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34 results about "Radiation-induced lung injury" patented technology

Radiation-induced lung injury is a general term for damage to the lungs which occurs as a result of exposure to ionizing radiation. In general terms, such damage is divided into early inflammatory damage (radiation pneumonitis) and later complications of chronic scarring (radiation fibrosis). Pulmonary radiation injury most commonly occurs as a result of radiation therapy administered to treat cancer.

Accurate detection and assessment of radiation induced lung injury based on a computational model and computed tomography imaging

A system and computation method is disclosed that identifies radiation-induced lung injury after radiation therapy using 4D computed tomography (CT) scans. After deformable image registration, the method segments lung fields, extracts functional and textural features, and classifies lung tissues. The deformable registration locally aligns consecutive phases of the respiratory cycle using gradient descent minimization of the conventional dissimilarity metric. Then an adaptive shape prior, a first-order intensity model, and a second-order lung tissues homogeneity descriptor are integrated to segment the lung fields. In addition to common lung functionality features, such as ventilation and elasticity, specific regional textural features are estimated by modeling the segmented images as samples of a novel 7th-order contrast-offset-invariant Markov-Gibbs random field (MGRF). Finally, a tissue classifier is applied to distinguish between the injured and normal lung tissues.
Owner:UNIV OF LOUISVILLE RES FOUND INC

Application of kaempferol in preparation of medicines for preventing and treating radiation-induced pulmonary injury

The invention discloses application of kaempferol in preparation of medicines for preventing and treating radiation-induced pulmonary injury. The experiment proves that kaempferol can obviously improve inflammatory exudation of lung tissues suffering from the mouse radiation-induced pulmonary injury and has an excellent positive effect on the radiation-induced pulmonary injury. The invention provides a novel drug for radiation-induced pulmonary injury diseases. A novel thought is provided for research and development of medicines for treating the radiation-induced pulmonary injury, and the application path of kaempferol in the field of medicines is widened.
Owner:SHANDONG RES INST OF TUMOUR PREVENTION TREATMENT

Therapy for radiation-induced lung injury

Methods are disclosed for therapy of radiation-induced lung injury and other lung diseases using R-spondin1.
Owner:ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIV

Application of mesenchymal stem cell exosome to preparation of medicament for preventing and treating radiation-induced lung injury (RILI)

The invention discloses application of a mesenchymal stem cell exosome to preparation of a medicament for preventing and treating radiation-induced lung injury (RILI). After a radiated mouse with lunginjury is treated by adopting tail vein injection administration of the mesenchymal stem cell exosome, inflammatory factor level is effectively lowered (IL-1beta, IL-6, TNF-alpha, TGF-beta); the survival rate of the mouse is improved effectively; and pneumonia and lung fibrosis lesion caused by the RILI are reduced. The mesenchymal stem cell exosome has the advantages of high security, stable chemical property and easiness in storage, and a new way is provided for safely and effectively treating the RILI.
Owner:中科广聚(北京)生物医学技术中心有限公司 +1

Application of geniposide

ActiveCN102908356AImprove immunityMitigate radiation-induced lung injuryOrganic active ingredientsRespiratory disorderThoracic cancerRadiochemistry
The invention discloses an application of geniposide in preparation of medicines for treating and preventing a radioactive lung injury caused by ionizing radiations. The geniposide as the medicines for treating and preventing the radioactive lung injury caused by aerospace, nuclear radiation and thoracic cancer radiotherapy strengthens the immunity of the organism to alleviate the radiation injury, so that the geniposide can provide a selective radiation protection idea for the radioactive lung injury caused by ionizing radiations, including an aerospace business, a nucleus scientific and technological development and a breast cancer radiotherapy and the like.
Owner:INST OF MODERN PHYSICS CHINESE ACADEMY OF SCI

Application of traditional Chinese medicine composition in preparing medicine for treating radiation-induced pulmonary injury

