Traditional Chinese prescription for treating hyperglycemia and preparation method thereof

A high blood sugar, prescription technology, applied in the field of medicine, can solve the problems of unsuitable long-term use, toxic and side effects, and the effect is not very obvious.

Inactive Publication Date: 2013-05-08
NORTHWEST A & F UNIV
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  • Description
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Problems solved by technology

Although the above-mentioned drugs have a certain effect on the treatment of diabetes, their effects are not very obvious in clinical practice. Some drugs also have toxic side effects on patients. For example, the most serious side effect of biguanide hypoglycemic drugs is to cause lactic acidosis, and death after the occurrence The rate is 50%, not suitable for long-term use

Method used

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  • Traditional Chinese prescription for treating hyperglycemia and preparation method thereof
  • Traditional Chinese prescription for treating hyperglycemia and preparation method thereof

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Experimental program
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Effect test

Embodiment Construction

[0024] Below in conjunction with specific embodiment technical scheme of the present invention is described in further detail animal experiment

[0025] Pharmacodynamic test and acute toxicological test on the prepared water decoction.

[0026] Pharmacodynamic test

[0027] 1 material

[0028] 1.1 Animals

[0029] 240 Kunming mice, SPF grade, weighing (20±2) g, male and female, were provided by the Experimental Animal Center of Xi'an Jiaotong University School of Medicine. Animal certificate number: SCXK (Shaanxi) 2007-001.

[0030] 1.2 Drugs and reagents

[0031] The prescription is composed of Yaowang tea, privet leaves and persimmon leaves, all of which are collected from Taibai Mountain in the Qinling Mountains. Referring to "Chinese Medicine Pharmacological Experimental Methodology" edited by Li Yikui, the dose of human medicine was converted into the dose of mice, and a water decoction was prepared, sterilized by high-pressure steam (110°C, 15min), stored at 4°C, an...

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Abstract

The invention discloses a traditional Chinese prescription for treating hyperglycemia and a preparation method thereof. Calculated according to one-time oral dose of an adult who is 60kg in weight, the traditional Chinese prescription is prepared from the following crude drugs by weight: 10-20g of taibai bushy dasiphora leaf, 10-15g of glossy privet leaf, and 10-15g of persimmon leaf. Pharmacological tests show that the prescription has significant effect of reducing blood sugar, and is safe and innocuous.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a traditional Chinese medicine prescription for treating hyperglycemia and a preparation method thereof. Background technique [0002] Medically, when the blood sugar is higher than the normal range (fasting blood sugar normal value 4.0-6.1mmol / L) on an empty stomach (no sugar or any sugar-containing food intake within 8 hours), it is called hyperglycemia. If the blood sugar is high two hours after a meal If it is less than 7.8mmol / L, it can also be called hyperglycemia. Diabetes mellitus is an endocrine disease with glucose metabolism disorder as the main symptom. The pathogenesis is insufficient insulin secretion or abnormal insulin receptor function in patients. The clinical manifestations are elevated fasting or postprandial blood sugar, diabetes and hyperlipidemia. rate is increasing year by year. Although hyperglycemia is not a disease, nor is it completely equivalent to d...

Claims

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Application Information

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IPC IPC(8): A61K36/73A61P3/10
Inventor 康永祥刘建军季志平江跃德王晶钰
Owner NORTHWEST A & F UNIV
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