53 results about "Glycemic efficacy" patented technology

The invention discloses a sea cucumber protein heptapeptide with functions of reducing blood pressure and blood sugar and application of the sea cucumber protein heptapeptide, and belongs to the technical field of bioactive peptide biology. The amino acid sequence of the sea cucumber protein heptapeptide is LPPGPFP. The sea cucumber protein heptapeptide can significantly inhibit the activity of ACE through a competitive inhibition mode, tolerates the gastrointestinal tract digestion environment, also has DPP-IV inhibition activity, can relieve hypertension and type 2 diabetes mellitus at the same time, and has an application value in preparation of products with the efficacy of reducing blood pressure and blood sugar due to multiple functions of the sea cucumber protein heptapeptide. The sea cucumber protein heptapeptide provided by the invention can significantly inhibit the activity of ACE through a competitive inhibition mode, has DPP-IV inhibition activity, has the characteristics of simple structure, safety, strong activity and the like, and has a wide application prospect.

The invention discloses a small-molecule active peptide, a composition and application of the small-molecule active peptide in preparation of a product with antioxidant and hypoglycemic effects, and belongs to the technical field of biological active peptides. The amino acid sequence of the small molecule active peptide is at least one of DQFPR, LDQFPR and SYGLPR. According to the invention, a plurality of small molecule active peptides with antioxidant and hypoglycemic effects are obtained by separating and purifying peanut protein, the identified peptide fragment sequence is chemically synthesized, and the antioxidant activity and hypoglycemic activity of a single peptide fragment and a compound peptide fragment of the synthesized peptide fragment are detected. The small molecule active peptide and the compound peptide fragment thereof have good effects of scavenging free radicals and inhibiting alpha-glucosidase and alpha-amylase, and have good application prospects in preparation of products with antioxidant and hypoglycemic effects; and a foundation is laid for high-added-value utilization of the peanut protein and promotion of research, development and application of functional active peptides.

The invention discloses a small-molecule active peptide with antioxidant and hypoglycemic effects, a composition and application, and belongs to the technical field of biological active peptides. The amino acid sequence of the small molecule active peptide with the antioxidant and blood sugar reducing effects is at least one of FSNAPRL, QFGRLY and SVPGHF. According to the invention, a plurality of micromolecular active peptides with antioxidant and hypoglycemic effects are extracted from walnut meal, the obtained peptide fragment sequence is subjected to molecular docking and chemical synthesis, and the antioxidant activity and hypoglycemic activity of a single peptide fragment and a compound peptide fragment of the synthesized peptide fragment are verified. The active peptide and the compound peptide fragment thereof have good DPPH and ABTS clearance rate and alpha-glucosidase and alpha-amylase inhibition ability, so that the active peptide and the compound peptide fragment thereof have good application prospects in preparation of products with antioxidant and hypoglycemic effects, and a foundation is laid for comprehensive utilization of walnut meal byproducts and promotion of research, development and application of functional active peptides.

The invention relates to a lactic acid bacterium capable of reducing fat, resisting inflammation and reducing blood sugar, which is classified and named as pediococcus acidilactici XJ335, and is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number is CGMCC No.30093, the preservation date is March 22, 2024, and the preservation address is No.3, Yard 1, Beichen West Road, Chaoyang District, Beijing. The strain can achieve the fat reducing effect by adjusting the abundance of intestinal flora; the levels of IL-6 and TNF-alpha in serum of diabetic mice are remarkably improved through regulation, so that the anti-inflammatory effect is achieved; various cardiovascular diseases of atherosclerosis are prevented by adjusting the levels of TC, TG, HDL-C and LDL-C; by reducing FINS and HOMA-IR levels and improving HOMA-IS, HOMA-beta and QUICKI value levels, insulin resistance of a body is reduced, insulin sensitivity and pancreas islet beta cell functions of the body are improved, gene expression related to blood sugar regulation is regulated, and an excellent blood sugar reducing effect is achieved in the body.