The invention discloses an application of a traditional Chinese medicine composition in preparing a medicine for treating radiation-induced pulmonary injury. The traditional Chinese medicine composition is mainly composed of fructus forsythiae, honeysuckle flowers, isatis root, rheum officinale, pogostemon cablin, rhizoma dryopteris crassirhizomae and rhodiola rosea, has the integral regulation advantages of compound traditional Chinese medicines, can eliminate pathogenic factors, relieve the symptoms, and adjust immunity, and has a remarkable curative effect for treating radiation-induced pulmonary injury proved by the clinical test.
Owner:BEIJING YILING PHARMA

Traditional Chinese medicinal composition for treating radiation-induced lung injury

The invention discloses a traditional Chinese medicinal composition for treating radiation-induced lung injury. In traditional Chinese medicine, the radiation-induced lung injury belongs to 'consumptive lung disease' and 'gasp syndrome', and is caused by invasion of heat toxin, damage of collaterals in lung, intermingled phlegm and blood stasis, impairment of fluid and qi, and qi and yin injury. The traditional Chinese medicinal composition is prepared from the following traditional Chinese medicines capable of nourishing yin and clearing away heat, and moistening lung to arrest cough: rhizoma tupistrae chinensis, tendrilleaf solomonseal rhizome, unpleasant swallowwort herb, mountain oreas herb, brooklet anemone root, botrychiam ternatum, narrow-leaved lindernia, pleurotus albellus, paraphlonia, affine cudweed, laminated sanicle herb and mulberry leaf. The traditional Chinese medicinal composition is prepared into a decoction; a clinical test shows that total effective rate of the traditional Chinese medicinal composition is 97.1%, which is obviously excellent than that of a control group; the traditional Chinese medicinal composition is low in side effect.
Owner:冯庆亮

Application of quercetin in drug for preventing and treating acute radiation pneumonitis and preparation prepared from quercetin

InactiveCN103251583AImprove inflammatory exudationOrganic active ingredientsPill deliveryPulmonary InjuryPharmaceutical drug
The invention discloses application of quercetin in a drug for preventing and treating acute radiation pneumonitis and a preparation prepared from the quercetin. The quercetin can be used for remarkably improving inflammatory exudation of mice radiation-induced pulmonary injury lung tissue, has a certain preventing and treating effect for the radiation-induced pulmonary injury, so that a novel material drug is provided for treating the acute radiation pneumonitis.
Owner:李宝生

Preparation method of radioactivity lung injury rabbit-step model

InactiveCN103100144AReduce mortalitySimple modeling operationRadiation therapyPulmonary InjuryX-ray
The invention relates to a preparation method of a radioactivity lung injury rabbit-step model. The preparation method of the radioactivity lung injury rabbit-step model is characterized in that anesthesia is carried out through intramuscular injection, and then a single full lung field gray high-energy x ray is used for radiating after fixing is achieved. In addition, a control group which is healthy and not radiated is established, observation research is carried out in different time points after radiation, and finally a radioactivity lung injury rabbit-step model is successfully established after being verified by results of blood serum, pathology, an electron microscope, high-resolution computed tomography (CT), CT perfusion weighted imaging and the like. An animal model established by the preparation method can well simulate happening and developing regular patterns and characteristics of human radioactivity lung injury, and has the advantages of being simple in model manufacturing operation, low in model manufacturing cost, short in model completing time, low in model dead rate, easy to duplicate, good in controllability, good in imaging effect and the like, beneficially for radioactivity lung injury experiment study and medical development and study such as relevant follow-up treatment, curative effect evaluation, and has scale popularization and application value.
Owner:胡晓云

Application of ghrelin in prevention or/and treatment of radiation-induced lung injury

