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Traditional Chinese medicinal preparation for treating glaucoma and preparation method thereof

A traditional Chinese medicine preparation, glaucoma technology, applied in the field of pharmacy, can solve the problem of not solving the "cause", not completely changing the eye microcirculation, recurrence and other problems, achieving the effect of convenient administration, prevention and treatment of optic nerve damage, and good curative effect

Inactive Publication Date: 2014-08-06
刘召英
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the surgical treatment only stays in the treatment of the "symptom", does not solve the "cause" problem, and does not completely change the eye microcirculation, so there is still the possibility of recurrence

Method used

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  • Traditional Chinese medicinal preparation for treating glaucoma and preparation method thereof
  • Traditional Chinese medicinal preparation for treating glaucoma and preparation method thereof

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Effect test

preparation example Construction

[0049] When the dosage form of the Chinese medicine is a powder, its preparation method may further comprise the steps:

[0050] In the first step, Xanthium cocklebur, Grasswood fir, Chongshi, Ligustrum lucidum and ginger are mixed according to the stated ratio, and dissolved in ethanol with an alcohol concentration of 80% to 85% relative to the mass of the obtained mixture, 3 to 5 times, Heat and reflux for 2 to 4 hours to extract, filter to obtain the first filtrate; dissolve the filter residue again with ethanol with an alcohol concentration of 85% to 90% relative to the mass of the obtained mixture, and heat and reflux for 1 to 3 hours to extract , filter to obtain the second filtrate; combine the first filtrate and the second filtrate, reclaim ethanol under reduced pressure and concentrate until the concentration of the medicinal solution is 0.8-1.0 g crude drug / mL, and wash through a macroporous adsorption resin column with a volume of 5 L. For deionization, first elute ...

Embodiment 1

[0059] The powder prepared by embodiment 1 the present invention

[0060] Take 70g cocklebur, 150g cassava, 140g chrysanthemum, 160g privet fruit, 240g turnip, 50g aloe vera, 60g cork bark, 70g toosendan, 50g gardenia, 80g safflower, 180g white chrysanthemum, 120g licorice, wolfberry 170g, yam 140g and ginger 190g.

[0061] Its preparation method comprises the following steps:

[0062] In the first step, mix cocklebur, cypress, chrysanthemum, privet and ginger in proportion, dissolve them in ethanol with an alcohol concentration of 80% that is 5 times the mass of the obtained mixture, heat and reflux for 4 hours to extract, and filter , to obtain the first filtrate; the filter residue was dissolved again with 90% ethanol with an alcohol concentration of 3 times relative to the obtained mixture quality, heated and refluxed for 2 hours to extract, filtered to obtain the second filtrate; the first filtrate and the second filtrate were combined 2. Filtrate, reclaim ethanol under...

Embodiment 2

[0066] The tablet that embodiment 2 present invention prepares

[0067] Take 50g cocklebur, 120g cassava, 130g chrysanthemum, 200g privet fruit, 220g turnip, 60g aloe vera, 80g cork bark, 60g toosendan, 60g gardenia, 70g safflower, 200g white chrysanthemum, 130g licorice, wolfberry 160g, 150g yam and 220g ginger.

[0068] Its preparation method comprises the following steps:

[0069] Step 1: Mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 75% that is 6 times the mass of the mixture, heat and reflux for 90 minutes, extract, filter to obtain the first extract, and filter the obtained dregs Then add ethanol with an alcohol concentration of 75% relative to the quality of the dregs, heat and reflux for 60 minutes, extract, filter to obtain the second extract, combine the first extract and the second extract, and concentrate under reduced pressure to remove the ethanol solvent , dry to obtain a dry p...

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Abstract

The invention discloses a traditional Chinese medicinal preparation for treating glaucoma and a preparation method thereof. The traditional Chinese medicinal preparation comprises the following active pharmaceutical ingredients in parts by weight: 3-8 parts of xanthium strumarium, 10-15 parts of herbof indian pentanema, 10-15 parts of corispermum hyssopifolium, 15-25 parts of glossy privet fruit, 15-25 parts of turnip, 3-8 parts of asparagus, 5-10 parts of cortex phellodendri, 3-8 parts of zechwan chinaberry fruit, 5-10 parts of cape jasmine, 5-10 parts of safflower, 15-25 parts of white chrysanthemum, 10-15 parts of liquorice, 15-25 of lyceum barbarum, 10-15 parts of yam and 15-25 of ginger. The traditional Chinese medicinal preparation provided by the invention is prepared by utilizing traditional Chinese medicine theory, is equally important in treatment and benefiting and has the advantages of small side effect, good curative effect, low cost, high cure rate, no drug resistance and convenience in taking; the traditional Chinese medicinal preparation can well control postoperative intraocular pressure on the basis of operative treatment, prevents glaucomatous optic neuropathy and better treats glaucoma.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine preparation for treating glaucoma and a preparation method thereof. Background technique [0002] Glaucoma is an eye disease in which the intraocular pressure is intermittently or continuously elevated. Sustained high intraocular pressure can cause damage to various parts of the eyeball and visual function. If it is not treated in time, the visual field may be completely lost and blindness may result. Glaucoma is one of the three major blindness diseases that cause blindness in humans, with an incidence rate of 1% in the general population and 2% after the age of 45. [0003] At present, Western medicine mainly adopts the method of surgical treatment, but surgical treatment has its adaptability and limitations. In addition to the high cost, there are high requirements for the conditions of the operation, especially the technical level of the docto...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61P27/06
Inventor 刘召英孟宪明
Owner 刘召英
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