The invention discloses a bioactive peptide with antioxidant and hypoglycemic effects, a preparation and application thereof, and belongs to the technical field of bioactive peptides. The bioactive peptide provided by the invention is as shown in at least one of SEQ ID NO: 1 to SEQ ID NO: 4. Degreased shiny-leaved yellowhorn meal is used as a raw material, after high-temperature heat treatment and ultrahigh-pressure pretreatment are performed, the bioactive peptide with antioxidant and hypoglycemic effects is separated through enzymolysis, ultrafiltration and a liquid chromatography separation technology in combination with a bioinformatics technology, and components and sequences of the bioactive peptide are preliminarily identified through a liquid chromatography-mass spectrometry technology. And carrying out chemical synthesis according to the identified peptide fragment sequence to obtain four bioactive peptides with antioxidant and hypoglycemic effects. Through detection, the peptide fragments and the compound peptide fragments thereof have good alpha-glucosidase and alpha-amylase inhibitory activity, and have good application prospects in preparation of products with antioxidant and hypoglycemic effects.

The invention discloses a marine-derived bioactive peptide with a blood sugar reducing effect, a preparation and application, and belongs to the technical field of bioactive peptides. The amino acid sequence of the bioactive peptide is at least one of FYP, FPF and YAPFPK. Three bioactive peptides with the blood sugar reducing effect are separated and purified from oysters through enzymolysis, ultrafiltration, gel chromatography, liquid chromatography-mass spectrometry and bioinformatics technologies. According to the present invention, chemical synthesis is performed according to the identified peptide fragment sequence, the hypoglycemic activity of the synthesized single peptide fragment and the compounded peptide fragment is detected, and the bioactive peptides have good alpha-glucosidase inhibition activity, such that the bioactive peptides have good application prospects in the preparation of the products with the hypoglycemic effect, and can be widely used in the preparation of the products with the hypoglycemic effect. And a foundation is laid for high value-added utilization of oysters and promotion of research, development and application of functional active peptides.

The invention discloses a cane molasses extract with a blood sugar reducing effect as well as a preparation method and application thereof, and belongs to the field of functional foods. According to the invention, cane molasses is subjected to dissolution, centrifugation, ultrafiltration impurity removal, desalination and nanofiltration concentration, and is mixed with calcium chloride, so that the cane molasses extract with the effect of reducing blood sugar is prepared. Experimental results prove that the cane molasses extract prepared by the invention has the characteristics of low glycemic index (GI), carbohydrate digestive enzyme inhibition, high temperature resistance, long-term storage resistance and the like, can also effectively repair pancreas and liver injury and regulate intestinal flora, and has a comprehensive hypoglycemic effect. The food with low glycemic index is prepared on the basis of the high sucrose carrier for the first time, and the food has sweet taste and the function of reducing blood sugar. The invention provides a new raw material scheme for the preparation of dietary supplement food and hypoglycemic drugs for hyperglycemia people, and has prominent practical application value and wide application prospect.

The application discloses application of Xintong preparation in preparation of a medicine for treating diabetes and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The Xintong preparation is prepared from 13 raw medicinal materials of Huangqi, Gegen, Danshen, Dangshen, Maidong, Heshouwu, Yinyanghuo, Dangui, Zaokesheng, Haizao, Kelp, Muli and Zhishi, has the effects of benefiting qi and activating blood, reducing phlegm and dredging collaterals. Pharmacodynamic experiments show that the Xintong preparation has the effect of reducing blood sugar, can effectively improve the physical conditions of polydipsia, polyphagia, polyuria and emaciation and lack of strength of an animal model of diabetes, significantly reduces the fasting blood sugar and serum insulin level, improves the oral glucose tolerance, has a definite treatment effect on type II diabetes, and expands the clinical application range of the Xintong preparation, and has a wide market application prospect.

The invention relates to application of lactobacillus acidophilus LA85 in preparation of a product with a blood sugar reducing effect. The brand new application of the lactobacillus acidophilus LA85 strain is developed, namely the lactobacillus acidophilus LA85 strain is used for inhibiting alpha-glucosidase, reducing blood sugar and improving diabetes mellitus, and tests prove that the food intake, the water intake and the urine volume of a mouse with type II diabetes mellitus can be effectively controlled after intervention of the LA85 strain, and the weight value of the mouse is stabilized; the glucose absorption and metabolism capability of diabetic mice is effectively improved, and continuous damage of pancreatic beta cell functions is retarded; the blood lipid level disorder state of the mouse with the type II diabetes mellitus is improved; the inflammation level of a mouse body with type II diabetes mellitus is reduced, and the immunity is improved; and a very good improvement and recovery effect is achieved on abundance and diversity reduction of intestinal flora of the type II diabetes mellitus mice.

