Detection method and kit for porous dental hydroxyapatite
A hydroxyapatite and kit technology, which can be used in the detection/measurement of irregular teeth, dental preparations, dentistry, etc., can solve the problems of difficult differential diagnosis and poor MIH effect.
Active Publication Date: 2016-07-06
INCISIVE TECH PTY LTD
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- Description
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Problems solved by technology
There are currently no products available for the diagnosis and restoration of MIH or other DDDs, and the differential diagnosis of caries and different types of DDD is difficult and relies heavily on the experience and skill of each dental professional
Procedures and / or products currently developed for caries remineralization do not respond well to MIH
Method used
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Abstract
The invention relates to a kit and a probe for detecting porous tooth hydroxyapatite, including protein or detection substance which can be combined with porous tooth hydroxyapatite. The invention also relates to a method for detecting a condition involving porous dental hydroxyapatite comprising detecting protein bound to porous dental hydroxyapatite in or on the surface of a subject's tooth or tooth sample. The present invention also relates to a method for detecting hypomineralized developmental tooth defect (DDD) or for detecting intact and / or damaged MIH enamel, and to a kit for removing proteins bound to porous dental hydroxyapatite and methods.
Description
technical field The present invention relates to a kit and probe for detecting porous hydroxyapatite in teeth, and a method for detecting conditions involving porous hydroxyapatite in teeth. Background technique The elasticity of teeth depends on a complex interaction between minerals (called hydroxyapatite) and organic components (proteins, cells and tissues). Under normal conditions, hydroxyapatite in enamel and dentin forms an extremely dense structure that provides the hardness and toughness needed to maintain tooth integrity. The loss of mineral density in enamel and dentin leads to abnormally porous hydroxyapatite, which in turn leads to a decrease in tooth physical elasticity and structural damage. Porous hydroxyapatite is caused by several common conditions including dental caries and developmental tooth defects (DDD). Dental caries (tooth decay) is a disease caused by acid-secreting bacteria. Acids produced by cariogenic bacteria dissolve hydroxyapatite in a pr...
Claims
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IPC IPC(8): A61K6/00A61K49/00A61Q11/00
CPCA61K49/001A61K49/0438A61K6/25A61K6/00A61K49/00A61Q11/00C07K14/00G01N33/6893A61B5/4547A61K49/006
Inventor 迈克尔·詹姆斯·哈伯德乔纳森·爱德华·曼格姆
Owner INCISIVE TECH PTY LTD
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