Chinese medicinal compound preparation for treating ischemic cerebrovascular disease and preparation method thereof

A technology of cerebrovascular disease and compound preparation, which is applied in the field of compound preparation of traditional Chinese medicine for the treatment of ischemic cerebrovascular disease and its preparation, which can solve the problems of large side effects, high price, and no ischemic cerebrovascular disease.

Inactive Publication Date: 2012-07-25
SHANDONG ACAD OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Pre-drug treatment mostly uses western medicine, which has relatively large side effects after treatment, and some have better effects but are expensive
It has been reported in the literature that ischemic cerebrovascular disease is caused by vascular stenosis or blockage, but at present, there is no better traditional Chinese medicine compound preparation for the treatment of ischemic cerebrovascular disease.

Method used

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  • Chinese medicinal compound preparation for treating ischemic cerebrovascular disease and preparation method thereof
  • Chinese medicinal compound preparation for treating ischemic cerebrovascular disease and preparation method thereof
  • Chinese medicinal compound preparation for treating ischemic cerebrovascular disease and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The weight proportion of used Chinese medicinal material raw material is:

[0021]

[0022] The preparation method is as follows:

[0023] Step 1: Prepare angelica, chuanxiong, calamus, walnut kernel, ginseng, astragalus, polygala in different weights;

[0024] Step 2: Take the medicinal materials Chuanxiong and Angelica, crush them through a 10-mesh sieve, add 5 times the weight of the medicinal materials in water after mixing, soak for 4 hours, heat to extract the volatile oil, filter after extracting the oil, and obtain the medicinal residue A and the filtrate, and concentrate the filtrate to a density of 1.01, add ethanol to make the concentration 70%, refrigerate for 18 hours, filter, and the filtrate is set aside;

[0025] Step 3: Crush the medicinal material ginseng into fine powder, and sieve it for later use;

[0026] Step 4: take the medicinal material walnut kernel and heat it at 150°C for 1.5 hours to inactivate the enzyme, crush the walnut kernel after...

Embodiment 2

[0031] The weight proportion of used Chinese medicinal material raw material is:

[0032]

[0033] Preparation:

[0034] Step 1: Prepare angelica, chuanxiong, calamus, walnut kernel, ginseng, astragalus, polygala in different weights;

[0035] Step 2: Take the medicinal materials Chuanxiong and Angelica, crush them through a 10-mesh sieve, add 8 times the weight of the medicinal materials in water after mixing, soak for 4 hours, heat to extract the volatile oil, filter after extracting the oil, and obtain the medicinal residue A and the filtrate, and concentrate the filtrate to a density of 1.50, add ethanol to make the concentration 70%, refrigerate for 27 hours, filter, and the filtrate is set aside;

[0036] Step 3: Crush the medicinal material ginseng into fine powder, and sieve it for later use;

[0037] Step 4: take the medicinal material walnut kernel and heat it at 150°C for 1.5 hours to inactivate the enzyme, crush the walnut kernel after the enzyme inactivation ...

Embodiment 3

[0042] The weight proportion of used Chinese medicinal material raw material is:

[0043]

[0044] Preparation:

[0045] Step 1: Prepare angelica, chuanxiong, calamus, walnut kernel, ginseng, astragalus, polygala in different weights;

[0046] Step 2: Take the medicinal materials Chuanxiong and Angelica, crush them through a 10-mesh sieve, add 10 times the weight of the medicinal materials in water after mixing, soak for 4 hours, heat to extract the volatile oil, filter after extracting the oil, and obtain the medicinal residue A and the filtrate, and concentrate the filtrate to a density of 1.30, add ethanol to make the concentration 70%, refrigerate for 35 hours, filter, and use the filtrate for later use;

[0047] Step 3: Crush the medicinal material ginseng into fine powder, and sieve it for later use;

[0048] Step 4: take the medicinal material walnut kernel and heat it at 150°C for 1.5 hours to inactivate the enzyme, crush the walnut kernel after the enzyme inactiv...

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Abstract

The invention provides a Chinese medicinal compound preparation for treating ischemic cerebrovascular disease and a preparation method thereof. The Chinese medicinal compound preparation is characterized by comprising the following Chinese medicinal raw materials in parts by weight: 50 to 250 parts of Chinese angelica, 60 to 180 parts of hemlock parsley, 50 to 200 parts of grassleaf sweelflag rhizome, 150 to 500 parts of walnut kernels, 50 to 150 parts of ginseng, 100 to 300 parts of astragalus mongholicus, and 60 to 200 parts of thinleaf milkwort root-bark, wherein the Chinese medicaments are used as raw materials to prepare the preparation. The Chinese medicinal compound preparation has the functions of promoting qi to activate blood, tonifying kidney and enhancing wisdom, can be clinically used for treating symptoms, such as amnesia and dementia caused by renal deficiency and blood stasis, ecmnesia, soreness and weakness of waist and knees, nocturnal polyuria, dry stool, dry skin, even glazed expression, recurrent mania, dark tongue, ecchymosis and petechia, thready and sluggish pulse and the like.

Description

Technical field: [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a compound traditional Chinese medicine preparation for treating ischemic cerebrovascular disease and a preparation method thereof. Background technique: [0002] Cerebrovascular disease is a common disease of the elderly, with the characteristics of high mortality and high disability rate. According to the different causes, it can be divided into ischemic and hemorrhagic cerebrovascular diseases, and the incidence of the former accounts for about 85% of cerebrovascular diseases. The fundamental mechanism and final outcome of ischemic cerebrovascular disease are brain tissue ischemia and hypoxia. The current hotspots and difficulties in acute phase treatment research include: ① specific treatment, focusing on improving blood flow (thrombolysis, anticoagulation, antiplatelet, defibrosis, etc.) and neuroprotection; ② non-specific treatment, focus...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61P9/10
Inventor 孙蓉韩涛吕莉莉曹志群孙建光黄伟龚彦胜
Owner SHANDONG ACAD OF CHINESE MEDICINE
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