Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

67 results about "Glycemic efficacy" patented technology

Glycemic efficacy refers to the capacity of regulated glycemic levels to produce an effect in people with diabetes and heart disease. According to Zeev Vlodaver, Robert F. Wilson and Daniel J. Garry, "exenatide and liraglutide are synthetic GLP-1 agonists and have demonstrated glycemic efficacy (HbA1c reductions of between 0.7 and 2%) associated with mild weight loss." Glyburide, metformin and rosiglitazone have been assessed as a monotherapy in the durability of glycemic efficacy.

Traditional Chinese medicine preparation with effect of lowering blood sugar, preparation method and application thereof

The invention discloses a traditional Chinese medicine preparation with the effect of lowering blood sugar, which comprises the following raw materials in parts by weight: 0.5-60 parts of malus hupehensis extract, 1-95 parts of peptide powder and 2-70 parts of oligosaccharide. The preparation method comprises the following steps: (1) preparing the malus hupehensis extract: taking the dry tree leaves of malus hupehensis, taking ethanol as a solvent, refluxing, extracting, concentrating the extract, standing below 1-4 DEG C, centrifugalizing, removing a precipitate and concentrating supernatant liquid for later use; (2) mixing: adding the peptide powder into water, mixing evenly, regulating the sugar degree, heating, then adding the malus hupehensis extract and the oligosaccharide, mixing evenly, sterilizing and drying to obtain fine powder. The traditional Chinese medicine preparation has burnt odor in smell, is sweet and bitter in taste, has obvious curative effect and good effect of lowering sugar when being used as a medicine for lowering the blood sugar, can obviously improve the clinical symptoms of mouth dryness, throat dryness, polydipsia, frequent micturition with large quantity, myasthenia of limbs, dizziness and the like and has the functions of nourishing yin, tonifying the kidney, supplementing qi, promoting the production of the body fluid and the like.
Owner:LINYI SHANSONG BIOLOGICAL PRODS

Blood-glucose-lowering ganoderma lucidum instant micro-encapsulated preparation and preparation method thereof

The invention discloses a blood-glucose-lowering ganoderma lucidum instant micro-encapsulated preparation and a preparation method thereof. The method includes the specific steps of conducting monascus fermentation, water extraction, alcohol extraction, multi-stage micro-encapsulation, spray drying and granulating processes with blood-glucose-lowering ganoderma lucidum sporocarp and conidial powder as raw materials to prepare the blood-glucose-lowering ganoderma lucidum instant micro-encapsulated preparation. The blood-glucose-lowering ganoderma lucidum instant micro-encapsulated preparation prepared through the method brings the medicinal value of monascus and ganoderma lucidum into full play, functional components in blood-glucose-lowering ganoderma lucidum are efficiently enriched, the preparation process is green and mild, industrial production is easy, the obtained product has good water dispersity, storage stability and blood glucose lowering function, the use convenience of the product and the bioavailability in human bodies are effectively improved, guarantees are provided for development, application and consumption of the blood-glucose-lowering ganoderma lucidum product, and the preparation has great significance in promoting the development of the blood-glucose-lowering ganoderma lucidum industry and promoting the national health.
Owner:RIZHAO POLYTECHNIC

Preparation method of sweet potato leaf health tea with effect of lowering blood glucose

InactiveCN105746772ARetain nutrientsSignificant effect of hypoglycemic health carePre-extraction tea treatmentMetabolism disorderBiotechnologyBULK ACTIVE INGREDIENT
The invention provides a preparation method of sweet potato leaf health tea with the effect of lowering blood glucose. The sweet potato leaf health tea has the effects of improving the immunity, lowering the blood sugar, detoxifying, preventing and treating nyctalopia and the like. The preparation method has the advantages that firstly, a core component, namely a sweet potato leaf ethanol extracting solution, is prepared by a degradation process of secondary ultrasonic waves and an alcohol extraction method, and nutritional ingredients of sweet potato leaves are effectively kept; secondly, a core component, namely fermented powder, is prepared through a bacillus aceticus liquid-phase fermentation method, and effective active ingredients of traditional Chinese medicines are extracted to the greatest extent by utilizing the fermentation of bacillus aceticus, so that the health performance of the product is improved; and thirdly, common tea leaves are used as a carrier, and the effective active ingredients of the raw materials are sufficiently absorbed by tea leaves through a normal-temperature fermentation pickling method; and a production process is simple and easy to operate so that the sweet potato leaf health tea is a health beverage suitable for old people, particularly patients with diabetes mellitus, and the health effect of lowering blood glucose is remarkable.
Owner:赵洪军