The invention belongs to the technical field of medicinal chemistry, and discloses an indolone derivative containing a triazole structure as well as a preparation method and application of the indolone derivative. The indolone derivative has a structural formula as shown in a formula (I): # imgabs0 #, wherein R represents a substituted or unsubstituted phenyl group. The compound can effectively inhibit alpha-glucosidase, and can be used for preparing related products for treating / preventing diabetes mellitus to play a role in reducing blood sugar.

The invention belongs to the technical field of pet foods, and particularly relates to a pet snack with a blood sugar reducing effect. The pet snack comprises the following raw materials in parts by weight: 30-35 parts of starch, 5-8 parts of pea protein, 35-40 parts of meat, 12-15 parts of glycerol, 8-10 parts of calcium carbonate, 1-3 parts of vegetable oil, 2-5 parts of fibers, 0.1-0.2 part of potassium sorbate, 2-5 parts of earthworm powder, 2-5 parts of moringa oleifera leaf protein peptide and 1-4 parts of guava extract. The earthworm powder, the moringa oleifera leaf protein peptide and the guava extract are combined for use, the postprandial blood sugar of the pets can be effectively reduced, the peak value of the postprandial blood sugar of the pets is effectively reduced, and therefore the risk that the pets have continuous hyperglycemia after meals is reduced, and harm to the body health of the pets is reduced.

The invention discloses a fish-derived active peptide with antioxidant and hypoglycemic effects, a preparation and application, and belongs to the technical field of biological active peptides. The fish-derived active peptide with the effects of resisting oxidation and reducing blood sugar is at least one of peptide fragments with amino acid sequences as shown in SEQ ID NO: 1-SEQ ID NO: 3. According to the invention, three active peptides with antioxidant and hypoglycemic effects are extracted from salmon by-products by adopting protease enzymolysis, LC-MS / MS, a bioinformatics method and other methods, and the active peptides have high DPPH clearance rate, ABTS free radical clearance rate and alpha-glucosidase and alpha-amylase inhibition rate. Therefore, the compound has an important application prospect in the development of products with the effects of resisting oxidation and reducing blood sugar.

The present invention discloses a sea cucumber protein heptapeptide with blood pressure and blood sugar lowering functions and its application, belonging to the field of active peptide biotechnology. The amino acid sequence of the sea cucumber protein heptapeptide is LPPGPFP. The sea cucumber protein heptapeptide can significantly inhibit the activity of ACE through a competitive inhibition mode, tolerate the gastrointestinal digestion environment, and also has DPP-IV inhibitory activity, playing a role in alleviating both hypertension and type 2 diabetes. Its multiple functions make it have application value in the preparation of products with blood pressure and blood sugar lowering effects. The sea cucumber protein heptapeptide involved in the present invention can significantly inhibit the activity of ACE through a competitive inhibition mode, and at the same time has DPP-IV inhibitory activity. It has the characteristics of simple structure, safety, strong activity, etc., and has broad application prospects.

The invention discloses a tartary buckwheat compound with a blood sugar reducing effect and a preparation method and application thereof, tartary buckwheat is used as a main raw material and is subjected to water extraction, and an amino acid surfactant is added in the water extraction process, so that the permeability of cell walls can be effectively improved; flavonoid compounds, polyphenol compounds and proteins in cells are effectively dissolved out, and the extraction rate of active ingredients in the tartary buckwheat is increased; then the leach liquor is fermented by compounding Witzia ciliaris and Aspergillus niger, so that the content of active ingredients in the leach liquor is increased, and the effect of reducing blood sugar is further improved; the tartary buckwheat residues are subjected to combined treatment by adopting shearing homogenization and enzymolysis, and are further treated by adopting carboxymethyl cellulose, so that the viscosity of dietary fiber components is increased, the diffusion movement of glucose and amylase is favorably bound, and the auxiliary blood sugar reducing effect of the tartary buckwheat residues is further improved.

The invention provides a DPP-IV activity inhibitory peptide as well as a preparation method and application thereof, and belongs to the technical field of active peptides. The DPP-IV activity inhibitory peptide provided by the invention comprises at least one of amino acid sequences as shown in SEQ ID NO. 1 to SEQ ID NO. 4. According to the present invention, the DPP-IV activity inhibition peptide having effects of significant DPP-IV activity inhibition and blood sugar reducing is obtained through separation and purification from corn germ meal for the first time, wherein IC50 of LSPY, AGFAGDPR, ENPILQPY and IIPY on inhibition of DPP-IV are respectively 0.9385 mg / mL, 1.293 mg / mL, 3.177 mg / mL and 3.491 mg / mL. The DPP-IV activity inhibitory peptide provided by the invention can be used as an additive of products with the function of reducing blood sugar, such as food and medicines.