The invention provides a novel medicinal application of ghrelin, namely application of ghrelin in prevention or / and treatment of radiation-induced lung injury, radiation-induced pneumonia and late pulmonary fibrosis. In-vivo experiments verify that the ghrelin is effective in the fields of prevention or / and treatment of radiation-induced lung injury, radiation-induced pneumonia and late pulmonary fibrosis. According to the novel medicinal application of the ghrelin, the ghrelin is creatively applied to prevention or / and treatment of radiation-induced lung injury, radiation-induced pneumonia and late pulmonary fibrosis, and a novel choice is provided to clinical treatment.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Application of amlexanox in the preparation of drugs for the prevention and treatment of ionizing radiation-induced radioactive lung injury

The invention relates to the field of new medical uses, and particularly relates to an application of amlexanox in the preparation of drugs for the prevention and treatment of ionizing radiation-induced radioactive lung injury. The structure formula of the amlexanox is as follows. According to the invention, the provided amlexanox for the preparation of drugs for the prevention and treatment of ionizing radiation-induced radioactive lung injury: is small in toxic and side effects, and is widely used in the clinical treatment of recurrent oral ulcer, asthma, allergic rhinitis, etc.; and the amlexanox is remarkable in curative effect, and can significantly inhibit radiation-induced lung injury when given at a dose of 50 mg / kg / day three days before irradiation. It shows that the amlexanox isunique in the prevention and protection of ionizing radiation-induced radioactive lung injury, and has broad application prospects in the medical domain in China.
Owner:SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY

Application of bone marrow mesenchymal stem cell to prevention of radiation-induced lung injury

An embodiment of the invention provides application of a bone marrow mesenchymal stem cell to prevention of radiation-induced lung injury. The application of the bone marrow mesenchymal stem cell to prevention of the radiation-induced lung injury is the use of the bone marrow mesenchymal stem cell for prevention of radiation pneumonitis and advanced fibrosis and the improvement of the survival rate of the radiation-induced lung injury. Through experiments, the effectiveness of the bone marrow mesenchymal stem cell in preventing radiation-induced lung injury, including radiation pneumonitis andadvanced fibrosis, is verified. The new medical use of the bone marrow mesenchymal stem cell is developed, the bone marrow mesenchymal stem cell is applied to preventing radiation-induced lung injury, including radiation pneumonitis and advanced pulmonary fibrosis, in a groundbreaking way, and a new choice is provided for clinical treatment.
Owner:中科广聚(北京)生物医学技术中心有限公司 +1

Application of heme oxygenase-1 in diagnosis and treatment of radiation-induced lung injury

The invention belongs to the field of molecular biological diagnosis and treatment of radiation-induced lung injury, and particularly relates to application of heme oxygenase-1 in diagnosis and treatment of radiation-induced lung injury. It is found that serious radiation-induced lung injury is caused by insufficient HO-1 content, so that for a patient subjected to large-dose X-ray radiation therapy, if HO-1 in blood is reduced, radiation-induced lung injury is caused. A drug such as Hemin for enhancing the expression and function of HO-1 can be used as a new method for treating radiation-induced lung injury.
Owner:NANJING MEDICAL UNIV

Chinese herbal compound particle for treating radiation-induced lung injury and preparation method thereof

PendingCN109893613ARetain efficacyDelay the course of the diseaseUnknown materialsGranular deliveryFlosTreatment effect
The invention discloses a Chinese herbal compound particle for treating radiation-induced lung injury. The Chinese herbal compound particle is prepared from the raw materials in parts by weight: 'monarch' medicines, namely 5-8 parts of folium mori, and 5-8 parts of semen armeniacae amarae; 'minister' medicines, namely 3-5 parts of flos lonicerae, 3-5 parts of fructus forsythia, 3-5 parts of herbalophatheri, 4-7 parts of rhizoma coptidis, 8-10 parts of cornu bubali, 5-8 parts of radix dcrophulariae, 5-8 parts of dried radix rehmanniae, 5-8 parts of radix ophiopogonis, 5-8 parts of radix glehniae, and 5-8 parts of radix codonopsis; assistant medicines, namely 4-7 parts of radix salviae miltiorrhizae, 5-8 parts of radix angelicae sinensis, and 4-7 parts of cortex mori; and a guide medicine,namely 3-5 parts of radix glycyrrhizae. The Chinese herbal compound components are reasonable in compatibility, based on 'monarch', 'minister', assistant and guide principles, the multiple medicinal materials are mutually contained and coordinated, taking is convenient, and the Chinese herbal compound particle has a significant treating effect on treatment of radiation-induced lung injury.
Owner:成都市第三人民医院