Method for the preservation of biological activity of activity polypeptides agent which is made from plants and is took orally for reducing blood suger

The present invention provides process of preparing orally taken preparations with blood sugar reducing active polypeptide component extracted from cucurbit plant. The blood sugar reducing active polypeptide component and protein hydrolase inhibitor extracted separately or simultaneously from cucurbit plant are cooled, dried, mixed in certain ratio while adding proper amount of supplementary material, and further treated to produce capsule, tablet, granule or buccal tablet for treating type I and type II diabetes. The blood sugar reducing active polypeptide component is prepared with cucurbit plant material and through crushing, homogenating, extracting, filtering, column chromatography, cooling, drying and other steps.
Owner:ZHEJIANG REACHALL PHARMA

Hypoglycemic composition as well as preparation method and application thereof

The invention belongs to the technical field of hypoglycemic health care products, and particularly relates to a hypoglycemic composition as well as a preparation method and application thereof. The hypoglycemic composition comprises a natural plant component extract, a fungus component extract, and a product of the natural plant component extract subjected to bacterial fermentation, wherein the natural plant component extract is prepared by performing enzymolysis, water extraction and filtering on a natural plant component; the fungus component extract is prepared through alcohol extraction and water extraction. The invention further discloses a preparation method of the hypoglycemic composition. The method comprises the following steps: a1, preparing the natural plant component extract,the fungus component extract, and the product of the natural plant component extract subjected to bacterial fermentation; b1, mixing products in the step a1 according to a ratio of 3:1:1, so as to obtain a product. The composition has good hypoglycemic efficacy and comprehensive nursing effect on bodies.
Owner:广州普罗艾森健康科技有限公司

Astaxanthin health care capsule with blood sugar decreasing effect

The invention discloses an astaxanthin health care capsule with a blood sugar decreasing effect. The astaxanthin health care capsule is manufactured according to compatibility of astaxanthin and Chinese herbal medicine raw materials. The formula including 30 to 40 parts of astaxanthin, 15 parts to 20 parts of bitter gourds, 15 parts to 18 parts of lycium chinense, 10 parts to 14 parts of corn stigma, 8 parts to 10 parts of radix rehmanniae preparata, 8 parts to 10 parts of liquorice, 6 parts to 10 parts of Chinese magnoliavine fruit, 4 parts to 8 parts of atractylodes macrocephala koidz, 5 parts to 8 parts of cortex lycii radicis, 4 parts to 6 parts of platycodon grandiflorum, 4 parts to 6 parts of rhizoma anemarrhenae, 4 parts to 6 parts of smoked plum, 3 parts to 5 parts of smoked plum and 2 parts to 3 parts of stevia rebaudiana is preferentially selected, and the astaxanthin health care capsule is then prepared through the processes of blending, mixing, sterilizing and capsule filling. The astaxanthin health care capsule has the product advantages that the remarkable effects of decreasing blood sugar, tonifying qi, achieving invigoration, supporting the healthy energy, resisting fatigue, prolonging life and the like are achieved through the cooperative effect of astaxanthin and the Chinese herbal medicine, and the astaxanthin health care capsule is safe, free of side effects and convenient to eat and has good market application prospects.
Owner:QINGDAO HAODA MARINE HEALTH FOOD

Mesembryanthemum crystallinum D-pinitol extract with hypoglycemic effect as well as preparation method and application thereof

