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Sea cucumber seminal vesicle extract for treating partial androgen deficiency of aging males (PADAM)

An extract and androgen technology, applied in the field of health medicine and food, can solve the problems of unutilized nutritional components and active factors, unclear components and biological functions, and discarding, etc. Effect

Inactive Publication Date: 2013-09-25
QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Sea cucumber seminal vesicles are the reproductive organs of sea cucumbers, which have excellent nutritional value, but they are mostly discarded as waste during the processing of sea cucumbers, resulting in the unused nutrients and active factors, resulting in a lot of waste
At present, there are few reports on the research on sea cucumber seminal vesicles at home and abroad. The components and biological functions of sea cucumber seminal vesicles are still unclear. Therefore, it is of great practical significance to separate and extract the active ingredients in sea cucumber seminal vesicles and apply them to the treatment of PADAM.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0020] 1. Preparation of PADAM extract from sea cucumber seminal vesicles:

[0021] Sea cucumber seminal vesicles were provided by Dalian Bangchuidao Seafood Co., Ltd.

[0022] (1) The pre-frozen sea cucumber seminal vesicles were freeze-dried and crushed;

[0023] (2) Add absolute ethanol at a mass ratio of 1:10, stir and extract at 30°C for 3 h; take the filtrate after filtration, repeat the above operation for the residue, and combine the filtrates;

[0024] (3) Ethanol was recovered by a rotary evaporator, and the concentrated solution was vacuum-dried to obtain sea cucumber seminal vesicle extract.

[0025] 2. Preparation of tablets and capsules:

[0026] (1) Preparation of sea cucumber seminal vesicle extract capsule preparation of the present invention

[0027] Weigh 200 mg of the sea cucumber seminal vesicle extract prepared in the above steps, simultaneously weigh 295 mg of starch and 5 mg of magnesium stearate, mix them uniformly, and fill them into capsules.

[...

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PUM

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Abstract

The invention discloses a sea cucumber seminal vesicle extract for treating partial androgen deficiency of aging males (PADAM) and a preparation method thereof and relates to the technical field of processes for extracting active substances from sea cucumber seminal vesicles. The preparation method of the sea cucumber seminal vesicle extract comprises the steps of carrying out freeze drying on right amount of the pre-frozen sea cucumber seminal vesicle, smashing, adding absolute ethyl alcohol in the mass ratio of 1:10, carrying out stirring extraction at 30 DEG C for 3 hours, taking out the filtrate after filtering, repeatedly carrying out the operations on the residue, mixing the filtrates, recovering the ethyl alcohol by using a rotary evaporator, and carrying out vacuum drying on the concentrated solution to obtain the sea cucumber seminal vesicle extract. The sea cucumber seminal vesicle extract can be prepared into tablets and capsules and is used for treating the PADAM.

Description

technical field [0001] The invention relates to the technical field of health-care medicine and food, in particular to the application of sea cucumber seminal vesicle extract in treating partial androgen deficiency syndrome in middle-aged and elderly men. Background technique [0002] Partial androgen deficiency syndrome in middle-aged and elderly males (PADAM) is a group of clinical syndromes caused by the gradual aging mechanism, endocrine function, especially hypogonadism, and male hormone regulation disorder when men transition from middle-aged to old age; It is called andropause syndrome, menopausal depression, and male senility. [0003] At present, the international community advocates testosterone supplementation therapy for PADAM patients, such as testosterone fatty acid ester (Andrell), methyltestosterone, testosterone propionate, etc., and testosterone supplementation therapy can only relieve part of the symptoms, and the resulting safety Sexual problems have gra...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/56A61P15/12A61P15/00A61K35/616
Inventor 高华刘坤石振艳刘占涛郭锡春张婕
Owner QINGDAO UNIV
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