Uses of Ferroptosis Inhibitors

The invention relates to the technical field of medical science, in particular to new application of a ferroptosis inhibitor. The ferroptosis inhibitor is prepared from Liproxstatin-1, Ferrostatin-1,rosiglitazone, pioglitazone, troglitazone and Zileuton. The new application refers to that the inhibitor is applied to treating radiation-induced pulmonary injury diseases. The application has the advantages that (1) radioactive rays trigger radiation-induced pulmonary injury by mediating pulmonary alveoli epithelial cells to have ferroptosis, the ferroptosis specificity inhibitor can be used to prevent and treat radiation-induced pulmonary injury, and has the important meaning on development of new drug for preventing and treating radiation-induced pulmonary injury; and (2) it is found that radioactive rays can cause cell death through the mode of ferroptosis, and application of the ferroptosis inhibitor also has the significant theoretical meaning on guiding research for guiding radioactive rays to treat cancer mechanism.
Owner:JINSHAN HOSPITAL FUDAN UNIV

Traditional Chinese medicine preparation for preventing and treating yin deficiency and lung heat radiation-induced lung injury and preparation method of traditional Chinese medicine preparation

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation for preventing and treating yin deficiency and lung heat radiation-induced lung injury. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 30-90 parts of radix glehniae, 30-90 parts of fleshly scale leaf of lily, 15-45 parts of the root bark of white mulberry, 30-90 parts of rhizome of paris polyphylla, 10-30 parts of bulbus fritilariae, 15-45 parts of earthworm, 10-30 parts of herbaceous stem of ephedra, 15-45 parts of root-bark of tree peony, 10-30 parts of platycodon, 10-30 parts of semen armeniacae amarae, 10-30 parts of rhizoma anemarrhenae, 15-45 parts of holly leaves, 30-90 parts of rhizoma phragmitis, 15-45 parts of snake gourd fruits and 10-30 parts of liquorice root. The traditional Chinese medicine preparation is reasonable in design, avoids the effect of venous drugs and resulting side effects on the body of a patient, also avoids limitation caused by indication mastery, and overcomes the shortcomings of limitation of methods such as oral preparation of the traditional Chinese medicines to clinical observation and empirical antibiotics treatment.
Owner:SHANXI PROVINCE CHINESE MEDICINE RES INST

Biomarkers and methods of use for radiation-induced lung injury

The present disclosure is directed to methods (e.g., in vitro methods) for use of nicotinamide phosphoribosyltransferase (NAMPT) as a biomarker in radiation-induced lung injury (RILI). Provided herein is an in vitro method for the diagnosis, prognosis, and / or monitoring of RILI in a human subject by providing a tissue or plasma sample from the subject and detecting the level of NAMPT therein, wherein a higher level of NAMPT in the tissue or plasma sample from the subject compared to a healthy control or a reference value is indicative for the presence of RILI in the subject. Further provided herein is a method of detecting NAMPT in a human subject by obtaining a biological sample from the subject, detecting the presence of NAMPT in the sample by contacting the sample with a capture agent that specifically binds NAMPT, and detecting binding between NAMPT and the capture agent.
Owner:THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIV OF ARIZONA

