Preparation method of radioactivity lung injury rabbit-step model
A radioactive lung injury and ladder technology, applied in the field of medical models, can solve the problems of poor effect, radiation sensitivity, and high mortality, and achieve the effects of short modeling time, easy replication, and low model mortality.
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[0013] The present invention will be further described below in conjunction with specific examples.
[0014] A preparation method of a rabbit ladder model of radiation-induced lung injury comprises the following steps:
[0015] New Zealand white rabbits, regardless of sex, aged 1.0-1.2 years, and weighing 2.0-3.0 kg, were randomly divided into an experimental group and a control group with the same total number of groups and the same number of rabbits in each group; the experimental group and the control group were both After intramuscular injection of anesthesia, CT scanning of the whole lung is performed first, and then the target area is delineated, and then the radiotherapy three-dimensional plan (TPS, CMS Xio type) for unilateral lung irradiation field design and dose calculation is performed. Both the lower and contralateral thorax were covered with lead blocks; the experimental group was irradiated by a linear accelerator (SIEMENS Primus M), with the front and rear faci...
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