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Chinese medicinal compound preparation for treating hyperplasia of mammary glands and preparation method thereof

A technology of mammary gland hyperplasia and preparation, which is applied in the direction of medical formulas, medical preparations containing active ingredients, drug combinations, etc., can solve problems such as adverse reactions, induction of endometrial cancer, and easy recurrence, and achieve low recurrence rate and significant curative effect , no adverse effects

Inactive Publication Date: 2012-03-14
INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Hormone therapy for mammary gland hyperplasia can achieve the purpose of relieving pain and shrinking tumors, but it has adverse reactions. Many patients find it difficult to adhere to the medication, and it is easy to relapse after stopping the medication. Long-term use has the risk of inducing endometrial cancer

Method used

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Examples

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Effect test

Embodiment 1

[0011] A compound traditional Chinese medicine preparation for treating hyperplasia of mammary glands, comprising the following traditional Chinese medicine raw materials in the following weight ratio: Bupleurum 8, Radix Paeoniae Alba 8, Angelica 8, Poria cocos 8, Cyperus cyperi 13, Curcuma 8, Salvia miltiorrhiza 13, Prunella vulgaris 8, Gui branch 5.

[0012] The preparation method is to wash the above nine medicinal materials, mix them in proportion, add 5 times the total weight of the medicinal materials and decoct twice for 70 minutes each time, combine the two decoctions, filter, and concentrate to obtain 60°C It is a liquid extract with a specific gravity of 1.16.

Embodiment 2

[0014] A compound traditional Chinese medicine preparation for treating mammary gland hyperplasia, comprising the following traditional Chinese medicine raw materials in the following weight ratio: Bupleurum 10, Radix Paeoniae Alba 10, Angelica 10, Poria 10, Rhizoma Cyperi 15, Curcuma 10, Salvia miltiorrhiza 15, Prunella vulgaris 10, Gui Branch 6.

[0015] All the other are with embodiment 1.

Embodiment 3

[0017] A compound traditional Chinese medicine preparation for treating mammary gland hyperplasia, comprising the following traditional Chinese medicine raw materials in the following weight ratio: Bupleurum 12, Radix Paeoniae Alba 12, Angelica 12, Poria 12, Rhizoma Cyperi 17, Curcuma 12, Salvia 17, Prunella vulgaris 12, Gui Branch 7.

[0018] The preparation method is to wash the above-mentioned 9 medicinal materials, mix them in proportion, add 5 times of the total weight of the medicinal materials, and decoct 2 times with ethanol with a volume ratio of 75%, 70 minutes each time, combine the 2 decoctions, filter, and Concentrate to obtain a liquid extract with a specific gravity of 1.16 at 60°C.

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Abstract

The invention relates to a compound Chinese medicinal preparation for hyperplasia of mammary glands. The compound Chinese medicinal preparation comprises the following Chinese medicinal raw materials by weight: 8-12 grams of Chinese thorowax root, 8-12 grams of white paeony root, 8-12 grams of Chinese angelica, 8-12 grams of indian buead, 13-17 grams of nutgrass galingale rhizome, 8-12 grams of turmeric root-tuber, 13-17 grams of red-rooted salvia root, 8-12 grams of common selfheal fruit-spike and 5-7 grams of cassia twig. A preparation method of the compound Chinese medicinal preparation comprises the following steps of: cleaning the nine types of medicinal materials; mixing proportionally; adding water in an amount which is 5-7 times the total weight of the medicinal materials or 75 percent by volume of ethanol for decocting twice, every time for 70 minutes; combining decoction solutions obtained in the two times; filtering; and concentrating to obtain a liquid extract of which the specific weight is 1.16 at 60 DEG C. The compound Chinese medicinal preparation can be prepared into any pharmaceutical dosage form, such as tablets, capsules, granules, oral liquid, pills and syrup by adopting the conventional preparation process. The compound Chinese medicinal preparation for treating hyperplasia of mammary glands prepared with the method has a remarkable curative effect and low reoccurrence rate, is free from untoward reactions, and shows the advantages of traditional Chinese medicines on treating hyperplasia of mammary glands.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for treating mammary gland hyperplasia and a preparation method thereof, belonging to the field of traditional Chinese medicine preparations. Background technique [0002] Hyperplastic disease of breast (HDB) is a degenerative and progressive change in the structure of breast ducts and lobules. The World Health Organization collectively refers to "benign breast dysplasia" and believes that the disease is mainly caused by endocrine system disorders. Proliferative lesions that occur when hormones stimulate breast tissue for a long time. [0003] Hormone therapy for mammary gland hyperplasia can achieve the purpose of relieving pain and shrinking tumors, but it has adverse reactions. Many patients find it difficult to adhere to the medication, and it is easy to relapse after stopping the medication. Long-term use has the risk of inducing endometrial cancer. Chinese medicine tre...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K36/71A61P15/14
Inventor 吕爱平郑光吕诚姜淼杨静
Owner INST OF BASIC RES & CLINICAL MEDICINE CHINA ACAD OF CHINESE MEDICAL SCI
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