The invention discloses a collagen peptide with a blood sugar reducing effect as well as a preparation method and application of the collagen peptide. According to the preparation method provided by the invention, the zymolyte with strong DPP-IV inhibition activity is prepared, and the DPP-IV inhibition rate of the zymolyte under the final concentration of 1mg / mL reaches 69% (the IC50 value is 500mu g / mL); the zymolyte is rich in polypeptide consisting of 4-9 amino acid residues, and the content of the polypeptide accounts for 45%; animal experiments prove that the zymolyte can regulate fasting blood-glucose of mice with type 2 diabetes, improve the oral glucose tolerance and protect the liver. The preparation method provided by the invention is simple in process, enzymolysis controlled release of the target polypeptide is realized, the whole process flow can meet food-grade requirements, and the preparation method can be applied to health-care products and foods related to blood sugar reduction.

The invention relates to the technical field of biological medicine, in particular to a composition for improving blood sugar, a mulberry twig extract solid beverage and a preparation method of the mulberry twig extract solid beverage, in particular to a novel plant composite solid beverage for assisting in reducing blood sugar and a preparation method of the novel plant composite solid beverage. Xylitol, citric acid and sweet orange essence are used as auxiliary materials. The mulberry twig extract composite solid beverage capable of assisting in reducing blood sugar provided by the invention is prepared by optimally designing and reasonably combining various plant extracts serving as raw materials, plant active ingredients in the formula have a synergistic promotion effect and have a remarkable effect of assisting in reducing blood sugar, and the solid beverage is simple in preparation process, free of any chemical medicines and hormones, free of toxic and side effects and free of toxic and side effects. The problem that an existing medicinal and edible preparation for diabetes causes adverse effects on the health of diabetics is solved. The method has a wide product market, and research on remarkable economic benefits can be obtained.

The present invention provides a diglyceride oil with hypoglycemic effect and a preparation method thereof, which relates to the technical field of functional oil processing. The preparation method comprises the following steps: mixing seabuckthorn seed oil, Acer truncatum Bunge seed oil, rapeseed oil, corn oil and high-oleic acid peanut oil, adding glycerol and water to obtain material A; adding Pseudomonas cepacia lipase and Candida antarctica lipase B to material A for a primary reaction to obtain material B; adding Candida lipolytica lipase and Candida antarctica lipase B to material B for a second reaction to obtain material C; adding Thermomyces lanuginosus lipase to material C for a third reaction to obtain material D; and treating the reacted material D to obtain the diglyceride oil. The diglyceride oil prepared by the present invention has a good effect in reducing blood sugar.

The invention belongs to the technical field of fermentation, and particularly relates to medicinal and edible fermentation liquor with a blood sugar reducing effect as well as a preparation method and application of the medicinal and edible fermentation liquor. The fermentation liquor is prepared from the following components in parts by weight: 50 to 75 parts of fructus corni, 45 to 65 parts of stigma croci, 40 to 60 parts of fructus physalis pubescentis, 35 to 50 parts of rumex hanus, 13 to 20 parts of an enzyme preparation and 0.17 to 0.25 part of a leavening agent. The obtained fermentation liquor has the effect of inhibiting alpha-glucosidase through in-vitro verification, the fasting blood glucose level of rats with type 2 diabetes mellitus can be reduced through rat experiment verification, and the effect of reducing blood glucose can be achieved through a PI3K / Akt channel.

This invention provides *Pediococcus lactis* SHI03 and its application in alleviating insulin resistance and type 2 diabetes, belonging to the field of microbial technology. This invention provides *Pediococcus lactis* SHI03, with accession number CCTCC No: M 20242686, and confirms that this strain possesses in vitro α-glucosidase inhibitory activity, exhibiting excellent probiotic and hypoglycemic effects. This invention further provides microbial products containing *Pediococcus lactis* SHI03, including *Pediococcus lactis* SHI03 fermentation broth, *Pediococcus lactis* SHI03 fermentation supernatant, and *Pediococcus lactis* SHI03 cells, and their applications in alleviating high-fat diet-induced insulin resistance and reducing fasting blood glucose in type 2 diabetic mice.

