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Traditional Chinese medicine composition for treating gynecologic inflammation and preparation method thereof

A technology of gynecological inflammation and composition, which is applied in the field of traditional Chinese medicine composition for treating gynecological inflammation and its preparation, which can solve the problems of low extraction rate, failure to extract active ingredients, and affect drug efficacy, and achieve excellent results

Active Publication Date: 2013-05-22
GUANGXI WUZHOU PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Due to the different properties of the active ingredients in the nine traditional Chinese medicines, if the above two patents or patent applications use the water extraction method, some active ingredients cannot be extracted, or the extraction rate is low, which will affect the efficacy of the drug.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: the Chinese medicinal composition for the treatment of gynecological inflammation

[0035] 1. Raw materials: 7.69kg of bitter scrophulariae, 11.54kg of gall grass, 7.69kg of angelica, 11.54kg of Caulis Spatholobus, 11.54kg of double-faced needle, 11.54kg of horizontal sutra mat, 11.54kg of persimmon leaves, 11.54kg of scorpion, 15.38 of five-fingered peach kg.

[0036] 2. Preparation method:

[0037] Weigh the ingredients according to the ratio, extract the nine traditional Chinese medicines with ethanol twice, each time add 70% ethanol that is 8 times the total weight of the nine traditional Chinese medicines, and the extraction time is 3 hours each time, combine the extracts, filter, and concentrate the filtrate The clear ointment with a relative density of 1.12 at 60°C was dried into a dry ointment powder to obtain 13.6kg of the traditional Chinese medicine composition (yield 13.6%).

Embodiment 2

[0038] Embodiment 2: the Chinese medicinal composition for the treatment of gynecological inflammation

[0039] 1. Raw materials: 7.69kg of bitter scrophulariae, 11.54kg of gall grass, 7.69kg of angelica, 11.54kg of Caulis Spatholobus, 11.54kg of double-faced needle, 11.54kg of horizontal sutra mat, 11.54kg of persimmon leaves, 11.54kg of scorpion, 15.38 of five-fingered peach kg.

[0040] 2. Preparation method:

[0041] Weigh each component according to the proportioning ratio, extract 2 times of Jiuwei Chinese medicine with ethanol, add 6 times of the total weight of Jiuwei Chinese medicine 30% ethanol each time, each extraction time is 5 hours, combine the extracts, filter, and concentrate the filtrate to The clear ointment with a relative density of 1.20 at 50°C was dried into a dry ointment powder to obtain 15.9kg of the traditional Chinese medicine composition (yield 15.9%).

Embodiment 3

[0042] Embodiment 3: the Chinese medicinal composition for the treatment of gynecological inflammation

[0043] 1. Raw materials: 7.69kg of bitter scrophulariae, 11.54kg of gall grass, 7.69kg of angelica, 11.54kg of Caulis Spatholobus, 11.54kg of double-faced needle, 11.54kg of horizontal sutra mat, 11.54kg of persimmon leaves, 11.54kg of scorpion, 15.38 of five-fingered peach kg.

[0044] 2. Preparation method:

[0045] Take each composition according to proportioning, extract nine flavors of traditional Chinese medicine with ethanol 3 times, add 12 times of the total weight of nine flavors of traditional Chinese medicine 50% ethanol each time, each extraction time is 2 hours, combine extracts, filter, and the filtrate is concentrated to The clear ointment with a relative density of 1.10 at 70°C was dried into dry ointment powder to obtain 14.8kg of the traditional Chinese medicine composition (yield 14.8%).

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Abstract

The invention relates to a traditional Chinese medicine composition for treating gynecologic inflammation and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 7.69 parts of picria fel-terrae, 11.54 parts of herba elephantopi, 7.69 parts of angelica, 11.54 parts of spatholobus stem, 11.54 parts of radix zanthoxyli, 11.54 parts of membranaceous beautyleaf root, 11.54 parts of persimmon leaf, 11.54 parts of Thlaspi arvense and 15.38 parts of radix fici simplicissimae. The traditional Chinese medicine composition is prepared through the following step: performing alcohol extraction on the nine traditional Chinese medicines. By placing a foreign matter in the womb, a rat endometritis model is prepared to verify the effect of the traditional Chinese medicine composition provided by the invention; and experimental results show that the traditional Chinese medicine composition provided by the invention can treat various gynecologic inflammation diseases, especially endometritis, and the treatment effect is superior to the prior art.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating gynecological diseases, in particular to a traditional Chinese medicine composition for treating gynecological inflammation and a preparation method thereof. Background technique [0002] Traditional Chinese medicine believes that the pathogenesis of gynecology can be summarized as visceral dysfunction (mainly spleen deficiency, kidney deficiency, and liver depression), Qi and blood imbalance, and three aspects of Chong, Ren, Du, and belt injuries. Due to the special physiological characteristics of women, such as menstruation, pregnancy, and childbirth, it is easy to cause the emptiness of the blood vessels, and the evil poison takes advantage of the deficiency to invade inward, and the dampness, heat and poison accumulate in the lower jiao, and enter the cells, competing with qi and blood, resulting in gynecological diseases. Various disease diseases. Conflict between g...

Claims

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Application Information

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IPC IPC(8): A61K36/808A61P15/00
Inventor 刘冠萍张栩颜梁云飞贤明华
Owner GUANGXI WUZHOU PHARMA GRP
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