The invention relates to the technical field of plant extraction, in particular to a mesembryanthemum crystallinum D-terpineol extract with hypoglycemic effect as well as a preparation method and application thereof. The method comprises the following specific steps: material pretreatment, vacuum freezing combined with vacuum microwave drying, material crushing, and extraction of mesembryanthemumcrystallinum D-pinitol by response surface method. According to the method, mesembryanthemum crystallinum is dried through a vacuum freezing and vacuum microwave drying combined technology, then the mesembryanthemum crystallinum D-pinitol is extracted through response surface method, meanwhile, water is taken as an extraction solvent, operation is easy, the price is low, the extraction rate is high, and active ingredients in mesembryanthemum crystallinum can be reserved to the maximum extent. The mesembryanthemum crystallinum D-terpineol extract prepared by the method can significantly reducepostprandial blood glucose and fasting blood glucose of diabetic rats, improve glucose tolerance and repair damaged pancreatic beta cells, and has the effect of improving diabetic syndrome.
Owner:ZHEJIANG ACADEMY OF AGRICULTURE SCIENCES

Traditional Chinese medicine composition with hypoglycemic effect, and preparation method and application thereof

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition with a hypoglycemic effect, and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 300-400 parts of radix astragali, 200-350 parts of rhizoma polygonati, 200-350 parts of radix puerariae lobatae, 200-350 parts of radix et rhizoma salvia miltiorrhiza, 120-250 parts of radix ophiopogonis and 120-250 parts of fiveleaf gynostemma herb. According to the theory of traditional Chinese medicine, the radix astragali, the rhizoma polygonati, the radix puerariae lobatae, the radix et rhizoma salvia miltiorrhiza, the radix ophiopogonis and the fiveleaf gynostemma herb are combined reasonably, and the obtained composition has the significant hypoglycemic effect, has no toxic and side effect and has good market promotion value and medical application value.
Owner:THE SECOND XIANGYA HOSPITAL OF CENT SOUTH UNIV

Health-care yellow wine with blood sugar reducing effect and preparation process thereof

The invention discloses health-care yellow wine with a blood sugar reducing effect and a preparation process thereof, relates to the technical field of health-care food, and aims to solve the problemof reducing the digestion rate of starch. The health-care yellow wine with the blood sugar reducing effect is prepared from the following components in parts by weight: 3.5 parts of quercetin and 3.5parts of cyaniding-3-glucoside. The preparation process of the health-care yellow wine with the blood sugar reducing effect comprises the following step: taking the components of the raw materials forlater use. According to the health-care yellow wine with the blood sugar reducing effect and the preparation process thereof, the quercetin and the cyaniding-3-glucoside are added to inhibit amylolytic enzyme from releasing glucose and interfere with digestion of starch food, so that the digestion rate of the starch can be effectively reduced, and sudden rise of blood sugar is avoided; the two polyphenols interact with the amylolytic enzyme to inhibit the biological activity of the amylolytic enzyme; and when the addition amount is greater than 5%, the hydrolysis degree of the starch can be reduced by 80%, so that generation of sugar in blood is greatly reduced, and the blood sugar concentration is reduced to relieve symptoms of diabetes.
Owner:绍兴玖琔科技有限公司

Composite sea cucumber extract with hypoglycemic activity and preparation method and application thereof

The invention discloses a composite sea cucumber extract with hypoglycemic activity and a preparation method and application thereof. The method comprises the following steps: mixing two types of low-edible-value dry sea cucumbers used as raw materials in a proportion, soaking the sea cucumbers in warm water, performing mincing, adding water for enzymolysis, performing high-temperature acid extraction, performing ultrafiltration to remove impurities, performing graded alcohol precipitation, performing precipitation redissolution, performing reduced-pressure concentration, and finally performing freeze drying to obtain the composite sea cucumber extract with a hypoglycemic effect. The polysaccharide substance content of the extract is greater than 30%, the sulfate group content is greater than 10%, and the extract has a good hypoglycemic effect on the animal level. The extraction technology is simple, the whole technological process can meet the food-grade requirement, and the sea cucumber extract can be applied to the fields of medicines, health care products, food and the like.
Owner:SOUTH CHINA UNIV OF TECH +1