The invention relates to a polypeptide with a blood sugar reducing effect. The amino acid sequence of the polypeptide is selected from one of IPVIA, IPVA, IPTA, IPVVA, IPVPA, VVPL, VPKPL, VPSL, IPPA, VIPL, VPAL, VPVVL, VPQ, VPIIL, HAYVFGVEDTLNALESGAIETL WENLDINR or YVFGVEDTLNALESGAIETL IVWENLDINR. The invention further relates to a preparation method of the polypeptide.

This invention discloses the application of chestnut total burdock ethanol extract in the preparation of hypoglycemic drugs. In this invention, the chestnut total burdock ethanol extract with hypoglycemic effect is obtained by reflux extraction of chestnut total burdock with 70% ethanol. This extract can significantly inhibit the activity of α-glucosidase and has a significant inhibitory effect on postprandial blood glucose levels in T2DM model mice, exhibiting a significant hypoglycemic effect in vivo.

The invention discloses a sea cucumber-sourced dual inhibitory peptide with functions of reducing blood pressure and blood sugar and application thereof, and belongs to the technical field of bioactive peptide biology. The novel active peptide with ACE (angiotensin converting enzyme) and DPP-IV (dipeptidyl peptidase-IV) dual inhibitory activity is prepared and identified from sea cucumber viscera enzymatic hydrolysate, can simultaneously inhibit the activity of ACE and DPP-IV, can simultaneously relieve hypertension and type 2 diabetes mellitus, and has application value in preparation of products with effects of reducing blood pressure and blood sugar. The active peptide provided by the invention can simultaneously inhibit the activity of ACE and DPP-IV, has the characteristics of simple structure, safety, strong activity and the like, can play a role in nutrition and health care, is expected to provide effective active raw materials for developing prevention and treatment type functional foods or health care products for reducing blood pressure and blood sugar or reducing blood pressure and blood sugar, and has wide application prospects. Wide application prospects are realized.

The invention provides application of ascorbyl glucoside in health food and oral care products, and belongs to the field of health food and oral care, and the configuration of the ascorbyl glucoside is 2-O-alpha-D-glucosyl-L-ascorbic acid (AA2G). The AA2G can be used for effectively inhibiting the activity of alpha-glucosidase and has a relatively high binding rate to bile acid; animal experiments show that AA2G can significantly reduce the blood sugar concentration, serum triglyceride (TG) concentration and serum total cholesterol (TC) concentration of diabetic model mice, and has the efficacy of assisting in reducing blood sugar and blood fat. In addition, the AA2G also has an inhibiting effect on streptococcus mutans and porphyromonas gingivalis, and has a decayed tooth resisting effect. In addition, the AA2G can continuously and stably exert the effect of assisting in reducing blood sugar, and the long-acting blood sugar reducing capacity of the AA2G is obviously superior to that of VC and beta-configuration ascorbic acid glucoside (AA-2beta G). The AA2G is applied to health-care food and oral care products, and can effectively reduce blood sugar and blood fat and effectively improve the problem of decayed teeth.

The present application provides a traditional Chinese medicine composition with blood sugar lowering efficacy and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines; the traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: birch juice 140-200 parts, jujube fruit 20-40 parts, rehmannia 20-40 parts, adenosma 18-26 parts, periploca 18-26 parts, ophiopogon 18-26 parts, bamboo shavings 12-19 parts, leech 12-19 parts, psyllium 12-19 parts, dogwood 10-14 parts, gordon euryale seed 10-14 parts. In the traditional Chinese medicine composition, the blood sugar lowering effect is mainly achieved by repairing the function of islet beta cells, promoting the regeneration of islet beta cells, improving sugar metabolism, increasing the sensitivity of insulin or improving insulin resistance, so that the overall prescription achieves the effects of invigorating the spleen and lung, nourishing yin and reducing fire, benefiting the stomach and producing saliva, astringing the spleen essence, promoting transportation and transformation, tonifying the kidney and strengthening the body, and relieving polydipsia and restlessness.

