Preparation method of apostichopus japonicus slow-release type compound immunopotentiator
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An immune enhancer and slow-release technology, which is applied in the field of preparation of sea cucumber slow-release compound immune enhancer, can solve the problems of sea cucumbers that cannot eat the dose of medicine, small particles with large specific surface area, and farmers are not easy to operate, etc. Achieve the effects of promoting healthy and sustainable development, sinking quickly, and reducing common diseases of sea cucumbers
Inactive Publication Date: 2012-11-28
JINZHOU MEDICAL UNIV
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At present, most of the Chinese herbal medicines orally used in sea cucumber cultivation are simply crushed and then mixed with conventional feed. The disadvantage is that the medicine has a light specific gravity and sinks slowly in the water. Due to the slow feeding of sea cucumbers, it takes a while to reach the bottom and be eaten by sea cucumbers. Time, coupled with the large specific surface area of small particles, during this period, most of the medicinal ingredients are dissolved in the water, so that sea cucumbers cannot take enough dosage of medicine, wasting medicine, spoiling the water quality, and affecting the actual effect
Some existing slow-release materials often have the defects of high cost, complicated process, and difficult operation by ordinary farmers
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[0026] 1. Selection and preparation of pharmaceutical ingredients
[0027] According to the compatibility theory of traditional Chinese medicine and the experimental results of modern pharmacology, combined with the local resources of traditional Chinese medicine, the prescription is carefully formulated, which fully exerts the synergistic and complementary effects between the medicines, which is significantly better than a single prescription; the pharmacological effects of each component are as follows:
[0028] (1) Astragalus Astragalus has the effects of invigorating qi and solidifying the surface, diuresis and detoxification, draining pus, astringing sores and promoting granulation, and can promote the specific and non-specific immune system of animals, which is specifically manifested in that it can significantly increase the total number of white blood cells in the blood , promote the phagocytosis and bactericidal ability of neutrophils and macrophages, anti-ulcer, etc.,...
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Abstract
The invention relates to a preparation method of an apostichopus japonicus slow-release type compound immunopotentiator. Radix astragali, codonopsis pilosula, ledebouriella root, white atractylodes rhizome, honeysuckle, forsythia, semen ziziphi spinosae, vitamin C, pine needle powder, earthworm powder, scandent hop and red-knees herb are taken in part by weight, clinoptilolite powder and flour are taken as slow release and bonding materials, and the medicaments are micro-particle powdery. The medicaments are added according to the weight ratio of 2 percent of stichopus japonicus feed every day and are uniformly mixed to feed. The preparation method has the beneficial effects that the compatibility is reasonable, the collaborative and complementary action among the medicaments is fully displayed, the immunity of apostichopus japonicus is remarkably enhanced, and the occurrence of apostichopus japonicus common diseases is greatly reduced; no toxic and side effect, no medicament resistance and no pollution exist; the medicaments have the nutritional value and are good in feeding attraction, the apostichopus japonicus feed intake can be improved, the tissue cell division is prompted, and the effect of promoting the growth is realized; through a slow release agent, the medicaments can quickly sink and are less in melting loss in water, so that the medicament waste is reduced, the cost is saved, and the water quality is not damaged; and the apostichopus japonicus slow-release type compound immunopotentiator has the positive significance on effectively preventing the apostichopusjaponicus diseases, improving the production level of pollution-free seeds, ensuring the food safety, maintaining the ecological environment and promoting the sustainable health development of the trepang breeding industry.
Description
technical field [0001] The invention relates to a preparation method of a japonicus slow-release compound immune enhancer which can improve the disease-resistant ability of sea cucumbers and has high utilization efficiency. [0002] Background technique [0003] sea cucumber ( Apostichopus japonicus ) belongs to the phylum Echinodermata, the class Holothuridae, and the family Apostichopidae. Naturally distributed in my country's Bohai Sea, Yellow Sea and other waters. Because sea cucumber has extremely high medicinal and nutritional value, the market demand space is large, thus driving the development of sea cucumber breeding industry. [0004] With the rapid expansion of the scale of sea cucumber intensive farming, the problem of diseases is becoming more and more serious. Apostichopus japonicus diseases are mainly primary and secondary bacterial infectious diseases, especially rotting skin syndrome in the overwintering seedling preservation period and adult ginseng b...
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