A kind of hypoglycemic composition containing medlar

The invention provides food or a healthcare product or a medicine composition containing barbary wolfberry fruits and reducing blood glucose. The food or the healthcare product or the medicine composition comprises, by weight, 1-10 parts of barbary wolfberry fruits and 10-20 parts of malus hupehensis leaves. The barbary wolfberry fruits are obtained after fresh wolfberry fruits are punched through a puncher and dried. It is found that after the barbary wolfberry fruits and the malus hupehensis leaves are combined for use, the synergistic interaction effect is achieved, hypoglycemic activity is improved, and the effect is superior to that achieved through independent use of the barbary wolfberry fruits and the malus hupehensis leaves through research. It is further found that after the barbary wolfberry fruits and the malus hupehensis leaves are combined at the specific ratio of 5:15, the blood glucose reducing effect is better, and the effect is superior to that achieved through combination of barbary wolfberry fruits and malus hupehensis leaves at other ratios of 1:10 and 10:10 in experiments. Based on the research, the novel composition reducing blood glucose is provided for providing a new choice for clinical medication and healthcare treatment.
Owner:CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST +1

Spinoside, preparation thereof and application of spinoside in preparation of hypoglycemic drugs

ActiveCN113214349AInhibits alpha-glucosidaseInhibits alpha-amylaseOrganic active ingredientsMetabolism disorderSpinosideEthyl acetate
The invention belongs to the field of traditional Chinese medicines, and discloses jujuboside, preparation thereof and application of the jujuboside in preparation of hypoglycemic drugs. The method comprises the following steps: 1) heating, refluxing and extracting spina date seeds by adopting an ethanol water solution to obtain a spina date seed ethanol extract; mixing the spina date seed ethanol extract with water, extracting with petroleum ether, ethyl acetate and n-butyl alcohol, collecting n-butyl alcohol phase extract liquor, concentrating and drying to obtain spina date seed primary saponin; or (2) purifying the spina date seed primary saponin, sequentially carrying out gradient elution by using water and ethanol solutions with different concentrations, and concentrating and drying eluent obtained by eluting by using a 50% ethanol solution to obtain spina date seed secondary saponin. The spina date seed saponin is spina date seed primary saponin and / or spina date seed secondary saponin. The jujuboside is applied to preparation of hypoglycemic drugs. The jujuboside can be used for remarkably inhibiting alpha-glucosidase and alpha-amylase and improving HepG2 cell insulin resistance so as to play a role in reducing blood sugar.
Owner:汉方萃取生物科技(海南)股份有限公司

Preparation method of bitter gourd health-caring food with auxiliary blood-glucose-reducing effect

The invention provides a preparation method of a bitter gourd health-caring food with an auxiliary blood-glucose-reducing effect. The bitter gourd health-caring food with the auxiliary blood-glucose-reducing effect is prepared by rationally compounding an alcohol extract of bitter gourds with a water extract composition of fructus momordicae, mulberry fruits, stigmata maydis and stevia; the bittergourd health-caring food specifically comprises the following ingredients in parts by weight: 60-70 parts of the alcohol extract of the bitter gourds, and 30-40 parts of the water extract compositionof the fructus momordicae, the mulberry fruits, the stigmata maydis and the stevia; and the water extract composition is prepared from the fructus momordicae, the mulberry fruits, the stigmata maydisand the stevia at mass ratio of (30-35) to (20-25) to (5-8) to (5-8). The bitter gourd health-caring food with the auxiliary blood-glucose-reducing effect is capable of significantly reducing fastingblood glucose; compared with the prior art, the bitter gourd health-caring food with the auxiliary blood-glucose-reducing effect has equivalent or better auxiliary blood-glucose-reducing effects, andproduces synergistic effects. In addition, the raw materials all have the characteristics of being rich in resources, wide in distribution, low in cost, easy to obtain and the like; and the production processes are relatively simple and relatively low in operation cost. Thus, the bitter gourd health-caring food with the auxiliary blood-glucose-reducing effect is more suitable for ordinary consumers and high in safety.
Owner:广州汝丽多食品科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products