The invention provides low-GI coarse cereal and mixed bean brewing powder and a preparation method and application thereof.The preparation method comprises the steps that firstly, tartary buckwheat bran is treated with atmospheric pressure cold plasma, composite cellulose enzymolysis and calcium ion induction gelation are combined, a porous shear thinning gel structure is formed through directional freezing and thawing, and the problem of caking during brewing is solved; secondly, a two-stage fermentation process is adopted, monascus and lactobacillus casei are inoculated in the initial stage, a monascus secretase system is used for breaking cell walls to release sugar, a hypha network is constructed, and embedding of rosa roxburghii tratt pomace polyphenol and synthesis of monacolin K and GABA are synchronously achieved; in the later period, propionibacterium freudenreichii is inoculated to convert lactic acid to generate propionic acid, insulin sensitivity is improved through GABA, and the propionic acid activates GLP-1 to delay gastric emptying, so that the GI value of the product is remarkably reduced. The finally prepared product is fast to brew and disperse and smooth in taste, has the effects of lowering cholesterol and regulating blood sugar, and provides novel healthy food for people with diabetes and metabolic syndromes.

The invention discloses a taste-masked blood sugar-reducing food-medicine homologous homogenized diet and a preparation method thereof, and belongs to the technical field of nutritional products. Comprising the following steps: performing low-temperature ultrasonic elution on food-medicine homologous raw and auxiliary materials with the blood sugar reducing effect by taking water as a solvent, and then filtering; extracting and concentrating to obtain an extract; then adding beta cyclodextrin, and carrying out wet grinding; freeze-drying and crushing the material after the reaction is finished; and mixing with other auxiliary materials to obtain the taste-masked blood sugar-reducing homologous homogenized diet with food and medicine. The traditional Chinese medicine peculiar smell of the homogenized diet with homology of medicine and food can be effectively removed through alkaloid elution and beta-cyclodextrin embedding technologies under a specific process, and a better three-level texture is presented.

The invention discloses a casein source DPP-IV inhibitory peptide as well as a preparation method and application thereof. The casein source DPP-IV inhibition tetrapeptide and the casein source DPP-IV inhibition pentapeptide are MPIQ and MPIQA respectively, the DPP-IV inhibition activity is high, the IC50 value is 78.89-108.82 mu M, and the casein source DPP-IV inhibition tetrapeptide and the casein source DPP-IV inhibition pentapeptide can be prepared through a chemical synthesis method or obtained through biological enzymolysis of casein and can be used for preparing food or medicine with the blood sugar reducing effect. Besides, the casein hydrolysate containing the tetrapeptide MPIQ and the pentapeptide MPIQA is prepared through a biological enzymolysis method, the raw material cost is low, operation is convenient, and the casein hydrolysate also has high DPP-IV inhibitory activity.

The present invention belongs to the field of preparation of health foods, and particularly relates to a composition with a synergistic hypoglycemic effect and a preparation method thereof. The composition contains a plant complex and a black ginger extract. The plant complex is obtained by processing astragalus membranaceus, polygonatum sibiricum, odoratum, cinnamon, etc., and has a significant hypoglycemic effect. The black ginger extract is processed from black ginger and loaded and wrapped in combination with hydroxypropyl methylcellulose, stevioside, etc., and has a high bioavailability. The composition of the present invention has a synergistic hypoglycemic function, can effectively reduce the fasting blood glucose level of patients, and also has the functions of repairing the islets, increasing insulin sensitivity, and improving insulin resistance. The composition is natural in source and high in safety, and can be added as an ingredient to obtain a food with hypoglycemic function, or can be used to make different types of health products such as granules, tablets, capsules, etc.

The present invention discloses bioactive peptides, preparations and applications thereof with antioxidant and hypoglycemic effects, and belongs to the technical field of bioactive peptides. The bioactive peptide of the present invention is shown as at least one of SEQ ID NO: 1 to SEQ ID NO: 4. The present invention uses defatted Xanthoceras sorbifolia meal as raw material, and after high-temperature heat treatment and ultra-high pressure pretreatment, separates bioactive peptides with antioxidant and hypoglycemic effects by enzymatic hydrolysis, ultrafiltration, liquid chromatography separation technology and combined with bioinformatics technology, and preliminarily identifies its components and sequences by liquid chromatography-mass spectrometry technology. And chemical synthesis is carried out according to the identified peptide sequence to obtain 4 bioactive peptides with antioxidant and hypoglycemic effects. After testing, these peptides and their composite peptides all have good α-glucosidase and α-amylase inhibitory activity, and have good application prospects in the preparation of products with antioxidant and hypoglycemic effects.