coronary artery ligation on rats. Therefore, the extract can be used for treating ischemic heart disease and arrhythmia.

Description

technical field [0001] The invention relates to the extraction of medicine and its preparation method, in particular to the extraction of traditional Chinese medicine and its preparation method. Background technique [0002] Coronary heart disease (CHD), referred to as coronary heart disease, is the most common heart disease. It refers to myocardial dysfunction and / or organic disease caused by coronary artery stenosis and insufficient blood supply. Therefore, it is also called ischemic cardiomyopathy (IHD). CHD / IHD is the most common form of heart disease. The World Health Organization classifies CHD / IHD as follows: (1) primary cardiac arrest; (2) angina pectoris; (3) myocardial infarction; (4) heart failure in ischemic heart disease; (5) arrhythmia. [0003] Epidemiological surveys show that various heart diseases can lead to sudden cardiac death (SCD), and CHD / IHD is one of the most important reasons. In western countries, coronary heart disease may account for 80% of th...

AI Technical Summary

Problems solved by technology

Modern pharmacological studies have shown that Mailuoning Compound Injection, which contains traditional Chinese medicines such as Scrophulariae Scrophulariae, Dendrobium, Achyranthes bidentata, and Honeysuckle, has an outstanding effect on thromboembolic diseases, and the combination of more than four drugs makes it effective in cardiovascular and cerebrovascular systems. Relatively increase fibrinolytic activity, reduce fibrinogen content, anti-thrombolytic, improve hemorheological characteristics, improve microcirculation, protect cardiovascular and cerebrovascular and tissues, etc. (Yu Feng, Jin Yitao, Qi Chunyu, Xie Wei, Shi Yuwen, Mailuoning Advances in pharmacological research of injections [J]. Chinese Journal of New Drugs, 2002, (12).), but these pharmacological activities only show that honeysuckle and Scrophulariaceae have compatibility and are the basis for treating cardiovascular and cerebrovascular diseases. The combination of the two is used for ischemic heart disease and arrhythmia, and the effective part of the treatment still needs further in-depth research

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