Medicine for preventing and treating acute radiation pneumonitis

The invention discloses a medicine for preventing and treating acute radiation pneumonitis; the effective component of the medicine is procyanidine. The medicine is a procyanidine solution with the concentration of 2.5-3.75mg / ml; the procyanidine solution comprises procyanidine with the purity of 95-99% and a sterile saline solution; the delivery manner of the medicine is aerosol inhalation. The medicine disclosed by the invention has a good prevention and treatment effect to acute radiation pneumonitis and is a plant raw material medicine with a prospect, namely, the procyanidine can be used for preventing and treating acute radiation pneumonitis. Aerosol inhalation of procyanidine can effectively implement targeted drug delivery of lung, and further can avoid the first pass effect, reduce the use level of the medicine and alleviate or avoid adverse drug reactions while directly reaching the site of action, so that the purpose of preventing or even treating acute radiation pneumonitis is achieved.
Owner:张维芬

Protection method for radiation-induced lung injury

PendingCN113768940ASafe and efficient preventionSafe and efficient treatmentOrganic active ingredientsAntinoxious agentsPulmonary InjuryLung tissue
The invention belongs to the technical field of radiation protection and relates to a protection method for radiation-induced lung injury. The protection method comprises the following steps: injecting amifostine into an organism before irradiation, and controlling a body temperature of the organism within a mild hypothermia range after irradiation. By means of the protection method for the radiation-induced lung injury, disclosed by the invention, the injury degree of lung tissue of the organism after irradiation can be safely and efficiently reduced; and when the amifostine injection before irradiation is combined with the application of controlling the body temperature within the mild hypothermia range after irradiation to prepare a medicament for preventing and / or treating the radiation-induced lung injury, the radiation-induced lung injury can be safely and efficiently prevented and / or treated.
Owner:CHINA INST FOR RADIATION PROTECTION

Application of TLR4 excited exosome or exosome preparation in preparation of medicine for preventing and treating radiation-induced lung injury

PendingCN114796273AReduce damageReduced proliferative activityOrganic active ingredientsAntinoxious agentsTissue toxicityPulmonary Injury
The invention relates to application of a TLR4 excited exosome or an exosome preparation in preparation of a medicine for preventing and treating radiation-induced lung injury, and belongs to the technical field of medicines. The invention provides an application of a TLR4 excited exosome or an exosome preparation in preparation of a medicine for preventing and treating radiation-induced lung injury, the TLR4 excited exosome or the exosome preparation is generated after macrophage TLR4 is activated by an agonist, belongs to exosomes generated by a human body, and has no tissue toxicity. Tests prove that the TLR4-excited exosome or the exosome preparation can remarkably relieve the reduction of the proliferation activity of radiation-induced pulmonary epithelial cells and reduce the apoptosis of the pulmonary epithelial cells and the damage degree of DNA after radiation, which shows that the TLR4-excited exosome or the exosome preparation has the uniqueness in the protection of ionizing radiation-induced pulmonary injury, and the TLR4-excited exosome or the exosome preparation can be used for treating the radiation-induced pulmonary injury caused by ionizing radiation-induced pulmonary injury caused by the ionizing radiation-induced pulmonary injury caused by the ionizing radiation-induced pulmonary injury caused by the ionizing radiation-induced pulmonary injury. The clinical application value is extremely high.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL

Application of excited GSTP1 gene in medicine for preventing radioactive lung injury

PendingCN112891547AAvoid damageRaising Radiation Lung InjuryAntinoxious agentsRespiratory disorderCell damageNormal lung
The invention relates to the field of gene medicines, and particularly relates to application of an excited GSTP1 gene in a medicine for preventing radioactive lung injury. Firstly, GSTP1 over-expression plasmids are verified to be capable of remarkably enhancing GSTP1 protein in human normal lung epithelial cells. Furthermore, an MTT experiment is used for finding that over-expression GSTP1 has no influence on cell proliferation, and under radiation pressure, the cell proliferation activity of an over-expression group is higher than that of a no-load plasmid transfection group. Finally, a Westernblot experiment is used for obtaining enhanced GSTP1 gene expression, the occurrence of a cell EMT process caused by radiation is inhibited, and cell injury caused by radiation is weakened. The invention provides the GSTP1 gene and novel application of a reagent for enhancing GSTP1 gene expression. By enhancing GSTP1 gene expression, the injury of radiotherapy to normal lung tissue can be weakened, and therefore the radioactive lung injury caused by ionizing radiation can be effectively prevented.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL

Application of cilengitide in preparation of drugs for preventing radioactive lung injury

PendingCN111135286AIncreased overall survival timeImprove convenienceCyclic peptide ingredientsRespiratory disorderSide effectCilengitide
The invention discloses an application of cilengitide in preparation of drugs for preventing radioactive lung injury. The cilengitide can obviously improve the fibrosis degree and health status of lung tissue after irradiation; total survival time can be prolonged, and lethal side effects are not observed; and the cilengitide has good safety.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

Medicine for treating radiation-induced lung injury and preparation method thereof

The invention discloses a medicine for treating the radiation-induced pulmonary injury and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The medicine comprises the following raw materials constituting effective ingredients: hypoestes purpurea, arrowroot, siegesbeckia orientalis, crepis phoenix, dendrobium jenkinsii wall, ardisia japonica, Chinese alpine rush, wedelia chinensis, tangerine leaf, silverleaf cinquefoil root, pecan, gecko, wood betony, thesium chinense, trichosanthes kirilowii maxim and Chinese squill. The medicine is suitable in compatibility of selected medicines, conforms to the theory of traditional Chinese medicine and pharmacy and modern medicine and pharmacology, has the effects of nourishing yin, engendering fluid, moisturizing lung and relieving cough, activating blood and dissolving stasis and relieving swelling and pain, has an obvious treating effect on treatment of the radiation-induced pulmonary injury, and short in treatment course, allows fast effect, does not relapse after healing, has no toxic and side effects, is low in cost, can achieve the purpose of treating both symptoms and root causes in cost, and has special effect and practicability, thus being worthy of wide popularization and application in clinic.
Owner:赵凌

Application of Glibenclamide in Preparation of Drugs for Protecting Radiation-induced Lung Injury

The invention relates to the technical field of medicines, and provides an application of glibenclamide or derivatives thereof in preparing medicines for preventing and protecting radiation-induced pulmonary injury. Furthermore, the invention also provides a pharmaceutical composition for preventing and protecting the radiation-induced pulmonary injury, wherein the pharmaceutical composition consists of the glibenclamide or derivatives thereof and pharmaceutically acceptable adjuvants. Based upon mice in-vivo experiments, the glibenclamide can obviously relieve a damage degree of blood vessel endothelium caused by radiation, so that increase in erythrocyte effusion is inhibited and the circumstance of pulmonary hemorrhage after the radiation is relieved; and through in-vivo cytological experiments, the glibenclamide can reduce an apoptosis rate of cells which accept the radiation and improve the circumstance of proliferation inhibition, showing that the glibenclamide, when applied in previous ways, can relieve the radiation-induced pulmonary injury of mice and reduce sensitivity of vascular endothelial cells to radiation; therefore, a new evidence is provided for prevention and protection of the radiation-induced pulmonary injury by virtue of the glibenclamide or derivatives thereof.
Owner:SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY

A traditional Chinese medicine composition for treating radiation-induced lung injury

The invention discloses a traditional Chinese medicinal composition for treating radiation-induced lung injury. In traditional Chinese medicine, the radiation-induced lung injury belongs to 'consumptive lung disease' and 'gasp syndrome', and is caused by invasion of heat toxin, damage of collaterals in lung, intermingled phlegm and blood stasis, impairment of fluid and qi, and qi and yin injury. The traditional Chinese medicinal composition is prepared from the following traditional Chinese medicines capable of nourishing yin and clearing away heat, and moistening lung to arrest cough: rhizoma tupistrae chinensis, tendrilleaf solomonseal rhizome, unpleasant swallowwort herb, mountain oreas herb, brooklet anemone root, botrychiam ternatum, narrow-leaved lindernia, pleurotus albellus, paraphlonia, affine cudweed, laminated sanicle herb and mulberry leaf. The traditional Chinese medicinal composition is prepared into a decoction; a clinical test shows that total effective rate of the traditional Chinese medicinal composition is 97.1%, which is obviously excellent than that of a control group; the traditional Chinese medicinal composition is low in side effect.
Owner:冯庆亮

