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A kind of pharmaceutical composition for treating affective mental disorders

A technology for mental disorders and compositions, applied in the directions of drug combinations, nervous system diseases, pharmaceutical formulations, etc., to achieve the effects of reducing dosage, enhancing curative effect, and reducing toxic and side effects

Active Publication Date: 2015-12-30
SICHUAN CREDIT PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] There is currently no highly selective 5-HT 1A Compatibility of receptor agonists and mood stabilizers for the treatment of anxiety, depression, bisexual disorder and their comorbidities

Method used

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  • A kind of pharmaceutical composition for treating affective mental disorders
  • A kind of pharmaceutical composition for treating affective mental disorders
  • A kind of pharmaceutical composition for treating affective mental disorders

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] prescription:

[0038]

[0039] Preparation:

[0040] Mix tandospirone citrate and sodium valproate with auxiliary materials uniformly under the environmental conditions of certain temperature and humidity, and then granulate, compress or directly compress tablets to obtain tablets; or The prepared granules are filled into capsules to obtain capsules.

Embodiment 2

[0042] prescription:

[0043]

[0044] Preparation:

[0045] Mix tandospirone citrate and sodium valproate with auxiliary materials uniformly under the environmental conditions of certain temperature and humidity, and then granulate, compress or directly compress tablets to obtain tablets; or The prepared granules are filled into capsules to obtain capsules.

Embodiment 3

[0047] prescription:

[0048]

[0049]

[0050] Preparation:

[0051] Mix buspirone and sodium valproate with auxiliary materials uniformly under certain temperature and humidity conditions, and then granulate, compress or directly compress tablets to obtain tablets; or prepare the prepared Fill capsules with granules to obtain capsules.

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PUM

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Abstract

The invention provides a pharmaceutical composition comprising a 5-HT1A receptor stimulant and a mood stabilizer. In the pharmaceutical composition, the weight ratio of the 5-HT1A receptor stimulant to the mood stabilizer is (1-40):(50-800). The invention also provides application of the pharmaceutical composition. Through combination of selective 5-HT1A receptor stimulant and the mood stabilizer which have different action mechanisms, the drug can treat anxiety, depression and / or biphasic emotional disorder and the like at the same time; the disease treatment spectrum is wider; furthermore, the curative effect after combination is more significant than that of single medicine, and the toxic and side effects are lower; a novel drug selection is provided to patients who are intolerant to first-line anti-anxiety or anti-depression or drugs.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating emotional disorders. Background technique [0002] Anxiety disorder, also known as anxiety neurosis, is an emotional mental disorder dominated by anxiety, mainly manifested as episodic or persistent anxiety, tension, panic and restlessness, accompanied by autonomic disturbance Symptoms such as muscle tension and restlessness in movement. Among them, social and psychological factors play a vital role in the onset of anxiety disorders. With the rapid development of modern society and economy, the pace of life is accelerating, social competition is becoming more intense, and social pressure is increasing. Crowded living space, noise, environmental pollution and other comprehensive factors have led to a rapid increase in the incidence of anxiety disorders. [0003] Depression is also a kind of affective mental disorder, which is mainly manifested as obvious and persistent low mood, accomp...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K45/06A61K31/506A61P25/24A61P25/22A61P25/18A61K31/19
Inventor 傅霖林科名陈刚
Owner SICHUAN CREDIT PHARMA
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