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Traditional Chinese medicine composition for treating conjunctivitis by external use and applications of composition

A composition and technology for conjunctivitis, applied in the field of traditional Chinese medicine compositions, can solve the problems of decreased tear film stability, affecting the adhesion function of tear film mucus protein, and not providing conjunctivitis Chinese medicine compositions, etc.

Active Publication Date: 2012-10-31
ZHUHAI QLWEL BIO TECH LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The current conventional treatment for acute conjunctivitis is to use frequent eye drops of various antibiotics or antiviral drugs. Although these drugs have significant curative effect, they all have toxic effects on corneoconjunctival epithelial cells
In addition, frequent eye drops affect the adhesion function of the tear film mucus protein to the ocular surface epithelium, which reduces the stability of the tear film, and then causes discomfort such as eye burning and dryness.
In addition, the preservatives in the eye drops are also toxic to the corneal and conjunctival epithelium, which changes the permeability of the epithelial cells. The punctate shedding of the corneal epithelium and the shortening of the tear film break-up time (BUT) may be related to this
[0004] The present prior art does not provide a kind of Chinese medicine composition for the external treatment of conjunctivitis

Method used

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  • Traditional Chinese medicine composition for treating conjunctivitis by external use and applications of composition
  • Traditional Chinese medicine composition for treating conjunctivitis by external use and applications of composition
  • Traditional Chinese medicine composition for treating conjunctivitis by external use and applications of composition

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0055] Experimental Example 1 Clinical Experimental Research

[0056] 1 clinical data

[0057] 1.1 General information

[0058] Patients with acute conjunctivitis: 58 males and 68 females; aged 8 to 89 years, with an average age of (40.6±18) years.

[0059] 1.2 Diagnostic criteria for acute conjunctivitis

[0060] (1) Acute onset, often with contact history, easy to spread;

[0061] (2) Subjective symptoms: red eyes, foreign body sensation, photophobia, tearing, increased secretions;

[0062](3) Check the symptoms: redness and swelling of the eyelids, conjunctival hyperemia, edema, or subconjunctival spots, sheet hemorrhages or papillary follicles.

[0063] 1.3 Eye ultrasonic atomization method:

[0064] Get the medicinal liquid prepared in Example 1, put every 20ml into the ultrasonic atomizer, connect it with the atomizing tube, and make the medicinal liquid form atomized molecules through ultrasonic vibration to directly act on the eyes. Before the treatment, the conj...

Embodiment 1

[0094] Scutellaria baicalensis 20g Coptidis 18g Houttuynia cordata 15g

[0095] 15g of nasturtium, 15g of mint, 1g of borneol;

[0096] Except for the five flavors of borneol, use 10 times the amount of water to decoct 3 times, 1 hour each time, combine the decoction, filter, concentrate the filtrate, centrifuge at 3000r / min for 15min, take the supernatant, add borneol to the supernatant, Prepare 100ml liquid medicinal solution.

[0097] Specific usage: Take 20ml of liquid medicine, put it into an ultrasonic atomizer container, connect it with an atomizing tube, and make the medicine form atomized molecules through ultrasonic vibration to directly act on the eyes. Before the treatment, the conjunctival sac should be flushed first, and then the patient should be instructed to open both eyes, hold the nebulizer tube and aim at the eyes for the nebulization treatment of traditional Chinese medicine. 1 course of treatment, the curative effect was counted after a course of treatm...

Embodiment 2

[0099] Scutellaria baicalensis 20g Coptidis 20g Houttuynia cordata 20g Nasturtium 20g Mint 15g borneol 0.9g;

[0100] Except for the five flavors of borneol, use 10 times the amount of water to decoct 3 times, 1 hour each time, combine the decoction, filter, concentrate the filtrate, centrifuge at 3000r / min for 15min, take the supernatant, add borneol to the supernatant, Prepare 100ml liquid medicinal solution.

[0101] Specific usage: Take 20ml of liquid medicine, put it into an ultrasonic atomizer container, connect it with an atomizing tube, and make the medicine form atomized molecules through ultrasonic vibration to directly act on the eyes. Before the treatment, the conjunctival sac should be flushed first, and then the patient should be instructed to open both eyes, hold the nebulizer tube and aim at the eyes for the nebulization treatment of traditional Chinese medicine. 1 course of treatment, the curative effect was counted after a course of treatment.

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Abstract

The invention provides a traditional Chinese medicine composition for treating conjunctivitis by external use and applications of the composition. The traditional Chinese medicine composition for treating conjunctivitis by external use is characterized by comprising the following bulk drugs in weight part: 10-50 parts of scutellaria baicalensis, 8-40 parts of coptis chinensis, 5-35 parts of cordate houttuynia, 5-35 parts of trollflower and 5-35 parts of mentha haplocalyx. Selectively, the traditional Chinese medicine composition for treating conjunctivitis by external use also comprises borneol, and the invention also provides eye-drops preparations prepared from the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the raw materials of scutellaria baicalensis, coptis chinensis, cordate houttuynia, trollflower and the like. The traditional Chinese medicine composition provided by the invention has obvious effects of treating conjunctivitis, and the indexes such as conjunctival congestion, edema, secretion, ST, lacrimal river height and the like are obviously different before and after the treatment by the traditional Chinese medicine composition.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to an external traditional Chinese medicine composition for treating conjunctivitis. Background technique [0002] Conjunctivitis is a common disease in ophthalmology. Since most of the conjunctiva is in direct contact with the outside world, when the defense ability of the ocular surface is weakened or external pathogenic factors are strengthened, it will cause inflammation of the conjunctival tissue, which is characterized by conjunctival vascular congestion, edema and Increased secretions. Acute conjunctivitis can be caused by viral or bacterial factors and is highly contagious. Chronic conjunctivitis can be caused by improper treatment during the recovery period of acute conjunctivitis, environmental factors, chemical stimuli, and allergic factors. In acute conjunctivitis, pathogenic microorganisms can directly invade the conjunctival epithelial cells, produce an i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/78A61P27/02
Inventor 白杰
Owner ZHUHAI QLWEL BIO TECH LTD
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