Traditional Chinese medicine composition for treating radioactive injury and preparation method thereof

The invention relates to a traditional Chinese medicine composition for treating radioactive injury and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following 15 raw medicinal materials: radix rehmanniae recen, radix ophiopogonis, radix scrophulariae, codonopsis pilosula, scutellaria baicalensis, thunberg fritillary bulb, blackberry lily, pinellia ternate, white paeony root, salvia miltiorrhiza, moutan bark, mangnolia officinalis, poria cocos, mint and coptis chinensis. The composition in the invention is mild in medicine property, precise and appropriate in compatibility and synergistic in effect, has the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, nourishing lung and kidney and replenishing qi to invigorate the spleen, and is suitable for diseases such as mouth dryness, pharyngalgia, toothache, dry cough and chronic rhinitis caused by acute and chronic radioactive injuries and radiotherapy. Pharmacodynamic tests show that the composition disclosed by the invention has an exact treatment effect on radiation-induced lung injury and radiation-induced intestine injury.
Owner:THE AFFILIATED HOSPITAL OF QINGDAO UNIV

Traditional Chinese medicine preparation for preventing and treating radiation-induced lung injury caused by yin deficiency and lung heat and its preparation method

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation for preventing and treating yin deficiency and lung heat radiation-induced lung injury. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 30-90 parts of radix glehniae, 30-90 parts of fleshly scale leaf of lily, 15-45 parts of the root bark of white mulberry, 30-90 parts of rhizome of paris polyphylla, 10-30 parts of bulbus fritilariae, 15-45 parts of earthworm, 10-30 parts of herbaceous stem of ephedra, 15-45 parts of root-bark of tree peony, 10-30 parts of platycodon, 10-30 parts of semen armeniacae amarae, 10-30 parts of rhizoma anemarrhenae, 15-45 parts of holly leaves, 30-90 parts of rhizoma phragmitis, 15-45 parts of snake gourd fruits and 10-30 parts of liquorice root. The traditional Chinese medicine preparation is reasonable in design, avoids the effect of venous drugs and resulting side effects on the body of a patient, also avoids limitation caused by indication mastery, and overcomes the shortcomings of limitation of methods such as oral preparation of the traditional Chinese medicines to clinical observation and empirical antibiotics treatment.
Owner:SHANXI PROVINCE CHINESE MEDICINE RES INST

Traditional Chinese medicine composition for treating radiation-induced lung injury

The invention relates to a traditional Chinese medicine composition for treating radiation-induced lung injury. The traditional Chinese medicine composition comprises, by weight, 3-7 parts of Melastoma sanguineum, 5-12 parts of caulis mahoniae, 5-10 parts of Ipomoea cairica, 7-12 parts of Begonia evansiania root, 3-5 parts of Disporum calcaratum D. Don, Ainsliaea henvyi Diels, cushaw stem, 10-15 parts of chorion ovi, 3-5 parts of nervilia fordii, 5-8 parts of lemon leaf, 10-15 parts of white inner peel of orange, 3-10 parts of hyacinth bean coat, 3-5 parts of Bulbophyllum radiatum Lindl., 5-10 parts of radix stemonae, 10-15 parts of Trichosanthes kirilowii Maxim, 3-7 parts of Flemingia fruticulosa Wall.ex Coll. and 5-8 parts of Adenophora trachelioides Maxim.. The traditional Chinese medicine composition has effects of cooling and activating blood, clearing away heat and toxic materials, moistening the lung and eliminating dryness, nourishing yin and lowering fire, dispersing blood stasis and dredging collaterals and strengthening the spleen and the stomach and is evident in curative effect on the radiation-induced lung injury, quick in action, safe and free of toxic and side effect.
Owner:陈培才
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