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Heart resurrection dripping pill production process

A production process and drop pill technology, which is applied in pill delivery, cardiovascular system diseases, plant raw materials, etc., can solve the problems of unsatisfactory curative effect of coronary heart disease angina pectoris, high frequency of angina pectoris attacks, and short duration, etc., to prolong the duration of drug action time, relieve precordial pain, and reduce the number of seizures

Active Publication Date: 2012-07-18
李晓云
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, the curative effect of drugs for treating angina pectoris of coronary heart disease is not ideal; the number of attacks of angina pectoris is relatively high, the duration of drug action effect is short, and the dosage is relatively large

Method used

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  • Heart resurrection dripping pill production process
  • Heart resurrection dripping pill production process
  • Heart resurrection dripping pill production process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The production process of Jiuxin Dropping Pills comprises the steps:

[0027] (1) Prepare raw materials: prepare raw materials according to the mass ratio of Rhizoma Chuanxiong, Salvia Miltiorrhiza and Borneolum: Rhizoma Chuanxiong: Salvia Miltiorrhiza: Borneolum=65:40:3;

[0028] (2) Mix Chuanxiong and Salvia miltiorrhiza, add water and decoct twice respectively, the first decoction is 2-3 hours, and the second decoction is 1.5-2.5 hours;

[0029] (3) Combine the solutions obtained after twice decocting in step (2), and when concentrated to 50° C., the relative density is 1.20-1.25;

[0030] (4) adding ethanol to the concentrated solution obtained after the concentration of step (3), the volume of added ethanol is 0.9-1.1 times of the concentrated solution volume, filtered and concentrated to obtain a clear paste;

[0031] (5) Take borneol, add ethanol until completely dissolved, and increase the solution;

[0032] (6) Get Polyethylene Glycol-6000, heating and meltin...

Embodiment 2

[0035] The difference between this embodiment and Example 1 is that the mass ratio of Chuanxiong, Danshen and Borneolum is: Chuanxiong: Danshen: Borneolum=85:60:9.

Embodiment 3

[0037] The difference between this embodiment and Example 1 is that the mass ratio of Chuanxiong, Danshen and Borneolum is: Chuanxiong: Danshen: Borneolum=70:45:7.

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Abstract

The invention discloses a heart resurrection dripping pill production process, which comprises the following step of: (1) preparing raw materials including szechuan lovage rhizome, red-rooted salvia root and borneol in the ratio of (65-85):(40-60):(3-9); (2) mixing szechuan lovage rhizome with red-rooted salvia root, and adding water for decocting twice; (3) combining solutions obtained by decocting twice in the step (2), and concentrating; (4) adding ethanol into a concentrated solution obtained by concentrating in the step (3), filtering and concentrating to obtain clear paste; (5) adding ethanol into borneol till the borneol is dissolved fully to obtain a solubilization liquid; (6) heating polyethyleneglycol-6000, and melting; and (7) mixing the clear paste obtained in the step (4), the solubilization liquid obtained in the step (5) and a polyethyleneglycol-600 melt obtained in the step (6), and stirring uniformly to obtain an intermediate. Due to the adoption of a heart resurrection dripping pill produced with the heart resurrection dripping pill production process, the attacking times of angina pectoris can be reduced effectively, the lasting time of a medicament is prolonged, and the using amount is small.

Description

technical field [0001] The invention relates to a medicine production process, in particular to a production process of Jiuxin Dropping Pills for coronary heart disease angina pectoris. Background technique [0002] Coronary heart disease is a common disease that seriously endangers people's health. It is divided into the following five types: hidden type, angina pectoris type, myocardial infarction type, heart failure type and sudden death type; the most common type is angina pectoris type, and the most serious type is both myocardial infarction and sudden death type. types. [0003] Among them, tubular atherosclerotic heart disease angina pectoris is a common disease among middle-aged and elderly people, and its morbidity and mortality rank first. The curative effect of the drugs used in the prior art for treating angina pectoris of coronary heart disease is not ideal; the number of episodes of angina pectoris is relatively high, the duration of drug action and effect is ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/537A61K9/20A61P9/10
Inventor 李晓云
Owner 李晓云
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